Related papers: Quantum Squeezing Enhanced Photothermal Microscopy
Quantum imaging is emerging as a transformative approach for biomedical applications, applying nonclassical properties of light, such as entanglement, squeezing, and quantum correlations, to overcome fundamental limits of conventional…
We study the use of squeezed probe light and evasion of measurement back-action to enhance the sensitivity and measurement bandwidth of an optically-pumped magnetometer (OPM) at sensitivity-optimal atom number density. By experimental…
Positron Emission Tomography (PET) is a widely-used imaging modality for medical research and clinical diagnosis. Here we demonstrate, through detailed experiments and simulations, an exploration of the benefits of exploiting the quantum…
Mid-infrared photothermal microscopy is a new chemical imaging technology in which a visible beam senses the photothermal effect induced by a pulsed infrared laser. This technology provides infrared spectroscopic information at sub-micron…
Image sensors are the backbone of many imaging technologies of great importance to modern sciences, being particularly relevant in biomedicine. An ideal image sensor should be usable through all the electromagnetic spectrum (large…
The transmission electron microscope facilitates the highest-resolution imaging of any instrument ever created, and its limiting factor is no longer spatial resolution but dose efficiency. Low electron doses avoid sample damage but produce…
Recent years have seen the development of quantum sensing concepts utilizing nonlinear interferometers based on correlated photon pairs generated by spontaneous parametric down-conversion (SPDC). Using SPDC far from frequency degeneracy…
We study quantum enhancement of sensitivity using squeezed light in a multi-parameter quantum sensor, the hybrid dc-rf optically pumped magnetometer (hOPM) [Phys. Rev. Applied 21, 034054, (2024)]. Using a single spin ensemble, the hOPM…
In this study, we introduce a Compton SPECT system for whole-body imaging of Actinium-225 (225Ac), one of the trending radionuclides for targeted alpha therapy (TAT). The Compton SPECT system enables multi-energy gamma photon detection with…
Absorption imaging is a commonly adopted method to acquire, with high temporal resolution, spatial information on a partially transparent object. It relies on the interference between a probe beam and the coherent response of the object. In…
Interferometric scattering (iSCAT) microscopy is a powerful tool for label-free sensitive detection and imaging of nanoparticles to high spatio-temporal resolution. As it was born out of detection principles central to conventional…
Resistive Pulse Sensing (RPS) is a key label-free technology to measure particles and single-cell size distribution. As a growing corpus of evidence supports that cancer cells exhibit distinct mechanical phenotypes from healthy cells,…
Quantum state tomography (QST) is a crucial tool for characterizing quantum states. However, QST becomes impractical for reconstructing multi-qubit density matrices since data sets and computational costs grow exponentially with qubit…
Strongly squeezed light finds many important applications within the fields of quantum metrology, quantum communication and quantum computation. However, due to the bulkiness and complexity of most squeezed light sources of today, they are…
As part of the effort to make use of squeezed states of light for detection of sub-shot-noise optical signals, we study the balanced heterodyne scheme, for which the corresponding spectral density of the photocurrent fluctuations produced…
Optical frequency combs, named for their comb-like peaks in the spectrum, are essential for various sensing applications. As the technology develops, its performance has reached the standard quantum limit dictated by the quantum…
An improved method of remote optical absorption spectroscopy and hyperspectral optical absorption imaging is described which takes advantage of the photoacoustic remote sensing detection architecture. A wide range of photoacoustic…
Intracellular chromophores (e.g., NADH and FAD) play a central role in regulation of cellular metabolism. Though autofluorescence has been extensively used for label-free mapping of chromophores inside a cell, its sensitivity and molecular…
A crucial limitation of current high-resolution 3D photoacoustic tomography (PAT) devices that employ sequential scanning is their long acquisition time. In previous work, we demonstrated how to use compressed sensing techniques to improve…
Squeezed light is a key quantum resource that enables quantum advantages for sensing, networking, and computing applications. The scalable generation and manipulation of squeezed light with integrated platforms are highly desired for the…