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Fluorescence imaging is indispensable to biology and neuroscience. The need for large-scale imaging in freely behaving animals has further driven the development in miniaturized microscopes (miniscopes). However, conventional microscopes /…

Optics · Physics 2020-10-29 Yujia Xue , Ian G. Davison , David A. Boas , Lei Tian

Estimating properties of star clusters from unresolved broadband photometry is a challenging problem that is classically tackled by spectral energy distribution (SED) fitting methods that are based on simple stellar population models.…

Machine learning techniques can reveal hidden structure in large data amounts and can potentially extent or even replace analytical scientific methods. In nanophotonics, modes can increase the light yield from emitters located inside the…

Optics · Physics 2018-10-02 Carlo Barth , Christiane Becker

Structured illumination in Single Molecule Localization Microscopy provides new information on the position of molecules and thus improves the localization precision compared to standard localization methods. Here, we used a time-shifted…

Dataset distillation reduces the storage and computational consumption of training a network by generating a small surrogate dataset that encapsulates rich information of the original large-scale one. However, previous distillation methods…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Jianyang Gu , Saeed Vahidian , Vyacheslav Kungurtsev , Haonan Wang , Wei Jiang , Yang You , Yiran Chen

Far-field characterization of small objects is severely constrained by the diffraction limit. Existing tools achieving sub-diffraction resolution often utilize point-by-point image reconstruction via scanning or labelling. Here, we present…

Real-time feedback-driven single-particle tracking is a technique that uses feedback control to enable single-molecule spectroscopy of freely diffusing particles in native or near-native environments. A number of different RT-FD-SPT…

Instrumentation and Detectors · Physics 2022-09-28 Bertus van Heerden , Tjaart P. J. Krüger

Hyperspectral unmixing (HU) is a crucial signal processing procedure to identify the underlying materials (or endmembers) and their corresponding proportions (or abundances) from an observed hyperspectral scene. A well-known blind HU…

Computational Geometry · Computer Science 2016-04-20 Chia-Hsiang Lin , Chong-Yung Chi , Yu-Hsiang Wang , Tsung-Han Chan

Many low-dose CT imaging methods rely on supervised learning, which requires a large number of paired noisy and clean images. However, obtaining paired images in clinical practice is challenging. To address this issue, zero-shot…

Image and Video Processing · Electrical Eng. & Systems 2025-04-11 Yongyi Shi , Ge Wang

Fluorescence imaging is an essential diagnostic tool in many fields, but diffraction-limited optical imaging at depth is limited by scattering. Here, we present a method based on multiple random illuminations, combined with a computational…

Optics · Physics 2026-03-30 Lei Zhu , Tengfei Wu , Bernhard Rauer , Hilton B. de Aguiar , Sylvain Gigan

In hematology, computational models offer significant potential to improve diagnostic accuracy, streamline workflows, and reduce the tedious work of analyzing single cells in peripheral blood or bone marrow smears. However, clinical…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Valentin Koch , Sophia J. Wagner , Salome Kazeminia , Ece Sancar , Matthias Hehr , Julia Schnabel , Tingying Peng , Carsten Marr

Segmenting thin structures like infrastructure cracks and anatomical vessels is a task hampered by topology-sensitive geometry, high annotation costs, and poor generalization across domains. Existing methods address these challenges in…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Babak Asadi , Peiyang Wu , Mani Golparvar-Fard , Viraj Shah , Ramez Hajj

Old photos preserve invaluable historical memories, making their restoration and colorization highly desirable. While existing restoration models can address some degradation issues like denoising and scratch removal, they often struggle…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Bingchen Li , Zhixin Wang , Fan Li , Jiaqi Xu , Jiaming Guo , Renjing Pei , Xin Li , Zhibo Chen

Single Molecule Localization Microscopy (SMLM) enables the acquisition of high-resolution images by alternating between activation of a sparse subset of fluorescent molecules present in a sample and localization. In this work, the…

Image and Video Processing · Electrical Eng. & Systems 2018-12-17 Arne Bechensteen , Laure Blanc-Féraud , Gilles Aubert

A new method for solving small X-ray structures with up to couple of hundreds of atoms in the unit cell has been developed. The method works by locating atoms one-by-one via global minimization of a newly defined single-atom R1 factor in…

Data Analysis, Statistics and Probability · Physics 2024-03-21 Xiaodong Zhang

Although cross-domain few-shot learning (CDFSL) for hyper-spectral image (HSI) classification has attracted significant research interest, existing works often rely on an unrealistic data augmentation procedure in the form of external noise…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Naeem Paeedeh , Mahardhika Pratama , Ary Shiddiqi , Zehong Cao , Mukesh Prasad , Wisnu Jatmiko

Serial crystallography experiments routinely produce thousands of diffraction patterns from crystals in random orientations. To turn this stream of images into a usable dataset, each pattern must be indexed before integration and merging…

Computational Physics · Physics 2025-12-01 Marc M Nasser , Frédéric Poitevin , Kevin M Dalton

Fine-grained clustering is a practical yet challenging task, whose essence lies in capturing the subtle differences between instances of different classes. Such subtle differences can be easily disrupted by data augmentation or be…

Computer Vision and Pattern Recognition · Computer Science 2024-12-30 Ruohong Yang , Peng Hu , Xi Peng , Xiting Liu , Yunfan Li

Infrared imagery enables temperature-based scene understanding using passive sensors, particularly under conditions of low visibility where traditional RGB imaging fails. Yet, developing downstream vision models for infrared applications is…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Kai A. Horstmann , Maxim Clouser , Kia Khezeli

While super-resolution (SR) methods based on diffusion models exhibit promising results, their practical application is hindered by the substantial number of required inference steps. Recent methods utilize degraded images in the initial…

Computer Vision and Pattern Recognition · Computer Science 2023-11-28 Yufei Wang , Wenhan Yang , Xinyuan Chen , Yaohui Wang , Lanqing Guo , Lap-Pui Chau , Ziwei Liu , Yu Qiao , Alex C. Kot , Bihan Wen