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We introduce an explainability method for biomedical hypothesis generation systems, built on top of the novel Hypothesis Generation Context Retriever framework. Our approach combines semantic graph-based retrieval and relevant…

Information Retrieval · Computer Science 2025-11-11 Ilya Tyagin , Saeideh Valipour , Aliaksandra Sikirzhytskaya , Michael Shtutman , Ilya Safro

LongRecall. The completeness of machine-generated text, ensuring that it captures all relevant information, is crucial in domains such as medicine and law and in tasks like list-based question answering (QA), where omissions can have…

Computation and Language · Computer Science 2025-08-22 MohamamdJavad Ardestani , Ehsan Kamalloo , Davood Rafiei

Large language models (LLMs) are gaining increasing interests to improve clinical efficiency for medical diagnosis, owing to their unprecedented performance in modelling natural language. Ensuring the safe and reliable clinical…

Computation and Language · Computer Science 2024-03-26 Lei Liu , Xiaoyan Yang , Fangzhou Li , Chenfei Chi , Yue Shen , Shiwei Lyu Ming Zhang , Xiaowei Ma , Xiangguo Lyu , Liya Ma , Zhiqiang Zhang , Wei Xue , Yiran Huang , Jinjie Gu

The growing volume of biomedical scholarly document abstracts presents an increasing challenge in efficiently retrieving accurate and relevant information. To address this, we introduce a novel approach that integrates an optimized topic…

Computation and Language · Computer Science 2024-11-04 Parvez Zamil , Gollam Rabby , Md. Sadekur Rahman , Sören Auer

Generalization to unseen concepts is a central challenge due to the scarcity of human annotations in Mention-agnostic Biomedical Concept Recognition (MA-BCR). This work makes two key contributions to systematically address this issue.…

Methods to ensure factual accuracy of text generated by large language models (LLM) in clinical medicine are lacking. VeriFact is an artificial intelligence system that combines retrieval-augmented generation and LLM-as-a-Judge to verify…

Large language models (LLMs) have emerged as powerful tools for analyzing complex datasets. Recent studies demonstrate their potential to generate useful, personalized responses when provided with patient-specific health information that…

Large language models (LLMs) present a promising yet challenging frontier for automated source citation in scientific communication. Previous approaches to citation generation have been limited by citation ambiguity and LLM…

Computation and Language · Computer Science 2025-04-14 Yash Saxena , Deepa Tilwani , Ali Mohammadi , Edward Raff , Amit Sheth , Srinivasan Parthasarathy , Manas Gaur

Large language models (LLMs) bring unprecedented flexibility in defining and executing complex, creative natural language generation (NLG) tasks. Yet, this flexibility brings new challenges, as it introduces new degrees of freedom in…

Computation and Language · Computer Science 2024-07-08 Furkan Şahinuç , Ilia Kuznetsov , Yufang Hou , Iryna Gurevych

Conventional biomedical research is increasingly labor-intensive due to the exponential growth of scientific literature and datasets. Artificial intelligence (AI), particularly Large Language Models (LLMs), has the potential to…

Multiagent Systems · Computer Science 2025-07-08 Yi Luo , Linghang Shi , Yihao Li , Aobo Zhuang , Yeyun Gong , Ling Liu , Chen Lin

In retrieval-augmented generation (RAG) question answering systems, generating citations for large language model (LLM) outputs enhances verifiability and helps users identify potential hallucinations. However, we observe two problems in…

Computation and Language · Computer Science 2025-10-21 Guo Chen , Qiuyuan Li , Qiuxian Li , Hongliang Dai , Xiang Chen , Piji Li

Pre-trained language models (LMs) have become ubiquitous in solving various natural language processing (NLP) tasks. There has been increasing interest in what knowledge these LMs contain and how we can extract that knowledge, treating LMs…

Computation and Language · Computer Science 2021-09-16 Mujeen Sung , Jinhyuk Lee , Sean Yi , Minji Jeon , Sungdong Kim , Jaewoo Kang

Large language models (LLMs) are increasingly evident for accurate question answering across various domains. However, rigorous evaluation of their performance on complex question-answering (QA) capabilities is essential before deployment…

Computation and Language · Computer Science 2025-09-03 Reem Abdel-Salam , Mary Adewunmi , Modinat A. Abayomi

Ensuring the verifiability of model answers is a fundamental challenge for retrieval-augmented generation (RAG) in the question answering (QA) domain. Recently, self-citation prompting was proposed to make large language models (LLMs)…

Computation and Language · Computer Science 2024-12-02 Jirui Qi , Gabriele Sarti , Raquel Fernández , Arianna Bisazza

Unlocking deep and interpretable biological reasoning from complex genomic data remains a major AI challenge limiting scientific progress. While current DNA foundation models excel at representing sequences, they struggle with multi-step…

Doctors and patients alike increasingly use Large Language Models (LLMs) to diagnose clinical cases. However, unlike domains such as math or coding, where correctness can be objectively defined by the final answer, medical diagnosis…

Computation and Language · Computer Science 2025-05-21 Kevin Wu , Eric Wu , Rahul Thapa , Kevin Wei , Angela Zhang , Arvind Suresh , Jacqueline J. Tao , Min Woo Sun , Alejandro Lozano , James Zou

Ever-expanding volumes of biomedical text require automated semantic annotation techniques to curate and put to best use. An established field of research seeks to link mentions in text to knowledge bases such as those included in the UMLS…

Artificial Intelligence · Computer Science 2018-11-13 Genevieve Gorrell , Xingyi Song , Angus Roberts

Citation quality is crucial in information-seeking systems, directly influencing trust and the effectiveness of information access. Current evaluation frameworks, both human and automatic, mainly rely on Natural Language Inference (NLI) to…

Computation and Language · Computer Science 2025-06-03 Yumo Xu , Peng Qi , Jifan Chen , Kunlun Liu , Rujun Han , Lan Liu , Bonan Min , Vittorio Castelli , Arshit Gupta , Zhiguo Wang

Evaluating LLM-generated text has become a key challenge, especially in domain-specific contexts like the medical field. This work introduces a novel evaluation methodology for LLM-generated medical explanatory arguments, relying on Proxy…

Computation and Language · Computer Science 2024-10-01 Iker De la Iglesia , Iakes Goenaga , Johanna Ramirez-Romero , Jose Maria Villa-Gonzalez , Josu Goikoetxea , Ander Barrena

Misinformation in healthcare, from vaccine hesitancy to unproven treatments, poses risks to public health and trust in medical systems. While machine learning and natural language processing have advanced automated fact-checking, validating…

Computation and Language · Computer Science 2025-09-18 Mariano Barone , Antonio Romano , Giuseppe Riccio , Marco Postiglione , Vincenzo Moscato