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Deep neural networks have a great potential to improve image denoising in low-dose computed tomography (LDCT). Popular ways to increase the network capacity include adding more layers or repeating a modularized clone model in a sequence. In…

Image and Video Processing · Electrical Eng. & Systems 2020-05-15 Siqi Li , Guobao Wang

Despite the indispensable role of X-ray computed tomography (CT) in diagnostic medicine field, the associated ionizing radiation is still a major concern considering that it may cause genetic and cancerous diseases. Decreasing the exposure…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Ti Bai , Dan Nguyen , Biling Wang , Steve Jiang

Computed Tomography (CT) is a vital diagnostic tool in clinical practice, yet the health risks associated with ionizing radiation cannot be overlooked. Low-dose CT (LDCT) helps mitigate radiation exposure but simultaneously leads to reduced…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Guoliang Gong , Man Yu

Background: Dual-energy CT (DECT) and material decomposition play vital roles in quantitative medical imaging. However, the decomposition process may suffer from significant noise amplification, leading to severely degraded image…

Portable CT scanners enable early stroke detection in prehospital and low-resource settings but require reduced radiation doses, introducing noise that degrades diagnostic reliability. We present a deep learning framework for stroke…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Rhea Ghosal , Ronok Ghosal , Eileen Lou

Computed tomography (CT) is routinely used for three-dimensional non-invasive imaging. Numerous data-driven image denoising algorithms were proposed to restore image quality in low-dose acquisitions. However, considerably less research…

The dose of X-ray radiation and the scanning time are crucial factors in computed tomography (CT) for clinical applications. In this work, we introduce a multi-source static CT imaging system designed to rapidly acquire sparse view and…

Medical Physics · Physics 2025-01-03 Ziju Shen , Haimiao Zhang , Bin Dong , Jun Qiu , Yunxiang Li , Zhili Cui

Noise and artifacts during computed tomography (CT) scans are a fundamental challenge affecting disease diagnosis. However, current methods either involve excessively long reconstruction times or rely on data-driven models for optimization,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Guoquan Wei , Liu Shi , Shaoyu Wang , Mohan Li , Cunfeng Wei , Qiegen Liu

Computed tomography (CT) involves a patient's exposure to ionizing radiation. To reduce the radiation dose, we can either lower the X-ray photon count or down-sample projection views. However, either of the ways often compromises image…

Image and Video Processing · Electrical Eng. & Systems 2023-10-12 Wenjun Xia , Yongyi Shi , Chuang Niu , Wenxiang Cong , Ge Wang

The resurgence of deep neural networks has created an alternative pathway for low-dose computed tomography denoising by learning a nonlinear transformation function between low-dose CT (LDCT) and normal-dose CT (NDCT) image pairs. However,…

Image and Video Processing · Electrical Eng. & Systems 2022-11-04 Sutanu Bera , Prabir Kumar Biswas

Photon-counting CT (PCCT) offers improved diagnostic performance through better spatial and energy resolution, but developing high-quality image reconstruction methods that can deal with these large datasets is challenging. Model-based…

Medical Physics · Physics 2022-08-09 Alma Eguizabal , Ozan Öktem , Mats U. Persson

Limited data and low dose constraints are common problems in a variety of tomographic reconstruction paradigms which lead to noisy and incomplete data. Over the past few years sinogram denoising has become an essential pre-processing step…

Computer Vision and Pattern Recognition · Computer Science 2016-03-15 Faisal Mahmood , Nauman Shahid , Pierre Vandergheynst , Ulf Skoglund

Commercial iterative reconstruction techniques on modern CT scanners target radiation dose reduction but there are lingering concerns over their impact on image appearance and low contrast detectability. Recently, machine learning,…

Computer Vision and Pattern Recognition · Computer Science 2019-07-16 Hongming Shan , Atul Padole , Fatemeh Homayounieh , Uwe Kruger , Ruhani Doda Khera , Chayanin Nitiwarangkul , Mannudeep K. Kalra , Ge Wang

Computed tomography (CT) is a popular medical imaging modality in clinical applications. At the same time, the x-ray radiation dose associated with CT scans raises public concerns due to its potential risks to the patients. Over the past…

Computer Vision and Pattern Recognition · Computer Science 2018-08-13 Chenyu You , Qingsong Yang , Hongming Shan , Lars Gjesteby , Guang Li , Shenghong Ju , Zhuiyang Zhang , Zhen Zhao , Yi Zhang , Wenxiang Cong , Ge Wang

Low-dose CT (LDCT) imaging is desirable in many clinical applications to reduce X-ray radiation dose to patients. Inspired by deep learning (DL), a recent promising direction of model-based iterative reconstruction (MBIR) methods for LDCT…

Image and Video Processing · Electrical Eng. & Systems 2021-02-18 Qiaoqiao Ding , Yuesong Nan , Hao Gao , Hui Ji

Low-dose computed tomography (LDCT) scans, which can effectively alleviate the radiation problem, will degrade the imaging quality. In this paper, we propose a novel LDCT reconstruction network that unrolls the iterative scheme and performs…

Image and Video Processing · Electrical Eng. & Systems 2020-08-04 Wenjun Xia , Zexin Lu , Yongqiang Huang , Zuoqiang Shi , Yan Liu , Hu Chen , Yang Chen , Jiliu Zhou , Yi Zhang

Low-dose CT (LDCT) reduces radiation exposure but introduces protocol-dependent noise and artifacts that vary across institutions. While federated learning enables collaborative training without centralizing patient data, existing methods…

Image and Video Processing · Electrical Eng. & Systems 2026-03-17 Anas Zafar , Muhammad Waqas , Amgad Muneer , Rukhmini Bandyopadhyay , Jia Wu

Limited-angle computed tomography (LACT) offers improved temporal resolution and reduced radiation dose for cardiac imaging, but suffers from severe artifacts due to truncated projections. To address the ill-posedness of LACT…

Computer Vision and Pattern Recognition · Computer Science 2026-03-30 Yu Shi , Shuyi Fan , Changsheng Fang , Shuo Han , Haodong Li , Li Zhou , Bahareh Morovati , Dayang Wang , Hengyong Yu

Noise in low-dose computed tomography (LDCT) can obscure important diagnostic details. While deep learning offers powerful denoising, supervised methods require impractical paired data, and self-supervised alternatives often use opaque,…

Image and Video Processing · Electrical Eng. & Systems 2026-02-19 Yipeng Sun , Linda-Sophie Schneider , Siyuan Mei , Jinhua Wang , Ge Hu , Mingxuan Gu , Chengze Ye , Fabian Wagner , Lan Song , Siming Bayer , Andreas Maier

Utilizing a low-dose CT approach significantly reduces the radiation exposure for patients, yet it introduces challenges, such as increased noise and artifacts in the resultant images, which can hinder accurate medical diagnostics.…

Image and Video Processing · Electrical Eng. & Systems 2024-04-03 Helena Shawn , Thompson Chyrikov , Jacob Lanet , Lam-chi Chen , Jim Zhao , Christina Chajo