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Noise and artifacts are intrinsic to low dose CT (LDCT) data acquisition, and will significantly affect the imaging performance. Perfect noise removal and image restoration is intractable in the context of LDCT due to the statistical and…

Medical Physics · Physics 2019-07-24 Wenchao Du , Hu Chen , Peixi Liao , Hongyu Yang , Ge Wang , Yi Zhang

Organ segmentation in Positron Emission Tomography (PET) plays a vital role in cancer quantification. Low-dose PET (LDPET) provides a safer alternative by reducing radiation exposure. However, the inherent noise and blurred boundaries make…

Tissues and Organs · Quantitative Biology 2025-06-30 Zanting Ye , Xiaolong Niu , Xu Han , Xuanbin Wu , Wantong Lu , Yijun Lu , Hao Sun , Yanchao Huang , Hubing Wu , Lijun Lu

Low Dose Computed Tomography (LDCT) is clinically desirable due to the reduced radiation to patients. However, the quality of LDCT images is often sub-optimal because of the inevitable strong quantum noise. Inspired by their unprecedent…

Image and Video Processing · Electrical Eng. & Systems 2021-02-02 Ti Bai , Dan Nguyen , Biling Wang , Steve Jiang

Long lasting efforts have been made to reduce radiation dose and thus the potential radiation risk to the patient for computed tomography acquisitions without severe deterioration of image quality. To this end, numerous reconstruction and…

Medical Physics · Physics 2024-10-07 Elias Eulig , Björn Ommer , Marc Kachelrieß

Objective: There exist several X-ray computed tomography (CT) scanning strategies to reduce a radiation dose, such as (1) sparse-view CT, (2) low-dose CT, and (3) region-of-interest (ROI) CT (called interior tomography). To further reduce…

Image and Video Processing · Electrical Eng. & Systems 2025-01-10 Yoseob Han , Dufan Wu , Kyungsang Kim , Quanzheng Li

Perceptual losses have emerged as powerful tools for training networks to enhance Low-Dose Computed Tomography (LDCT) images, offering an alternative to traditional pixel-wise losses such as Mean Squared Error, which often lead to…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Gabriel A. Viana , Luis F. Alves Pereira , Tsang Ing Ren , George D. C. Cavalcanti , Jan Sijbers

Low-dose PET offers a valuable means of minimizing radiation exposure in PET imaging. However, the prevalent practice of employing additional CT scans for generating attenuation maps (u-map) for PET attenuation correction significantly…

Computer Vision and Pattern Recognition · Computer Science 2024-01-26 Bo Zhou , Jun Hou , Tianqi Chen , Yinchi Zhou , Xiongchao Chen , Huidong Xie , Qiong Liu , Xueqi Guo , Yu-Jung Tsai , Vladimir Y. Panin , Takuya Toyonaga , James S. Duncan , Chi Liu

Low-dose computed tomography (CT) images suffer from noise and artifacts due to photon starvation and electronic noise. Recently, some works have attempted to use diffusion models to address the over-smoothness and training instability…

Image and Video Processing · Electrical Eng. & Systems 2024-01-10 Qi Gao , Zilong Li , Junping Zhang , Yi Zhang , Hongming Shan

Ultra sparse-view computed tomography (CT) algorithms can reduce radiation exposure of patients, but those algorithms lack an explicit cycle consistency loss minimization and an explicit log-likelihood maximization in testing. Here, we…

Image and Video Processing · Electrical Eng. & Systems 2021-10-04 Hisaichi Shibata , Shouhei Hanaoka , Yukihiro Nomura , Takahiro Nakao , Tomomi Takenaga , Naoto Hayashi , Osamu Abe

With the development of deep learning, medical image processing has been widely used to assist clinical research. This paper focuses on the denoising problem of low-dose computed tomography using deep learning. Although low-dose computed…

Image and Video Processing · Electrical Eng. & Systems 2026-05-19 Zhilin Guan , Wei Zhang

The unrolling method has been investigated for learning variational models in X-ray computed tomography. However, it has been observed that directly unrolling the regularization model through gradient descent does not produce satisfactory…

Image and Video Processing · Electrical Eng. & Systems 2024-04-19 Yijie Yang , Qifeng Gao , Yuping Duan

Low dose CT is of great interest in these days. Dose reduction raises noise level in projections and decrease image quality in reconstructions. Model based image reconstruction can combine statistical noise model together with prior…

Medical Physics · Physics 2019-10-16 Kaichao Liang , Li Zhang , Yirong Yang , HongKai Yang , Yuxiang Xing

Limited view tomographic reconstruction aims to reconstruct a tomographic image from a limited number of sinogram or projection views arising from sparse view or limited angle acquisitions that reduce radiation dose or shorten scanning…

Image and Video Processing · Electrical Eng. & Systems 2020-09-04 Bo Zhou , S. Kevin Zhou , James S. Duncan , Chi Liu

Deep-learning-based denoising methods have significantly improved Low-Dose CT (LDCT) image quality. However, existing models often over-smooth important anatomical details due to their purely data-driven attention mechanisms. To address…

Image and Video Processing · Electrical Eng. & Systems 2025-04-03 Namhun Kim , UiHyun Cho

As the medical usage of computed tomography (CT) continues to grow, the radiation dose should remain at a low level to reduce the health risks. Therefore, there is an increasing need for algorithms that can reconstruct high-quality images…

Image and Video Processing · Electrical Eng. & Systems 2021-03-10 Davood Karimi , Rabab K. Ward

As a sensitive functional imaging technique, positron emission tomography (PET) plays a critical role in early disease diagnosis. However, obtaining a high-quality PET image requires injecting a sufficient dose (standard dose) of…

Image and Video Processing · Electrical Eng. & Systems 2024-12-06 Caiwen Jiang , Mianxin Liu , Kaicong Sun , Dinggang Shen

Image-generative artificial intelligence (AI) has garnered significant attention in recent years. In particular, the diffusion model, a core component of generative AI, produces high-quality images with rich diversity. In this study, we…

Computer Vision and Pattern Recognition · Computer Science 2024-09-13 Sho Ozaki , Shizuo Kaji , Toshikazu Imae , Kanabu Nawa , Hideomi Yamashita , Keiichi Nakagawa

Low Dose Computed Tomography suffers from a high amount of noise and/or undersampling artefacts in the reconstructed image. In the current article, a Deep Learning technique is exploited as a regularization term for the iterative…

Image and Video Processing · Electrical Eng. & Systems 2019-06-04 Shabab Bazrafkan , Vincent Van Nieuwenhove , Joris Soons , Jan De Beenhouwer , Jan Sijbers

Incomplete-view computed tomography (CT) can shorten the data acquisition time and allow scanning of large objects, including sparse-view and limited-angle scenarios, each with various settings, such as different view numbers or angular…

Image and Video Processing · Electrical Eng. & Systems 2024-03-13 Chenglong Ma , Zilong Li , Junjun He , Junping Zhang , Yi Zhang , Hongming Shan

Low-dose CT has been a key diagnostic imaging modality to reduce the potential risk of radiation overdose to patient health. Despite recent advances, CNN-based approaches typically apply filters in a spatially invariant way and adopt…

Image and Video Processing · Electrical Eng. & Systems 2021-07-27 Lu Xu , Yuwei Zhang , Ying Liu , Daoye Wang , Mu Zhou , Jimmy Ren , Jingwei Wei , Zhaoxiang Ye