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In this paper, we present MCBench, a benchmark suite designed to assess the quality of Monte Carlo (MC) samples. The benchmark suite enables quantitative comparisons of samples by applying different metrics, including basic statistical…

Long-read sequencing (LRS) is able to simultaneously capture information about both DNA sequence and modifications, such as CpG methylation in a single sequencing experiment. Here we present Methylation Operation Wizard (MeOW), a program to…

Genomics · Quantitative Biology 2024-02-28 Miranda PG Zalusky , Danny E Miller

DNA methylation (DNAme) is a critical component of the epigenetic regulatory machinery and aberrations in DNAme patterns occur in many diseases, such as cancer. Mapping and understanding DNAme profiles offers considerable promise for…

Multilevel linear models allow flexible statistical modelling of complex data with different levels of stratification. Identifying the most appropriate model from the large set of possible candidates is a challenging problem. In the…

Methodology · Statistics 2022-11-15 Tom Edinburgh , Ari Ercole , Stephen J. Eglen

Advances in digital sensors, digital data storage and communications have resulted in systems being capable of accumulating large collections of data. In the light of dealing with the challenges that massive data present, this work proposes…

Computation · Statistics 2015-12-09 Allan De Freitas , François Septier , Lyudmila Mihaylova

A Bayesian re-analysis of published radial velocity data sets is providing evidence for additional planetary candidates. The nonlinear model fitting is accomplished with a new hybrid Markov chain Monte Carlo (HMCMC) algorithm which…

Earth and Planetary Astrophysics · Physics 2009-02-13 P. C. Gregory

Bayesian inference using Markov Chain Monte Carlo (MCMC) on large datasets has developed rapidly in recent years. However, the underlying methods are generally limited to relatively simple settings where the data have specific forms of…

Methodology · Statistics 2020-02-18 Robert Salomone , Matias Quiroz , Robert Kohn , Mattias Villani , Minh-Ngoc Tran

In this work, we propose a two-stage algorithm based on Bayesian modeling and computation aiming at quantifying analyte concentrations or quantities in complex mixtures with Raman spectroscopy. A hierarchical Bayesian model is built for…

Applications · Statistics 2018-05-22 Ningren Han , Rajeev J. Ram

In this article, we study the application of Multi-Level Monte Carlo (MLMC) approaches to numerical random homogenization. Our objective is to compute the expectation of some functionals of the homogenized coefficients, or of the…

Numerical Analysis · Mathematics 2013-01-15 Yalchin Efendiev , Cornelia Kronsbein , Frederic Legoll

With the rising prevalence of deepfakes, there is a growing interest in developing generalizable detection methods for various types of deepfakes. While effective in their specific modalities, traditional detection methods fall short in…

Computer Vision and Pattern Recognition · Computer Science 2024-05-01 Cai Yu , Shan Jia , Xiaomeng Fu , Jin Liu , Jiahe Tian , Jiao Dai , Xi Wang , Siwei Lyu , Jizhong Han

Cell detection and cell type classification from biomedical images play an important role for high-throughput imaging and various clinical application. While classification of single cell sample can be performed with standard computer…

Image and Video Processing · Electrical Eng. & Systems 2019-12-17 Wei Qiu , Jiaming Guo , Xiang Li , Mengjia Xu , Mo Zhang , Ning Guo , Quanzheng Li

We developed a low-cost, high-throughput microbiome profiling method that uses combinatorial sequence tags attached to PCR primers that amplify the rRNA V6 region. Amplified PCR products are sequenced using an Illumina paired-end protocol…

Accurate segmentation of coronary arteries is a pivotal process in assessing cardiovascular diseases. However, the intricate structure of the cardiovascular system presents significant challenges for automatic segmentation, especially when…

Image and Video Processing · Electrical Eng. & Systems 2023-11-20 Jonghoe Ku , Yong-Hee Lee , Junsup Shin , In Kyu Lee , Hyun-Woo Kim

Detecting the newly emerging malware variants in real time is crucial for mitigating cyber risks and proactively blocking intrusions. In this paper, we propose MG-DVD, a novel detection framework based on dynamic heterogeneous graph…

Cryptography and Security · Computer Science 2021-06-25 Chen Liu , Bo Li , Jun Zhao , Ming Su , Xu-Dong Liu

In the 20+ years of Doppler observations of stars, scientists have uncovered a diverse population of extrasolar multi-planet systems. A common technique for characterizing the orbital elements of these planets is Markov chain Monte Carlo…

Earth and Planetary Astrophysics · Physics 2015-06-18 Benjamin E. Nelson , Eric B. Ford , Matthew J. Payne

Mitosis nuclei count is one of the important indicators for the pathological diagnosis of breast cancer. The manual annotation needs experienced pathologists, which is very time-consuming and inefficient. With the development of deep…

Computer Vision and Pattern Recognition · Computer Science 2022-12-29 Huadeng Wang , Zhipeng Liu , Rushi Lan , Zhenbing Liu , Xiaonan Luo , Xipeng Pan , Bingbing Li

The presence of MGMT promoter methylation significantly affects how well chemotherapy works for patients with Glioblastoma Multiforme (GBM). Currently, confirmation of MGMT promoter methylation relies on invasive brain tumor tissue…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Rawan Alyahya , Asrar Alruwayqi , Atheer Alqarni , Asma Alkhaldi , Metab Alkubeyyer , Xin Gao , Mona Alshahrani

We introduce a revised derivation of the bitwise Markov Chain Monte Carlo (MCMC) multiple-input multiple-output (MIMO) detector. The new approach resolves the previously reported high SNR stalling problem of MCMC without the need for…

Information Theory · Computer Science 2017-07-13 Jonathan C. Hedstrom , Chung Him , Yuen , Rong-Rong Chen , Behrouz Farhang-Boroujeny

In this article, we describe a {\tt R} package for sampling from an empirical likelihood-based posterior using a Hamiltonian Monte Carlo method. Empirical likelihood-based methodologies have been used in Bayesian modeling of many problems…

Other Statistics · Statistics 2022-09-07 Dang Trung Kien , Neo Han Wei , Sanjay Chaudhuri

Microstructure of materials is often characterized through image analysis to understand processing-structure-properties linkages. We propose a largely automated framework that integrates unsupervised and supervised learning methods to…

Applications · Statistics 2025-09-05 Kungang Zhang , Wei Chen , Wing K. Liu , L. Catherine Brinson , Daniel W. Apley
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