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In this paper, we propose a new Semi-Nonnegative Matrix Factorization method for 2-dimensional (2D) data, named TS-NMF. It overcomes the drawback of existing methods that seriously damage the spatial information of the data by converting 2D…

Machine Learning · Computer Science 2020-05-20 Chong Peng , Zhilu Zhang , Zhao Kang , Chenglizhao Chen , Qiang Cheng

Spatial-Spectral Mamba (SSM) improves computational efficiency and captures long-range dependencies, addressing Transformer limitations. However, traditional Mamba models overlook rich spectral information in HSIs and struggle with high…

Computer Vision and Pattern Recognition · Computer Science 2025-02-07 Muhammad Ahmad , Muhammad Hassaan Farooq Butt , Muhammad Usama , Hamad Ahmed Altuwaijri , Manuel Mazzara , Salvatore Distefano

Convolutional Neural Networks (CNNs) are the predominant model used for a variety of medical image analysis tasks. At inference time, these models are computationally intensive, especially with volumetric data. In principle, it is possible…

Computer Vision and Pattern Recognition · Computer Science 2023-06-30 Jose Javier Gonzalez Ortiz , John Guttag , Adrian Dalca

Spatial transcriptomics (ST) reveals spatial heterogeneity of gene expression, yet its resolution is limited by current platforms. Recent methods enhance resolution via H&E-stained histology, but three major challenges persist: (1)…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Xuepeng Liu , Zheng Jiang , Pinan Zhu , Hanyu Liu , Chao Li

Integrating a low-spatial-resolution hyperspectral image (LR-HSI) with a high-spatial-resolution multispectral image (HR-MSI) is recognized as a valid method for acquiring HR-HSI. Among the current fusion approaches, the tensor ring (TR)…

Image and Video Processing · Electrical Eng. & Systems 2023-10-17 Jun Zhang , Lipeng Zhu , Chao Wang , Shutao Li

Full-field ultra-high-speed (UHS) x-ray imaging experiments have been well established to characterize various processes and phenomena. However, the potential of UHS experiments through the joint acquisition of x-ray videos with distinct…

Image and Video Processing · Electrical Eng. & Systems 2024-11-28 Songyuan Tang , Tekin Bicer , Tao Sun , Kamel Fezzaa , Samuel J. Clark

Recent advancements in transformers, specifically self-attention mechanisms, have significantly improved hyperspectral image (HSI) classification. However, these models often suffer from inefficiencies, as their computational complexity…

Cells in multicellular organisms coordinate to form structural and functional niches. With spatial transcriptomics (ST) enabling gene expression profiling in spatial contexts, it has been revealed that spatial niches serve as cohesive and…

Quantitative Methods · Quantitative Biology 2026-05-26 Mo Chen , Minsheng Hao , Xinquan Liu , Lin Deng , Peng Liu , Chen Li , Dongfang Wang , Kui Hua , Liang Guo , Xuegong Zhang , Lei Wei

Miniscope calcium imaging is increasingly being used to monitor large populations of neuronal activities in freely behaving animals. However, due to the high background and low signal-to-noise ratio of the single-photon based imaging used…

Neurons and Cognition · Quantitative Biology 2017-04-05 Jinghao Lu , Chunyuan Li , Fan Wang

Calcium imaging has revolutionized systems neuroscience, providing the ability to image large neural populations with single-cell resolution. The resulting datasets are quite large, which has presented a barrier to routine open sharing of…

We introduce a new method based on nonnegative matrix factorization, Neural NMF, for detecting latent hierarchical structure in data. Datasets with hierarchical structure arise in a wide variety of fields, such as document classification,…

Machine Learning · Computer Science 2023-03-02 Tyler Will , Runyu Zhang , Eli Sadovnik , Mengdi Gao , Joshua Vendrow , Jamie Haddock , Denali Molitor , Deanna Needell

Radiotherapy (RT) combined with cetuximab is the standard treatment for patients with inoperable head and neck cancers. Segmentation of head and neck (H&N) tumors is a prerequisite for radiotherapy planning but a time-consuming process. In…

Image and Video Processing · Electrical Eng. & Systems 2023-10-16 Gary Y. Li , Junyu Chen , Se-In Jang , Kuang Gong , Quanzheng Li

Denoising is a crucial preprocessing step for hyperspectral images (HSIs) due to noise arising from intra-imaging mechanisms and environmental factors. Long-range spatial-spectral correlation modeling is beneficial for HSI denoising but…

Image and Video Processing · Electrical Eng. & Systems 2024-08-06 Guanyiman Fu , Fengchao Xiong , Jianfeng Lu , Jun Zhou

Magnetic Resonance Fingerprinting (MRF) reconstructs tissue maps based on a sequence of very highly undersampled images. In order to be able to perform MRF reconstruction, state-of-the-art MRF methods rely on priors such as the MR physics…

Image and Video Processing · Electrical Eng. & Systems 2020-10-20 Simon Arberet , Xiao Chen , Boris Mailhe , Peter Speier , Gregor Koerzdoerfer , Mathias Nittka , Heiko Meyer , Mariappan S. Nadar

Spatial transcriptomics (ST) has emerged as a powerful technology for bridging histology imaging with gene expression profiling. However, its application has been limited by low throughput and the need for specialized experimental…

Computer Vision and Pattern Recognition · Computer Science 2025-06-09 Tinglin Huang , Tianyu Liu , Mehrtash Babadi , Wengong Jin , Rex Ying

Medical Hyperspectral Imaging (MHSI) offers potential for computational pathology and precision medicine. However, existing CNN and Transformer struggle to balance segmentation accuracy and speed due to high spatial-spectral dimensionality.…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Shijie Lin , Boxiang Yun , Wei Shen , Qingli Li , Anqiang Yang , Yan Wang

We propose a radical advance in Magnetic Resonance Imaging. MRI remains slow because it requires successive applications of magnetic field gradients to encode for spatial location. Parallel MRI accelerates imaging by permitting…

Medical Physics · Physics 2018-09-19 Michael Hutchinson , Ulrich Raff , Luis Osorio

The spike camera, with its high temporal resolution, low latency, and high dynamic range, addresses high-speed imaging challenges like motion blur. It captures photons at each pixel independently, creating binary spike streams rich in…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Liangyan Jiang , Chuang Zhu , Yanxu Chen

Medical semantic-mask synthesis boosts data augmentation and analysis, yet most GAN-based approaches still produce one-to-one images and lack spatial consistency in complex scans. To address this, we propose AnatoMaskGAN, a novel synthesis…

Image and Video Processing · Electrical Eng. & Systems 2025-08-18 Zonglin Wu , Yule Xue , Qianxiang Hu , Yaoyao Feng , Yuqi Ma , Shanxiong Chen

Terahertz (THz) extremely large-scale MIMO (XL-MIMO) is considered a key enabling technology for 6G and beyond due to its advantages such as wide bandwidth and high beam gain. As the frequency and array size increase, users are more likely…

Signal Processing · Electrical Eng. & Systems 2025-05-15 Huixin Xu , Jianhua Zhang , Pan Tang , Hongbo Xing , Chong Han , Lei Tian , Qixing Wang , Guangyi Liu