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Accurate 3D medical image segmentation requires a delicate balance between fine-grained local details and global contextual understanding. While spatial-domain models often struggle with long-range dependencies, existing frequency-based…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Bo Zhang , Yifan Zhang , Shuo Yan , Yu Bai , Zheng Zhang , Wu Liu , Wendong Wang , Yongdong Zhang

Spatial transcriptomics (ST) enables mapping gene expression with spatial context but is severely affected by high sparsity and technical noise, which conceals true biological signals and hinders downstream analyses. To address these…

Machine Learning · Computer Science 2026-03-10 Sayeem Bin Zaman , Fahim Hafiz , Riasat Azim

The success of self-attention (SA) in Transformer demonstrates the importance of non-local information to image super-resolution (SR), but the huge computing power required makes it difficult to implement lightweight models. To solve this…

Image and Video Processing · Electrical Eng. & Systems 2025-08-18 Yinggan Tang , Quanwei Hu

Spatial proteomics maps protein distributions in tissues, providing transformative insights for life sciences. However, current sequencing-based technologies suffer from low spatial resolution, and substantial inter-tissue variability in…

Quantitative Methods · Quantitative Biology 2025-08-26 Bokai Zhao , Weiyang Shi , Hanqing Chao , Zijiang Yang , Yiyang Zhang , Ming Song , Tianzi Jiang

Spatial transcriptomics enables gene expression profiling with spatial context, offering unprecedented insights into the tissue microenvironment. However, most computational models treat genes as isolated numerical features, ignoring the…

Machine Learning · Computer Science 2025-11-17 Jiangkai Long , Yanran Zhu , Chang Tang , Kun Sun , Yuanyuan Liu , Xuesong Yan

Non-negative matrix factorization (NMF) is an important technique for obtaining low dimensional representations of datasets. However, classical NMF does not take into account data that is collected at different times or in different…

Machine Learning · Computer Science 2023-11-21 James Chapman , Yotam Yaniv , Deanna Needell

The advent of next-generation sequencing-based spatially resolved transcriptomics (SRT) techniques has reshaped genomic studies by enabling high-throughput gene expression profiling while preserving spatial and morphological context.…

Applications · Statistics 2023-12-14 Bencong Zhu , Guanyu Hu , Yang Xie , Lin Xu , Xiaodan Fan , Qiwei Li

Hyperspectral imaging enables fine-grained recognition of materials by capturing rich spectral signatures, but learning robust classifiers is challenging due to high dimensionality, spectral redundancy, limited labeled data, and strong…

Computer Vision and Pattern Recognition · Computer Science 2026-04-20 Alexander Musiat , Nikolas Ebert , Oliver Wasenmüller

In the field of biomedical image analysis, the quest for architectures capable of effectively capturing long-range dependencies is paramount, especially when dealing with 3D image segmentation, classification, and landmark detection.…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Haifan Gong , Luoyao Kang , Yitao Wang , Xiang Wan , Haofeng Li

This study proposes an efficient Densely Swin Hybrid (EDSH) framework for brain tumor MRI analysis, designed to jointly capture fine grained texture patterns and long range contextual dependencies. Two tumor aware experimental setups are…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Muhammad Ali Shah , Muhammad Mansoor Alam , Saddam Hussain Khan

Multimode fibers (MMFs) have the potential to carry complex images for endoscopy and related applications, but decoding the complex speckle patterns produced by mode-mixing and modal dispersion in MMFs is a serious challenge. Several groups…

Image and Video Processing · Electrical Eng. & Systems 2020-09-02 Changyan Zhu , Eng Aik Chan , You Wang , Weina Peng , Ruixiang Guo , Baile Zhang , Cesare Soci , Yidong Chong

Classifying hyperspectral images (HSIs) is a complex task in remote sensing due to the high-dimensional nature and volume of data involved. To address these challenges, we propose the Spectral-Spatial non-Linear Model, a novel framework…

Computer Vision and Pattern Recognition · Computer Science 2024-12-04 Judy X Yang , Jing Wang , Zekun Long , Chenhong Sui , Jun Zhou

Medical image segmentation has achieved remarkable advancements using deep neural networks (DNNs). However, DNNs often need big amounts of data and annotations for training, both of which can be difficult and costly to obtain. In this work,…

Computer Vision and Pattern Recognition · Computer Science 2021-10-19 Hengji Cui , Dong Wei , Kai Ma , Shi Gu , Yefeng Zheng

Effectively modeling global context information in hyperspectral image (HSI) denoising is crucial, but prevailing methods using convolution or transformers still face localized or computational efficiency limitations. Inspired by the…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Yang Liu , Jiahua Xiao , Xiang Song , Yu Guo , Peilin Jiang , Haiwei Yang , Fei Wang

We integrate the recently proposed spatial transformer network (SPN) [Jaderberg et. al 2015] into a recurrent neural network (RNN) to form an RNN-SPN model. We use the RNN-SPN to classify digits in cluttered MNIST sequences. The proposed…

Computer Vision and Pattern Recognition · Computer Science 2015-09-18 Søren Kaae Sønderby , Casper Kaae Sønderby , Lars Maaløe , Ole Winther

This paper describes a versatile method that accelerates multichannel source separation methods based on full-rank spatial modeling. A popular approach to multichannel source separation is to integrate a spatial model with a source model…

Sound · Computer Science 2019-03-11 Kouhei Sekiguchi , Aditya Arie Nugraha , Yoshiaki Bando , Kazuyoshi Yoshii

As we all known, the nonnegative matrix factorization (NMF) is a dimension reduction method that has been widely used in image processing, text compressing and signal processing etc. In this paper, an algorithm for nonnegative matrix…

Numerical Analysis · Mathematics 2013-05-27 Shu-Zhen Lai , Hou-Biao Li , Zu-Tao Zhang

This study introduces SEFI (SEgmentation-Free Integration), a novel method for integrating morphological features of cell nuclei with spatial transcriptomics data. Cell segmentation poses a significant challenge in the analysis of spatial…

Image and Video Processing · Electrical Eng. & Systems 2025-02-21 Eduard Chelebian , Pratiti Dasgupta , Zainalabedin Samadi , Carolina Wählby , Amjad Askary

Aggregating multi-site brain MRI data can enhance deep learning model training, but also introduces non-biological heterogeneity caused by site-specific variations (e.g., differences in scanner vendors, acquisition parameters, and imaging…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Mengqi Wu , Yongheng Sun , Qianqian Wang , Pew-Thian Yap , Mingxia Liu

Spatial Transcriptomics is a novel technology that aligns histology images with spatially resolved gene expression profiles. Although groundbreaking, it struggles with gene capture yielding high corruption in acquired data. Given potential…

Computer Vision and Pattern Recognition · Computer Science 2024-09-30 Gabriel Mejia , Daniela Ruiz , Paula Cárdenas , Leonardo Manrique , Daniela Vega , Pablo Arbeláez