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Mueller polarimetry is a powerful technique with broad applications in astronomy, remote sensing, advanced material analysis, and biomedical imaging. However, instrumental constraints frequently restrict the measurement to an incomplete…

The structure of grey matter has long been a key focus in neuroscience, as cell morphology varies by type and can be affected by neurological conditions. Understanding these variations is essential for studying brain function and disease.…

Biological Physics · Physics 2025-08-27 Charlie Aird-Rossiter , Hui Zhang , Daniel C. Alexander , Derek K. Jones , Marco Palombo

The elasticity of soft tissues has been widely considered as a characteristic property to differentiate between healthy and vicious tissues and, therefore, motivated several elasticity imaging modalities, such as Ultrasound Elastography,…

Image and Video Processing · Electrical Eng. & Systems 2022-05-30 Weiguo Cao , Marc J. Pomeroy , Zhengrong Liang , Yongfeng Gao , Yongyi Shi , Jiaxing Tan , Fangfang Han , Jing Wang , Jianhua Ma , Hongbin Lu , Almas F. Abbasi , Perry J. Pickhardt

This article presents MuMFiM, an open source application for multiscale modeling of fibrous materials on massively parallel computers. MuMFiM uses two scales to represent fibrous materials such as biological network materials (extracellular…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-05-04 Jacob Merson , Catalin Picu , Mark S. Shephard

Thyroid cancer is the most common endocrine malignancy, and accurately distinguishing between benign and malignant thyroid tumors is crucial for developing effective treatment plans in clinical practice. Pathologically, thyroid tumors pose…

Image and Video Processing · Electrical Eng. & Systems 2024-01-04 Jia Dong , Yao Yao , Yang Dong , Hui Ma

Due to the lack of efficient mpox diagnostic technology, mpox cases continue to increase. Recently, the great potential of deep learning models in detecting mpox and non-mpox has been proven. However, existing models learn image…

Image and Video Processing · Electrical Eng. & Systems 2023-10-11 Yubiao Yue , Zhenzhang Li

Cellular electron cryo-tomography enables the 3D visualization of cellular organization in the near-native state and at submolecular resolution. However, the contents of cellular tomograms are often complex, making it difficult to…

Quantitative Methods · Quantitative Biology 2017-12-29 Xiangrui Zeng , Miguel Ricardo Leung , Tzviya Zeev-Ben-Mordehai , Min Xu

Collective cell migration in 3D extracellular matrix (ECM) is crucial to many physiological and pathological processes. Migrating cells can generate active pulling forces via actin filament contraction, which are transmitted to the ECM…

Biological Physics · Physics 2019-05-01 Hanqing Nan , Yu Zheng , Shaohua Chen , Christopher Eddy , Jianxiang Tian , Wenxiang Xu , Bo Sun , Yang Jiao

While any two-dimensional mixed state of polarization of light can be represented by a combination of a pure state and a fully random state, any Mueller matrix can be represented by a convex combination of a pure component and three…

Optics · Physics 2017-04-05 Jose J. Gil

Extreme learning machine (ELM) is a methodology for solving partial differential equations (PDEs) using a single hidden layer feed-forward neural network. It presets the weight/bias coefficients in the hidden layer with random values, which…

Numerical Analysis · Mathematics 2025-04-30 Chang-Ock Lee , Youngkyu Lee , Byungeun Ryoo

Cellular bioelectricity describes the biological phenomenon in which cells in living tissue generate and maintain patterns of voltage gradients induced by differing concentrations of charged ions. A growing body of research suggests that…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-09-27 Seth Gilbert , James Maguire , Calvin Newport

More children and adults under the age of 40 die of brain tumor than from any other cancer. Brain surgery constitutes the first and decisive step for the treatment of such tumors. It is extremely crucial to achieve complete tumor resection…

Understanding the causal effects of organ-specific features from medical imaging on clinical outcomes is essential for biomedical research and patient care. We propose a novel Functional Linear Structural Equation Model (FLSEM) to capture…

Methodology · Statistics 2026-01-29 Ting Li , Ethan Fan , Tengfei Li , Hongtu Zhu

Local cancer cell invasion is a complex process involving many cellular and tissue interactions and is an important prerequisite for metastatic spread, the main cause of cancer related deaths. Occurring over many different temporal and…

Tissues and Organs · Quantitative Biology 2019-07-03 Robyn Shuttleworth , Dumitru Trucu

This paper presents a novel Bayesian approach for hyperspectral image unmixing. The observed pixels are modeled by a linear combination of material signatures weighted by their corresponding abundances. A spike-and-slab abundance prior is…

Applications · Statistics 2022-05-04 Zeng Li , Yoann Altmann , Jie Chen , Stephen Mclaughlin , Susanto Rahardja

Matrix factorization methods - including Factor analysis (FA), and Principal Components Analysis (PCA) - are widely used for inferring and summarizing structure in multivariate data. Many matrix factorization methods exist, corresponding to…

Methodology · Statistics 2021-05-04 Wei Wang , Matthew Stephens

Wide-field imaging Mueller polarimetry is a revolutionary, label-free, and non-invasive modality for computer-aided intervention: in neurosurgery it aims to provide visual feedback of white matter fibre bundle orientation from derived…

Refractive index is a fundamental electromagnetic (EM) parameter that can describe photonic continuous media (PCM) traditionally as either transparency or opacity. Recently, topological theory offers a new set of phases to characterize PCM…

Optics · Physics 2025-10-28 Xin-Tao He , Shuo-Shi Zhang , Xiao-Dong Chen , Jian-Wen Dong

Transmission matrix measurements of multimode fibers are now routinely performed in numerous labs, enabling control of the electric field at the distal end of the fiber and paving the way for the potential application to ultrathin medical…

Anatomical mesh segmentation requires models that operate directly on irregular surface geometry while remaining robust to arbitrary patient pose and mesh resolution variation. Existing task-specific mesh and point-cloud methods are not…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Daniel Saragih