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Understanding the structural and functional organization of the human brain requires a detailed examination of cortical folding patterns, among which the three-hinge gyrus (3HG) has been identified as a key structural landmark. GyralNet, a…

Neurons and Cognition · Quantitative Biology 2025-04-02 Yan Zhuang , Minheng Chen , Chao Cao , Tong Chen , Jing Zhang , Xiaowei Yu , Yanjun Lyu , Lu Zhang , Tianming Liu , Dajiang Zhu

The 3-hinge gyrus (3HG) is a newly defined folding pattern, which is the conjunction of gyri coming from three directions in cortical folding. Many studies demonstrated that 3HGs can be reliable nodes when constructing brain networks or…

Computer Vision and Pattern Recognition · Computer Science 2025-02-25 Minheng Chen , Chao Cao , Tong Chen , Yan Zhuang , Jing Zhang , Yanjun Lyu , Xiaowei Yu , Lu Zhang , Tianming Liu , Dajiang Zhu

Effective representation of brain anatomical architecture is fundamental in understanding brain regularity and variability. Despite numerous efforts, it is still difficult to infer reliable anatomical correspondence at finer scale, given…

Neurons and Cognition · Quantitative Biology 2022-05-30 Lu Zhang , Xiaowei Yu , Yanjun Lyu , Zhengwang Wu , Haixing Dai , Lin Zhao , Li Wang , Gang Li , Tianming Liu , Dajiang Zhu

The human cerebral cortex has many bumps and grooves called gyri and sulci. Even though there is a high inter-individual consistency for the main cortical folds, this is not the case when we examine the exact shapes and details of the…

Machine Learning · Computer Science 2024-02-01 Aymeric Gaudin , Louise Guillon , Clara Fischer , Arnaud Cachia , Denis Rivière , Jean-François Mangin , Joël Chavas

The human connectome has been widely studied over the past decade. A principal finding is that it can be decomposed into communities of densely interconnected brain regions. This result, however, may be limited methodologically. Past…

The human brain can be considered as complex networks, composed of various regions that continuously exchange their information with each other, forming the brain network graph, from which nodes and edges are extracted using resting-state…

Machine Learning · Computer Science 2025-02-19 Parnian Jalali , Mehran Safayani

Brain connectomics is still largely dominated by pairwise-based models, such as graphs, which cannot represent circulatory or higher-order functional interactions. In this paper, we propose a multimodal framework based on Topological Signal…

Neurons and Cognition · Quantitative Biology 2026-04-01 Breno C. Bispo , Stefania Sardellitti , Juliano B. Lima , Fernando A. N. Santos

Understanding the cortical organization of the human brain requires interpretable descriptors for distinct structural and functional imaging data. 3D polarized light imaging (3D-PLI) is an imaging modality for visualizing fiber architecture…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Alexander Oberstrass , Jordan DeKraker , Nicola Palomero-Gallagher , Sascha E. A. Muenzing , Alan C. Evans , Markus Axer , Katrin Amunts , Timo Dickscheid

Integrating structural and functional connectomes remains challenging because their relationship is non-linear and organized over nested modular hierarchies. We propose a hierarchical multiscale structure-function coupling framework for…

Structural connectivity in the brain is typically studied by reducing its observation to a single spatial resolution. However, the brain possesses a rich architecture organized over multiple scales linked to one another. We explored the…

Physics and Society · Physics 2020-09-07 Muhua Zheng , Antoine Allard , Patric Hagmann , Yasser Alemán-Gómez , M. Ángeles Serrano

Alzheimer's disease (AD) and Lewy body dementia (LBD) present overlapping clinical features yet require distinct diagnostic strategies. While neuroimaging-based brain network analysis is promising, atlas-based representations may obscure…

Neurons and Cognition · Quantitative Biology 2026-02-25 Minheng Chen , Tong Chen , Chao Cao , Jing Zhang , Tianming Liu , Li Su , Dajiang Zhu

Our brain functions as a complex communication network, and studying it from a network perspective offers valuable insights into its organizational principles and links to cognitive functions and brain disorders. However, most current…

Neurons and Cognition · Quantitative Biology 2026-01-21 Chao Cao , Tong Chen , Nan Zhao , Minheng Chen , Michael Qu , Zeyu Zhang , Xiao Shi , Xiang Li , Tianming Liu , Lu Zhang

Since gyri and sulci, two basic anatomical building blocks of cortical folding patterns, were suggested to bear different functional roles, a precise mapping from brain function to gyro-sulcal patterns can provide profound insights into…

Neurons and Cognition · Quantitative Biology 2022-05-24 Li Yang , Zhibin He , Changhe Li , Junwei Han , Dajiang Zhu , Tianming Liu , Tuo Zhang

Community detection algorithms have been widely used to study the organization of complex systems like the brain. A principal appeal of these techniques is their ability to identify a partition of brain regions (or nodes) into communities,…

Neurons and Cognition · Quantitative Biology 2017-04-20 Arian Ashourvan , Qawi K. Telesford , Timothy Verstynen , Jean M. Vettel , Danielle S. Bassett

Individual differences in human intelligence can be modeled and predicted from in vivo neurobiological connectivity. Many established modeling frameworks for predicting intelligence, however, discard higher-order information about…

Neurons and Cognition · Quantitative Biology 2022-03-07 Evan D. Anderson , Ramsey Wilcox , Anuj Nayak , Christopher Zwilling , Pablo Robles-Granda , Been Kim , Lav R. Varshney , Aron K. Barbey

Representation learning has been essential for graph machine learning tasks such as link prediction, community detection, and network visualization. Despite recent advances in achieving high performance on these downstream tasks, little…

Machine Learning · Computer Science 2026-02-26 Nikolaos Nakis , Chrysoula Kosma , Panagiotis Promponas , Michail Chatzianastasis , Giannis Nikolentzos

Quantification of brain morphology has become an important cornerstone in understanding brain structure. Measures of cortical morphology such as thickness and surface area are frequently used to compare groups of subjects or characterise…

Neurons and Cognition · Quantitative Biology 2020-03-25 Yujiang Wang , Tobias Ludwig , Bethany Little , Joe H Necus , Gavin Winston , Sjoerd B Vos , Jane de Tisi , John S Duncan , Peter N Taylor , Bruno Mota

Human brain structural networks contain sets of centrally embedded hub regions that enable efficient information communication. However, it remains largely unknown about categories of structural brain hubs and their microstructural,…

Neurons and Cognition · Quantitative Biology 2016-09-13 Xindi Wang , Qixiang Lin , Mingrui Xia , Yong He

The use of EEG biometrics, for the purpose of automatic people recognition, has received increasing attention in the recent years. Most of current analysis rely on the extraction of features characterizing the activity of single brain…

Neurons and Cognition · Quantitative Biology 2014-09-10 Daria La Rocca , Patrizio Campisi , Balazs Vegso , Peter Cserti , Gyorgy Kozmann , Fabio Babiloni , Fabrizio De Vico Fallani

Human brain anatomy and function display a combination of modular and hierarchical organization, suggesting the importance of both cohesive structures and variable resolutions in the facilitation of healthy cognitive processes. However,…

Neurons and Cognition · Quantitative Biology 2015-06-18 Christian Lohse , Danielle S. Bassett , Kelvin O. Lim , Jean M. Carlson
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