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Modern cancer genomics datasets involve widely varying sizes and scales, measurement variables, and correlation structures. A fundamental analytical goal in these high-throughput studies is the development of general statistical techniques…

Methodology · Statistics 2022-04-12 Chiyu Gu , Veerabhadran Baladandayuthapani , Subharup Guha

Multi-stage (designed) procedures, obtained by splitting the sampling budget suitably across stages, and designing the sampling at a particular stage based on information about the parameter obtained from previous stages, are often…

Methodology · Statistics 2014-01-08 Atul Mallik , Moulinath Banerjee , George Michailidis

For large model spaces, the potential entrapment of Markov chain Monte Carlo (MCMC) based methods with spike-and-slab priors poses significant challenges in posterior computation in regression models. On the other hand, maximum a posteriori…

Methodology · Statistics 2026-02-25 Shamriddha De , Joyee Ghosh

Scientific literature contains large volumes of complex, unstructured figures that are compound in nature (i.e. composed of multiple images, graphs, and drawings). Separation of these compound figures is critical for information retrieval…

Computer Vision and Pattern Recognition · Computer Science 2021-10-08 Weixin Jiang , Eric Schwenker , Trevor Spreadbury , Nicola Ferrier , Maria K. Y. Chan , Oliver Cossairt

Radio signal recognition is a crucial function in electronic warfare. Precise identification and localisation of radar pulse activities are required by electronic warfare systems to produce effective countermeasures. Despite the importance…

Machine Learning · Computer Science 2023-12-18 Zi Huang , Akila Pemasiri , Simon Denman , Clinton Fookes , Terrence Martin

The R package MixMashNet provides an integrated framework for estimating and analyzing single and multilayer networks using Mixed Graphical Models (MGMs), accommodating continuous, count, and categorical variables. In the multilayer…

Bayesian phylogenetic inference is currently done via Markov chain Monte Carlo (MCMC) with simple proposal mechanisms. This hinders exploration efficiency and often requires long runs to deliver accurate posterior estimates. In this paper,…

Machine Learning · Statistics 2024-05-24 Cheng Zhang , Frederick A. Matsen

The combinatorial sequential Monte Carlo (CSMC) has been demonstrated to be an efficient complementary method to the standard Markov chain Monte Carlo (MCMC) for Bayesian phylogenetic tree inference using biological sequences. It is…

Computation · Statistics 2020-08-12 Shijia Wang , Liangliang Wang

Investigating critical phenomena or phase transitions is of high interest in physics and chemistry, for which Monte Carlo (MC) simulations, a crucial tool for numerically analyzing macroscopic properties of given systems, are often hindered…

Machine Learning · Computer Science 2025-09-09 Ankur Singha , Elia Cellini , Kim A. Nicoli , Karl Jansen , Stefan Kühn , Shinichi Nakajima

We introduce an R package, PCMBase, to rapidly calculate the likelihood for multivariate phylogenetic comparative methods. The package is not specific to particular models but offers the user the functionality to very easily implement a…

Populations and Evolution · Quantitative Biology 2019-12-13 Venelin Mitov , Krzysztof Bartoszek , Georgios Asimomitis , Tanja Stadler

We consider a Bayesian functional data analysis for observations measured as extremely long sequences. Splitting the sequence into a number of small windows with manageable length, the windows may not be independent especially when they are…

Methodology · Statistics 2021-12-10 Suvo Chatterjee , Shrabanti Chowdhury , Duchwan Ryu , Sanjib Basu

The hierarchical Dirichlet process (HDP) has become an important Bayesian nonparametric model for grouped data, such as document collections. The HDP is used to construct a flexible mixed-membership model where the number of components is…

Machine Learning · Statistics 2012-01-10 Chong Wang , David M. Blei

To better detect pedestrians of various scales, deep multi-scale methods usually detect pedestrians of different scales by different in-network layers. However, the semantic levels of features from different layers are usually inconsistent.…

Computer Vision and Pattern Recognition · Computer Science 2018-04-04 Jiale Cao , Yanwei Pang , Xuelong Li

An approach for multiplex qualitative and quantitative microarray-based PCR analysis has been proposed. The characteristics of PCR executed on a gel-based oligonucleotide microarray with immobilized forward primers and a single common…

Quantitative Methods · Quantitative Biology 2009-01-22 Natalia V Zakharova , Alexei L Drobyshev , Dmitry A Khodakov , Anna I Myznikova , Irina A Gorban

Recently, Fully Convolutional Network (FCN) seems to be the go-to architecture for image segmentation, including semantic scene parsing. However, it is difficult for a generic FCN to discriminate pixels around the object boundaries, thus…

Computer Vision and Pattern Recognition · Computer Science 2020-04-22 Pingping Zhang , Wei Liu , Yinjie Lei , Hongyu Wang , Huchuan Lu

Malware is a significant threat to the security of computer systems and networks which requires sophisticated techniques to analyze the behavior and functionality for detection. Traditional signature-based malware detection methods have…

Cryptography and Security · Computer Science 2023-06-22 Shaswata Mitra , Stephen A. Torri , Sudip Mittal

This paper proposes a Bayesian framework for localization of multiple sources in the event of accidental hazardous contaminant release. The framework assimilates sensor measurements of the contaminant concentration with an integrated…

Applications · Statistics 2018-10-18 Young-Jin Park , Piyush M. Tagade , Han-Lim Choi

Multimodal manifold modeling methods extend the spectral geometry-aware data analysis to learning from several related and complementary modalities. Most of these methods work based on two major assumptions: 1) there are the same number of…

Machine Learning · Computer Science 2021-05-13 Maysam Behmanesh , Peyman Adibi , Jocelyn Chanussot , Sayyed Mohammad Saeed Ehsani

Accurately predicting chronological age from DNA methylation patterns is crucial for advancing biological age estimation. However, this task is made challenging by Epigenetic Correlation Drift (ECD) and Heterogeneity Among CpGs (HAC), which…

Genomics · Quantitative Biology 2025-01-07 Zipeng Wu , Daniel Herring , Fabian Spill , James Andrews

Identifying disease-associated changes in DNA methylation can help to gain a better understanding of disease etiology. Bisulfite sequencing technology allows the generation of methylation profiles at single base of DNA. We previously…