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Spatial transcriptomics data analysis integrates cellular transcriptional activity with spatial coordinates to identify spatial domains, infer cell-type dynamics, and characterize gene expression patterns within tissues. Despite recent…

Quantitative Methods · Quantitative Biology 2026-03-25 Sean Cottrell , Guo-Wei Wei , Longxiu Huang

Hypertension is a heterogeneous syndrome in need of improved subtyping using phenotypic and genetic measurements so that patients in different subtypes share similar pathophysiologic mechanisms and respond more uniformly to targeted…

Quantitative Methods · Quantitative Biology 2018-05-22 Yuan Luo , Chengsheng Mao , Yiben Yang , Fei Wang , Faraz S. Ahmad , Donna Arnett , Marguerite R. Irvin , Sanjiv J. Shah

Distributed microphone arrays composed of multiple subarrays enable blind source separation over a wide spatial area. Directly applying fast multichannel nonnegative matrix factorization (FastMNMF) to all subarrays can exploit observations…

Audio and Speech Processing · Electrical Eng. & Systems 2026-05-20 Hirotaka Nishikori , Nobutaka Ito , Kouei Yamaoka , Norihiro Takamune , Hiroshi Saruwatari

The advent of next-generation sequencing-based spatially resolved transcriptomics (SRT) techniques has transformed genomic research by enabling high-throughput gene expression profiling while preserving spatial context. Identifying spatial…

Methodology · Statistics 2024-08-27 Bencong Zhu , Guanyu Hu , Xiaodan Fan , Qiwei Li

Deformable image registration is crucial for aligning medical images in a nonlinear fashion across different modalities, allowing for precise spatial correspondence between varying anatomical structures. This paper presents NestedMorph, a…

Image and Video Processing · Electrical Eng. & Systems 2024-12-11 Gurucharan Marthi Krishna Kumar , Janine Mendola , Amir Shmuel

Symmetric nonnegative matrix factorization (SymNMF) is a powerful tool for clustering, which typically uses the $k$-nearest neighbor ($k$-NN) method to construct similarity matrix. However, $k$-NN may mislead clustering since the neighbors…

Machine Learning · Computer Science 2024-12-06 Wenlong Lyu , Yuheng Jia

Magnetic resonance imaging (MRI) is an important non-invasive clinical tool that can produce high-resolution and reproducible images. However, a long scanning time is required for high-quality MR images, which leads to exhaustion and…

Image and Video Processing · Electrical Eng. & Systems 2022-04-12 Jiahao Huang , Yingying Fang , Yinzhe Wu , Huanjun Wu , Zhifan Gao , Yang Li , Javier Del Ser , Jun Xia , Guang Yang

Nonnegative matrix factorization (NMF) is a linear dimensionality technique for nonnegative data with applications such as image analysis, text mining, audio source separation and hyperspectral unmixing. Given a data matrix $M$ and a…

Machine Learning · Computer Science 2021-04-14 Junjun Pan , Nicolas Gillis

In this paper, we propose a novel method for image fusion with a high-resolution panchromatic image and a low-resolution multispectral image at the same geographical location. The fusion is formulated as a convex optimization problem which…

Computer Vision and Pattern Recognition · Computer Science 2015-10-28 Chen Chen , Yeqing Li , Wei Liu , Junzhou Huang

The extent to which different neural or artificial neural networks (models) rely on equivalent representations to support similar tasks remains a central question in neuroscience and machine learning. Prior work has typically compared…

Neurons and Cognition · Quantitative Biology 2026-04-06 Jialin Wu , Shreya Saha , Yiqing Bo , Meenakshi Khosla

Spatial transcriptomics has revolutionized tissue analysis by simultaneously mapping gene expression, spatial topography, and histological context across consecutive tissue sections, enabling systematic investigation of spatial…

Applications · Statistics 2025-10-24 Meng Zhou , Shuangge Ma , Mengyun Wu

NeRF-based SLAM has recently achieved promising results in tracking and reconstruction. However, existing methods face challenges in providing sufficient scene representation, capturing structural information, and maintaining global…

Computer Vision and Pattern Recognition · Computer Science 2025-03-28 Ziren Gong , Fabio Tosi , Youmin Zhang , Stefano Mattoccia , Matteo Poggi

Spatial transcriptomics (ST) has revolutionised transcriptomics analysis by preserving tissue architecture, allowing researchers to study gene expression in its native spatial context. However, despite its potential, ST still faces…

Quantitative Methods · Quantitative Biology 2025-05-19 Anthony Baptista , Rosamond Nuamah , Ciro Chiappini , Anita Grigoriadis

Delineating the brain tumor from magnetic resonance (MR) images is critical for the treatment of gliomas. However, automatic delineation is challenging due to the complex appearance and ambiguous outlines of tumors. Considering that…

Image and Video Processing · Electrical Eng. & Systems 2020-11-03 Chenyu Liu , Wangbin Ding , Lei Li , Zhen Zhang , Chenhao Pei , Liqin Huang , Xiahai Zhuang

This work presents a robust multi-class classification framework for handwritten digits that combines diffusion-driven feature denoising with a hybrid feature representation. Inspired by our previous work on brain tumor classification, the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Hiba Adil Al-kharsan , Róbert Rajkó

Integrating CNNs and RNNs to capture spatiotemporal dependencies is a prevalent strategy for spatiotemporal prediction tasks. However, the property of CNNs to learn local spatial information decreases their efficiency in capturing…

Computer Vision and Pattern Recognition · Computer Science 2023-12-27 Song Tang , Chuang Li , Pu Zhang , RongNian Tang

Nonnegative matrix factorization (NMF) methods have proved to be powerful across a wide range of real-world clustering applications. Integrating multiple types of measurements for the same objects/subjects allows us to gain a deeper…

Machine Learning · Computer Science 2014-09-16 Daniel Hidru , Anna Goldenberg

Convolutional neural networks (CNNs) have been applied to learn spatial features for high-resolution (HR) synthetic aperture radar (SAR) image classification. However, there has been little work on integrating the unique statistical…

Computer Vision and Pattern Recognition · Computer Science 2022-05-04 Wenkai Liang , Yan Wu , Ming Li , Peng Zhang , Yice Cao , Xin Hu

We introduce the Normalized Matching Transformer (NMT), a deep learning approach for efficient and accurate sparse semantic keypoint matching between image pairs. NMT consists of a strong visual backbone, geometric feature refinement via…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Abtin Pourhadi , Paul Swoboda

Deep learning-based nuclei segmentation and classification in pathology images typically rely on large-scale pixel-level manual annotations, which are costly and difficult to obtain across diverse tissues and staining conditions. To address…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Kazuya Nishimura , Ryoma Bise , Haruka Hirose , Yasuhiro Kojima
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