English
Related papers

Related papers: Statistical methods for reference-free single-mole…

200 papers

Event-based image sensors provide microsecond temporal resolution but lack spectral discrimination, whereas diffractive spectral imagers encode wavelength information at conventional frame rates. We introduce a fluorescence microscopy…

Optics · Physics 2026-03-20 Richard G. Baird , Boyden Myers , Erik M. Jorgensen , Rajesh Menon

Matched filters (MFs) are elegant and widely used tools to detect and measure signals that resemble a known template in noisy data. However, they can perform poorly in the presence of contaminating sources of similar or smaller spatial…

Instrumentation and Methods for Astrophysics · Physics 2019-02-01 Jens Erler , Miriam E. Ramos-Ceja , Kaustuv Basu , Frank Bertoldi

We present a new methodology for the estimation of stellar atmospheric parameters from narrow- and intermediate-band photometry of the Javalambre Photometric Local Universe Survey (J-PLUS), and propose a method for target pre-selection of…

Learning to recognize novel visual categories from a few examples is a challenging task for machines in real-world industrial applications. In contrast, humans have the ability to discriminate even similar objects with little supervision.…

Computer Vision and Pattern Recognition · Computer Science 2020-06-02 Xin Sun , Hongwei Xv , Junyu Dong , Qiong Li , Changrui Chen

While the near-infrared wavelength regime is becoming more and more important for astrophysics there is a marked lack of spectrophotometric standard star data that would allow the flux calibration of such data. Furthermore, flux calibrating…

Instrumentation and Methods for Astrophysics · Physics 2014-08-11 S. Moehler , A. Modigliani , W. Freudling , N. Giammichele , A. Gianninas , A. Gonneau , W. Kausch , A. Lancon , S. Noll , T. Rauch , J. Vinther

X-ray Free Electron Lasers (XFEL) are revolutionary photons sources, whose ultrashort, brilliant pulses are expected to allow single molecule diffraction experiments providing structural information on the atomic length scale. This ultimate…

Optics · Physics 2015-05-20 Andrea Fratalocchi , Giancarlo Ruocco

A simple method was developed to observe the interference patterns of the light reflected by the interfaces of thin liquid films. Employing a fluorescent microscope with epi-illumination, we collected the 2D patterns of interference fringes…

Optics · Physics 2010-06-14 V. Berejnov , D. Li

In order to discern aggregation in solutions, we present a quantum mechanical analog of the photon statistics from fluorescent molecules diffusing through a focused beam. A generating functional is developed to fully describe the…

Biological Physics · Physics 2009-11-10 Hai-cang Ren , Noel L. Goddard , Gregoire Altan-Bonnet , Albert Libchaber

Multi-view data clustering refers to categorizing a data set by making good use of related information from multiple representations of the data. It becomes important nowadays because more and more data can be collected in a variety of…

Artificial Intelligence · Computer Science 2016-09-16 Yangtao Wang , Lihui Chen

Tapered optical fibers (TFs), with diameters gradually reduced from hundreds of microns to the micron scale, offer key advantages over conventional flat optical fibers (FFs), including uniform illumination, efficient long-range signal…

Optics · Physics 2026-02-03 Mingliang Xu , Fangyuan Li , Yuxin Leng , Ruxin Li , Fei He

Super-resolution microscopy has revolutionized optical fluorescence imaging by improving 3D resolution by 1-2 orders of magnitude. While different methods can successfully increase the resolution, all methods share significant differences…

Biological Physics · Physics 2015-01-26 Thomas Pengo , Nicolas Olivier , Suliana Manley

Single-molecule detection enables direct observation of individual biomolecular events, providing mechanistic insights into biological processes and offering a powerful tool for disease diagnostics. However, the fundamental scale mismatch…

Optics · Physics 2025-10-14 Guifeng Li , Chaoyang Gong

We present an ultra-efficient post-training method for shortcutting large-scale pre-trained flow matching diffusion models into efficient few-step samplers, enabled by novel velocity field self-distillation. While shortcutting in flow…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Xu Cai , Yang Wu , Qianli Chen , Haoran Wu , Lichuan Xiang , Hongkai Wen

We suggest an approach to microrheology based on optical traps in order to measure fluid fluxes around singular points of fluid flows. We experimentally demonstrate this technique, applying it to the characterization of controlled flows…

Optics · Physics 2008-04-11 Giorgio Volpe , Giovanni Volpe , Dmitri Petrov

An outstanding question in X-ray single particle imaging experiments has been the feasibility of imaging sub 10-nm-sized biomolecules under realistic experimental conditions where very few photons are expected to be measured in a single…

We establish a method, called pbFFS for photobleaching Fluctuation Fluorescence Spectroscopy, which aims at characterizing molecules or particles labelled with a unknown distribution or fluorophores. Using photobleaching as a control…

Lensless illumination single-pixel imaging with a multicore fiber (MCF) is a computational imaging technique that enables potential endoscopic observations of biological samples at cellular scale. In this work, we show that this technique…

Signal Processing · Electrical Eng. & Systems 2023-07-18 Olivier Leblanc , Matthias Hofer , Siddharth Sivankutty , Hervé Rigneault , Laurent Jacques

We introduce HAMscope, a compact, snapshot hyperspectral autofluorescence miniscope that enables real-time, label-free molecular imaging in a wide range of biological systems. By integrating a thin polymer diffuser into a widefield…

We propose Manifold Free-Form Flows (M-FFF), a simple new generative model for data on manifolds. The existing approaches to learning a distribution on arbitrary manifolds are expensive at inference time, since sampling requires solving a…

Machine Learning · Computer Science 2024-11-26 Peter Sorrenson , Felix Draxler , Armand Rousselot , Sander Hummerich , Ullrich Köthe

Fast 3D super-resolution imaging is essential for decoding rapidly occurring biological processes. Encoding single molecules to their respective planes enable simultaneous multi-plane super-resolution volume imaging. This saves the…

Biological Physics · Physics 2016-08-04 Partha Pratim Mondal
‹ Prev 1 4 5 6 7 8 10 Next ›