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The emergence of label-free microscopy techniques has significantly improved our ability to precisely characterize biochemical targets, enabling non-invasive visualization of cellular organelles and tissue organization. Each label-free…

Optics · Physics 2024-05-08 Lang Wang , Maxine Xii , Ali Pezeshki , Randy Bartels

Scanning Transmission Electron Microscopy (STEM) has become the main stay for materials characterization on atomic level, with applications ranging from visualization of localized and extended defects to mapping order parameter fields. In…

Instrumentation and Detectors · Physics 2019-01-15 Xin Li , Ondrej Dyck , Sergei V. Kalinin , Stephen Jesse

Squeezing of light's quantum noise requires temporal rearranging of photons. This again corresponds to creation of quantum correlations between individual photons. Squeezed light is a non-classical manifestation of light with great…

Microscopic imaging of local magnetic fields provides a window into the organizing principles of complex and technologically relevant condensed matter materials. However, a wide variety of intriguing strongly correlated and topologically…

Mesoscale and Nanoscale Physics · Physics 2017-04-05 Fan Yang , Alicia J. Kollár , Stephen F. Taylor , Richard W. Turner , Benjamin L. Lev

Sensors that are able to detect and track single unlabelled biomolecules are an important tool both to understand biomolecular dynamics and interactions at nanoscale, and for medical diagnostics operating at their ultimate detection limits.…

Optics · Physics 2016-11-15 N. P. Mauranyapin , L. S. Madsen , M. A. Taylor , M. Waleed , W. P. Bowen

Purpose: Spectral imaging is a method in medical x-ray imaging to extract information about the object constituents by the material-specific energy dependence of x-ray attenuation. The authors have investigated a photon-counting spectral…

Medical Physics · Physics 2021-01-21 Erik Fredenberg , Magnus Hemmendorff , Bjorn Cederstrom , Magnus Aslund , Mats Danielsson

Downsampling images and labels, often necessitated by limited resources or to expedite network training, leads to the loss of small objects and thin boundaries. This undermines the segmentation network's capacity to interpret images…

Image and Video Processing · Electrical Eng. & Systems 2024-10-27 Shahzad Ali , Yu Rim Lee , Soo Young Park , Won Young Tak , Soon Ki Jung

The dynamics of photo-excited charge carriers, particularly their transport and interactions with defects and interfaces, play an essential role in determining the performance of a wide range of solar and optoelectronic devices. A thorough…

Materials Science · Physics 2017-08-07 Bolin Liao , Ebrahim Najafi

Label-free optical imaging is valuable in biology and medicine with its non-destructive property and reduced optical and chemical damages. Quantitative phase (QPI) and molecular vibrational imaging (MVI) are the two most successful…

According to quantum theory the interactions between physical systems are quantized. As a direct consequence, measurement sensitivities are fundamentally limited by quantization noise, or just `quantum noise' in short. Furthermore,…

Quantum Physics · Physics 2017-12-19 Roman Schnabel

Intermediate band solar cells (IBSCs) pursue the increase in efficiency by absorbing below-bandgap energy photons while preserving the output voltage. Experimental IBSCs based on quantum dots have already demonstrated that both…

Mesoscale and Nanoscale Physics · Physics 2021-01-14 Juan Villa , Iñigo Ramiro , José María Ripalda , Ignacio Tobías , Pablo García-Linares , Elisa Antolín , Antonio Martí

We investigate the prospects of using two-mode intensity squeezed twin-beams, generated in Rb vapor, to improve the sensitivity of spectroscopic measurements by engaging two-photon Raman transitions. As a proof of principle demonstration,…

Atomic Physics · Physics 2021-04-21 Nikunjkumar Prajapati , Ziqi Niu , Irina Novikova

Thermal transport in nanostructures plays a critical role in modern technologies. As devices shrink, techniques that can measure thermal properties at nanometer and nanosecond scales are increasingly needed to capture transient,…

Conditional Measurement scheme which employs linear optical elements and photon detection is the fertile ground for nonclassical state generation. We consider a simple setup that requires a coherent state and a number state as inputs of the…

Quantum Physics · Physics 2024-12-30 Devibala Esakkimuthu , Basherrudin Mahmud Ahmed A

We demonstrate a sub-shot-noise-limit discrimination of on-off keyed coherent signals by an optimal displacement quantum receiver in which a superconducting transition edge sensor is installed. Use of a transition edge sensor and a fiber…

An innovative and novel quartz-enhanced photoacoustic spectroscopy (QEPAS) sensor for highly sensitive and selective breath gas analysis is introduced. The QEPAS sensor consists of two acoustically coupled micro-resonators (mR) with an…

Instrumentation and Detectors · Physics 2017-04-28 Jan C. Petersen , Laurent Lamard , Yuyang Feng , J-F. Focant , Andre peremans , Mikael Lassen

Quantum materials exhibit phases such as superconductivity at low temperatures, yet imaging their phase transition dynamics with high spatial resolution remains challenging due to conventional tools' limitations - scanning tunneling…

Mesoscale and Nanoscale Physics · Physics 2025-03-04 Chen Wang , Shaoshan Wang , Chuan Guo , Chengjian Yu , Qi Fu , Xiaopeng Xie , Changxi Zheng

Spectroscopy is an important tool for probing the properties of materials, chemicals and biological samples. We design a practical transmitter-receiver system that exploits entanglement to achieve a provable quantum advantage over all…

Quantum Physics · Physics 2020-11-03 Haowei Shi , Zheshen Zhang , Stefano Pirandola , Quntao Zhuang

Recently, the self-supervised pre-training paradigm has shown great potential in leveraging large-scale unlabeled data to improve downstream task performance. However, increasing the scale of unlabeled pre-training data in real-world…

Computer Vision and Pattern Recognition · Computer Science 2022-12-13 Yiqi Lin , Huabin Zheng , Huaping Zhong , Jinjing Zhu , Weijia Li , Conghui He , Lin Wang

Optical microscopy has a diffraction limited resolution of about 250 nm. Fluorescence methods (e.g. PALM, STORM, STED) beat this, but they are still limited to 10 s of nm, and the images are an indirect pointillist representation of only…