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In this study, we explore the fundamental principles behind the architecture of the human brain's structural connectome, from the perspective of spectral analysis of Laplacian and adjacency matrices. Building on the idea that the brain…

Neurons and Cognition · Quantitative Biology 2024-05-28 Anna Bobyleva , Alexander Gorsky , Sergei Nechaev , Olga Valba , Nikita Pospelov

The emergence of explainability methods has enabled a better comprehension of how deep neural networks operate through concepts that are easily understood and implemented by the end user. While most explainability methods have been designed…

Neurons and Cognition · Quantitative Biology 2022-03-17 Fernanda L. Ribeiro , Steffen Bollmann , Ross Cunnington , Alexander M. Puckett

Estimating a 3D human pose has proven to be a challenging task, primarily because of the complexity of the human body joints, occlusions, and variability in lighting conditions. In this paper, we introduce a higher-order graph convolutional…

Computer Vision and Pattern Recognition · Computer Science 2021-11-02 Jianning Quan , A. Ben Hamza

Resting-state functional magnetic resonance imaging (rs-fMRI) offers a non-invasive approach to examining abnormal brain connectivity associated with brain disorders. Graph neural network (GNN) gains popularity in fMRI representation…

Quantitative Methods · Quantitative Biology 2023-08-22 Junhao Zhang , Qianqian Wang , Xiaochuan Wang , Lishan Qiao , Mingxia Liu

Learning to model and reconstruct humans in clothing is challenging due to articulation, non-rigid deformation, and varying clothing types and topologies. To enable learning, the choice of representation is the key. Recent work uses neural…

Computer Vision and Pattern Recognition · Computer Science 2021-04-16 Qianli Ma , Shunsuke Saito , Jinlong Yang , Siyu Tang , Michael J. Black

Anatomical connectivity imposes strong constraints on brain function, but there is no general agreement about principles that govern its organization. Based on extensive quantitative data we tested the power of three models to predict…

Neurons and Cognition · Quantitative Biology 2016-05-31 Sarah F. Beul , Helen Barbas , Claus C. Hilgetag

Our knowledge of the organisation of the human brain at the population-level is yet to translate into power to predict functional differences at the individual-level, limiting clinical applications, and casting doubt on the generalisability…

Neurons and Cognition · Quantitative Biology 2024-04-04 James K Ruffle , Robert J Gray , Samia Mohinta , Guilherme Pombo , Chaitanya Kaul , Harpreet Hyare , Geraint Rees , Parashkev Nachev

Representation learning on large-scale unstructured volumetric and surface meshes poses significant challenges in neuroimaging, especially when models must incorporate diverse vertex-level morphometric descriptors, such as cortical…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Yujian Xiong , Mohammad Farazi , Yanxi Chen , Wenhui Zhu , Xuanzhao Dong , Natasha Lepore , Yi Su , Raza Mushtaq , Stephen Foldes , Andrew Yang , Yalin Wang

While conventional computer vision emphasizes pixel-level and feature-based objectives, medical image analysis of intricate biological structures necessitates explicit representation of their complex topological properties. Despite their…

Image and Video Processing · Electrical Eng. & Systems 2024-12-31 Yousef Yeganeh , Rui Xiao , Goktug Guvercin , Nassir Navab , Azade Farshad

Graphical models play an important role in neuroscience studies, particularly in brain connectivity analysis. Typically, observations/samples are from several heterogenous groups and the group membership of each observation/sample is…

Methodology · Statistics 2021-10-12 Dong Liu , Changwei Zhao , Yong He , Lei Liu , Ying Guo , Xinsheng Zhang

Computer-aided diagnosis (CAD) systems play a crucial role in analyzing neuroimaging data for neurological and psychiatric disorders. However, small-sample studies suffer from low reproducibility, while large-scale datasets introduce…

Machine Learning · Computer Science 2025-08-12 Xinglin Zhao , Yanwen Wang , Xiaobo Liu , Yanrong Hao , Rui Cao , Xin Wen

Graph Transformer shows remarkable potential in brain network analysis due to its ability to model graph structures and complex node relationships. Most existing methods typically model the brain as a flat network, ignoring its modular…

Machine Learning · Computer Science 2025-11-25 Jiajun Ma , Yongchao Zhang , Chao Zhang , Zhao Lv , Shengbing Pei

We present Brain Harmony (BrainHarmonix), the first multimodal brain foundation model that unifies structural morphology and functional dynamics into compact 1D token representations. The model was pretrained on two of the largest…

Graph embedding is a powerful method to represent graph neurological data (e.g., brain connectomes) in a low dimensional space for brain connectivity mapping, prediction and classification. However, existing embedding algorithms have two…

Computer Vision and Pattern Recognition · Computer Science 2020-09-25 Alin Banka , Inis Buzi , Islem Rekik

We present PhoMoH, a neural network methodology to construct generative models of photo-realistic 3D geometry and appearance of human heads including hair, beards, an oral cavity, and clothing. In contrast to prior work, PhoMoH models the…

Computer Vision and Pattern Recognition · Computer Science 2023-10-25 Mihai Zanfir , Thiemo Alldieck , Cristian Sminchisescu

With the explosive growth of available training data, single-image 3D human modeling is ahead of a transition to a data-centric paradigm. A key to successfully exploiting data scale is to design flexible models that can be supervised from…

Computer Vision and Pattern Recognition · Computer Science 2024-12-11 István Sárándi , Gerard Pons-Moll

Graphs are quickly emerging as a leading abstraction for the representation of data. One important application domain originates from an emerging discipline called "connectomics". Connectomics studies the brain as a graph; vertices…

Pathology image segmentation across multiple centers encounters significant challenges due to diverse sources of heterogeneity including imaging modalities, organs, and scanning equipment, whose variability brings representation bias and…

Computer Vision and Pattern Recognition · Computer Science 2025-05-29 Yuan Zhang , Feng Chen , Yaolei Qi , Guanyu Yang , Huazhu Fu

At rest, human brain functional networks display striking modular architecture in which coherent clusters of brain regions are activated. The modular account of brain function is pervasive, reliable, and reproducible. Yet, a complementary…

Functional connections in the brain are frequently represented by weighted networks, with nodes representing locations in the brain, and edges representing the strength of connectivity between these locations. One challenge in analyzing…

Applications · Statistics 2022-09-28 Yura Kim , Daniel Kessler , Elizaveta Levina
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