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Multi-modal magnetic resonance imaging (MRI) is essential for providing complementary information about brain anatomy and pathology, leading to more accurate diagnoses. However, obtaining high-quality multi-modal MRI in a clinical setting…

Image and Video Processing · Electrical Eng. & Systems 2025-04-15 Minjoo Lim , Bogyeong Kang , Tae-Eui Kam

Unsupervised learning can leverage large-scale data sources without the need for annotations. In this context, deep learning-based auto encoders have shown great potential in detecting anomalies in medical images. However, state-of-the-art…

Machine Learning · Computer Science 2018-12-17 David Zimmerer , Simon A. A. Kohl , Jens Petersen , Fabian Isensee , Klaus H. Maier-Hein

Accurate prediction of cardiovascular diseases remains imperative for early diagnosis and intervention, necessitating robust and precise predictive models. Recently, there has been a growing interest in multi-modal learning for uncovering…

Computer Vision and Pattern Recognition · Computer Science 2024-11-12 Francesco Girlanda , Olga Demler , Bjoern Menze , Neda Davoudi

Variational autoencoders are powerful algorithms for identifying dominant latent structure in a single dataset. In many applications, however, we are interested in modeling latent structure and variation that are enriched in a target…

Machine Learning · Computer Science 2019-02-14 Abubakar Abid , James Zou

The integration of medical images with clinical context is essential for generating accurate and clinically interpretable radiology reports. However, current automated methods often rely on resource-heavy Large Language Models (LLMs) or…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Nagur Shareef Shaik , Teja Krishna Cherukuri , Adnan Masood , Dong Hye Ye

Learning a robust Variational Autoencoder (VAE) is a fundamental step for many deep learning applications in medical image analysis, such as MRI synthesizes. Existing brain VAEs predominantly focus on single-modality data (i.e., T1-weighted…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Mingjie Li , Edward Kim , Yue Zhao , Ehsan Adeli , Kilian M. Pohl

Learning generative models that span multiple data modalities, such as vision and language, is often motivated by the desire to learn more useful, generalisable representations that faithfully capture common underlying factors between the…

Machine Learning · Statistics 2019-11-11 Yuge Shi , N. Siddharth , Brooks Paige , Philip H. S. Torr

Unsupervised learning of disease subtypes from multi-omics data presents a significant opportunity for advancing personalized medicine. We introduce OmicsCL, a modular contrastive learning framework that jointly embeds heterogeneous omics…

Machine Learning · Computer Science 2025-05-02 Atahan Karagoz

Variational autoencoders (VAEs) are latent variable models that can generate complex objects and provide meaningful latent representations. Moreover, they could be further used in downstream tasks such as classification. As previous work…

Machine Learning · Computer Science 2022-10-13 Anna Kuzina , Max Welling , Jakub M. Tomczak

A number of variational autoencoders (VAEs) have recently emerged with the aim of modeling multimodal data, e.g., to jointly model images and their corresponding captions. Still, multimodal VAEs tend to focus solely on a subset of the…

Machine Learning · Computer Science 2022-06-10 Adrián Javaloy , Maryam Meghdadi , Isabel Valera

In this paper, we first extend the recent Masked Auto-Encoder (MAE) model from a single modality to audio-visual multi-modalities. Subsequently, we propose the Contrastive Audio-Visual Masked Auto-Encoder (CAV-MAE) by combining contrastive…

We propose a new deep learning method for tumour segmentation when dealing with missing imaging modalities. Instead of producing one network for each possible subset of observed modalities or using arithmetic operations to combine feature…

Image and Video Processing · Electrical Eng. & Systems 2019-10-22 Reuben Dorent , Samuel Joutard , Marc Modat , Sébastien Ourselin , Tom Vercauteren

Current deep learning-based manifold learning algorithms such as the variational autoencoder (VAE) require fully sampled data to learn the probability density of real-world datasets. Once learned, the density can be used for a variety of…

Image and Video Processing · Electrical Eng. & Systems 2021-12-13 Qing Zou , Abdul Haseeb Ahmed , Prashant Nagpal , Sarv Priya , Rolf Schulte , Mathews Jacob

We propose the Motion Capsule Autoencoder (MCAE), which addresses a key challenge in the unsupervised learning of motion representations: transformation invariance. MCAE models motion in a two-level hierarchy. In the lower level, a…

Computer Vision and Pattern Recognition · Computer Science 2021-10-04 Ziwei Xu , Xudong Shen , Yongkang Wong , Mohan S Kankanhalli

Lung cancer is the leading cause of cancer death worldwide. The critical reason for the deaths is delayed diagnosis and poor prognosis. With the accelerated development of deep learning techniques, it has been successfully applied…

Image and Video Processing · Electrical Eng. & Systems 2021-06-15 Yujiao Wu , Jie Ma , Xiaoshui Huang , Sai Ho Ling , Steven Weidong Su

Data augmentation is a powerful technique for improving the performance of the few-shot classification task. It generates more samples as supplements, and then this task can be transformed into a common supervised learning issue for…

Computer Vision and Pattern Recognition · Computer Science 2021-06-29 Yi Zhang , Sheng Huang , Xi Peng , Dan Yang

Cancer is a primary cause of human death, but discovering drugs and tailoring cancer therapies are expensive and time-consuming. We seek to facilitate the discovery of new drugs and treatment strategies for cancer using variational…

Machine Learning · Computer Science 2021-04-16 Hongyuan Dong , Jiaqing Xie , Zhi Jing , Dexin Ren

Cancer is a complex disease with significant social and economic impact. Advancements in high-throughput molecular assays and the reduced cost for performing high-quality multi-omics measurements have fuelled insights through machine…

Machine Learning · Computer Science 2022-06-28 Pedro Henrique da Costa Avelar , Roman Laddach , Sophia Karagiannis , Min Wu , Sophia Tsoka

Multimodal retrieval, which seeks to retrieve relevant content across modalities such as text or image, supports applications from AI search to contents production. Despite the success of separate-encoder approaches like CLIP align…

Computation and Language · Computer Science 2025-10-20 Qiyu Wu , Shuyang Cui , Satoshi Hayakawa , Wei-Yao Wang , Hiromi Wakaki , Yuki Mitsufuji

Making sense of multiple modalities can yield a more comprehensive description of real-world phenomena. However, learning the co-representation of diverse modalities is still a long-standing endeavor in emerging machine learning…

Artificial Intelligence · Computer Science 2022-12-21 Jinzhao Zhou , Yiqun Duan , Zhihong Chen , Yu-Cheng Chang , Chin-Teng Lin