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Extracorporeal membrane oxygenation (ECMO) is an essential life-supporting modality for COVID-19 patients who are refractory to conventional therapies. However, the proper treatment decision has been the subject of significant debate and it…

Machine Learning · Computer Science 2023-07-10 Bing Xue , Ahmed Sameh Said , Ziqi Xu , Hanyang Liu , Neel Shah , Hanqing Yang , Philip Payne , Chenyang Lu

In the following short article we adapt a new and popular machine learning model for inference on medical data sets. Our method is based on the Variational AutoEncoder (VAE) framework that we adapt to survival analysis on small data sets…

Machine Learning · Statistics 2018-12-06 Cédric Beaulac , Jeffrey S. Rosenthal , David Hodgson

Wearable devices enable continuous multi-modal physiological and behavioral monitoring, yet analysis of these data streams faces fundamental challenges including the lack of gold-standard labels and incomplete sensor data. While…

Machine Learning · Statistics 2025-09-22 Howon Ryu , Yuliang Chen , Yacun Wang , Andrea Z. LaCroix , Chongzhi Di , Loki Natarajan , Yu Wang , Jingjing Zou

Most multi-view clustering methods are limited by shallow models without sound nonlinear information perception capability, or fail to effectively exploit complementary information hidden in different views. To tackle these issues, we…

Machine Learning · Computer Science 2022-10-14 Fu Lele , Zhang Lei , Yang Jinghua , Chen Chuan , Zhang Chuanfu , Zheng Zibin

Medical image segmentation is a fundamental yet challenging task due to the arduous process of acquiring large volumes of high-quality labeled data from experts. Contrastive learning offers a promising but still problematic solution to this…

Computer Vision and Pattern Recognition · Computer Science 2025-02-14 Shuang Zeng , Lei Zhu , Xinliang Zhang , Micky C Nnamdi , Wenqi Shi , J Ben Tamo , Qian Chen , Hangzhou He , Lujia Jin , Zifeng Tian , Qiushi Ren , Zhaoheng Xie , Yanye Lu

Devising deep latent variable models for multi-modal data has been a long-standing theme in machine learning research. Multi-modal Variational Autoencoders (VAEs) have been a popular generative model class that learns latent representations…

Machine Learning · Statistics 2024-09-25 Marcel Hirt , Domenico Campolo , Victoria Leong , Juan-Pablo Ortega

Human perception is inherently multimodal. We integrate, for instance, visual, proprioceptive and tactile information into one experience. Hence, multimodal learning is of importance for building robotic systems that aim at robustly…

Machine Learning · Computer Science 2024-11-04 Carlotta Langer , Yasmin Kim Georgie , Ilja Porohovoj , Verena Vanessa Hafner , Nihat Ay

Depression poses serious public health risks, including suicide, underscoring the urgency of timely and scalable screening. Multimodal automatic depression detection (ADD) offers a promising solution; however, widely studied audio- and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Jiuyi Chen , Mingkui Tan , Haifeng Lu , Qiuna Xu , Zhihua Wang , Runhao Zeng , Xiping Hu

Medical visual question answering (VQA) is a challenging task that requires answering clinical questions of a given medical image, by taking consider of both visual and language information. However, due to the small scale of training data…

Computer Vision and Pattern Recognition · Computer Science 2023-07-12 Pengfei Li , Gang Liu , Jinlong He , Zixu Zhao , Shenjun Zhong

Multimodal evidence is critical in computational pathology: gigapixel whole slide images capture tumor morphology, while patient-level clinical descriptors preserve complementary context for prognosis. Integrating such heterogeneous signals…

Computer Vision and Pattern Recognition · Computer Science 2026-02-05 Chengying She , Chengwei Chen , Xinran Zhang , Ben Wang , Lizhuang Liu , Chengwei Shao , Yun Bian

Non-invasive inference of molecular tumor characteristics from medical imaging is a central goal of radiogenomics, particularly in glioblastoma (GBM), where O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation carries…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Mariya Miteva , Maria Nisheva-Pavlova

While disentangled representations have shown promise in generative modeling and representation learning, their downstream usefulness remains debated. Recent studies re-defined disentanglement through a formal connection to symmetries,…

Machine Learning · Computer Science 2024-11-04 Cristian Meo , Louis Mahon , Anirudh Goyal , Justin Dauwels

Multi-modal semantic understanding requires integrating information from different modalities to extract users' real intention behind words. Most previous work applies a dual-encoder structure to separately encode image and text, but fails…

Computation and Language · Computer Science 2024-03-12 Ming Zhang , Ke Chang , Yunfang Wu

We present a coupled Variational Auto-Encoder (VAE) method that improves the accuracy and robustness of the probabilistic inferences on represented data. The new method models the dependency between input feature vectors (images) and weighs…

Machine Learning · Computer Science 2025-11-25 Shichen Cao , Jingjing Li , Kenric P. Nelson , Mark A. Kon

Learning representations of multimodal data that are both informative and robust to missing modalities at test time remains a challenging problem due to the inherent heterogeneity of data obtained from different channels. To address it, we…

Machine Learning · Computer Science 2022-11-21 Petra Poklukar , Miguel Vasco , Hang Yin , Francisco S. Melo , Ana Paiva , Danica Kragic

Multimodal survival prediction, a crucial yet challenging task, demands the integration of multimodal medical data (\eg Whole Slide Images (WSIs) and Genomic Profiles) to achieve accurate prognostic modeling. Given the inherent…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Huayi Wang , Haochao Ying , Yuyang Xu , Qiyao Zheng , jun wang , Cheng Zhang , Ying Sun , Jian Wu

Multimodal magnetic resonance imaging (MRI) provides complementary information for sub-region analysis of brain tumors. Plenty of methods have been proposed for automatic brain tumor segmentation using four common MRI modalities and…

Image and Video Processing · Electrical Eng. & Systems 2023-03-10 Hong Liu , Dong Wei , Donghuan Lu , Jinghan Sun , Liansheng Wang , Yefeng Zheng

Accurate segmentation of brain images typically requires the integration of complementary information from multiple image modalities. However, clinical data for all modalities may not be available for every patient, creating a significant…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Haitao Li , Ziyu Li , Yiheng Mao , Zhengyao Ding , Zhengxing Huang

Elucidating the functional mechanisms of the primary visual cortex (V1) remains a fundamental challenge in systems neuroscience. Current computational models face two critical limitations, namely the challenge of cross-modal integration…

Neurons and Cognition · Quantitative Biology 2024-12-20 Yu Zhu , Bo Lei , Chunfeng Song , Wanli Ouyang , Shan Yu , Tiejun Huang

Survival outcome assessment is challenging and inherently associated with multiple clinical factors (e.g., imaging and genomics biomarkers) in cancer. Enabling multimodal analytics promises to reveal novel predictive patterns of patient…

Computer Vision and Pattern Recognition · Computer Science 2023-07-25 Kexin Ding , Mu Zhou , Dimitris N. Metaxas , Shaoting Zhang