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Histopathology, the study and diagnosis of disease through analysis of tissue samples, is an indispensable part of modern medicine. However, the practice is time consuming and labor intensive, compelling efforts to improve the process and…
We propose an imaging method to enhance and reveal structures within samples by using a polarization-based filter. This filter removes the isotropic content while amplifying the anisotropic component of depolarization. Whereas isotropic…
Intravital X-ray microscopy (XRM) in preclinical mouse models is of vital importance for the identification of microscopic structural pathological changes in the bone which are characteristic of osteoporosis. The complexity of this method…
Linear polarimetric transformations of light polarization states by the action of material media are fully characterized by the corresponding Mueller matrices, which contain in an implicit and intricate manner all measurable information on…
For a tailored functionalization of cellulose based papers, the interaction between paper fibers and functional additives have to be understood. Planar cellulose surfaces present a suitable model system for studying the binding of…
White matter fiber clustering (WMFC) enables parcellation of white matter tractography for applications such as disease classification and anatomical tract segmentation. However, the lack of ground truth and the ambiguity of fiber data (the…
When it is polarised, a cell develops an asymmetric distribution of specific molecular markers, cytoskeleton and cell membrane shape. Polarisation can occur spontaneously or be triggered by external signals, like gradients of signalling…
The Transfer Matrix Method (TMM) is a widely used technique for modeling linear propagation of electromagnetic waves through stratified layered media. However, since its extension to inhomogeneous and nonlinear systems is not…
Extracellular matrix (ECM) remodeling is central to a wide variety of healthy and diseased tissue processes. Unfortunately, predicting ECM remodeling under various chemical and mechanical conditions has proven to be excessively challenging,…
The depolarization properties of a medium with associated Mueller matrix M are characterized through two complementary sets of parameters, namely the three indices of polarimetric purity (IPP), which are directly linked to the relative…
Photonic neural networks offer a promising alternative to traditional electronic systems for machine learning accelerators due to their low latency and energy efficiency. However, the challenge of implementing the backpropagation algorithm…
Mueller matrix imaging provides rich, physically meaningful contrast for biomedical tissue analysis, but supervised learning is hindered by scarce dense annotations and strong domain shifts across specimens and acquisition settings. We…
Tumor metastasis, traditionally considered as random spreading of individual cancer cells, has been shown to also involve coordinated collective invasion in the tissue space. Here we demonstrate experimentally and computationally that…
A geometric view of the polarimetric properties of a nondepolarizing medium is presented by means of a pair of vectors in the Poincar\'e sphere. An alternative representation constituted by a set of vectors contained in the equatorial plane…
Quantitative microstructural characterization is fundamental to materials science, where electron micrograph (EM) provides indispensable high-resolution insights. However, progress in deep learning-based EM characterization has been…
Deep learning techniques provide a plausible route towards achieving practical imaging through multimode fibers. The results produced by these methods are often influenced by physical factors like temperature, fiber length, external…
Many polarisation techniques have been harnessed for decades in biological and clinical research, each based upon measurement of the vectorial properties of light or the vectorial transformations imposed on light by objects. Various…
The Mueller Matrix Polar Decomposition method decomposes a Mueller matrix into a diattenuator, a retarder, and a depolarizer. Among these elements, the retarder, which plays a key role in medical and material characterization, is modelled…
Magnetic resonance imaging (MRI) is indispensable for diagnosing and planning treatment in various medical conditions due to its ability to produce multi-series images that reveal different tissue characteristics. However, integrating these…
Cell polarization and directional cell migration can display random, persistent and oscillatory dynamic patterns. However, it is not clear if these polarity patterns can be explained by the same underlying regulatory mechanism. Here, we…