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We study coherent quantum control strategy which is robust with respect to coupling with an external environment. We model this interaction by appending an additional subsystem to the initial system and we choose the strength of the…

Quantum Physics · Physics 2017-08-02 Łukasz Pawela , Zbigniew Puchała

Autonomous systems have witnessed a rapid increase in their capabilities, but it remains a challenge for them to perform tasks both effectively and safely. The fact that performance and safety can sometimes be competing objectives renders…

Systems and Control · Electrical Eng. & Systems 2024-12-04 Hao Wang , Adityaya Dhande , Somil Bansal

We address a wide spectrum of quantum control strategies, including various open-loop protocols and advanced adaptive methods. These methodologies apply to few-qubit scenarios and naturally scale to larger N-qubit systems. We benchmark them…

Quantum Physics · Physics 2025-09-22 Atta ur Rahman , M. Y. Abd-Rabbou , Cong-feng Qiao

In recent years, quantum, quantum-inspired, and hybrid algorithms are increasingly showing promise for solving software engineering optimization problems. However, best-intended practices for conducting empirical studies have not yet well…

Software Engineering · Computer Science 2025-11-03 Man Zhang , Yuechen Li , Tao Yue , Kai-Yuan Cai

Achieving superpolynomial speedups for optimization has long been a central goal for quantum algorithms. Here we introduce Decoded Quantum Interferometry (DQI), a quantum algorithm that uses the quantum Fourier transform to reduce…

In this paper, a methodology is proposed that enables to analyze the sensitivity of the outcome of a therapy to unavoidable high dispersion of the patient specific parameters on one hand and to the choice of the parameters that define the…

Systems and Control · Electrical Eng. & Systems 2022-05-17 Mazen Alamir

Predicting drug-target interaction (DTI) is critical in the drug discovery process. Despite remarkable advances in recent DTI models through the integration of representations from diverse drug and target encoders, such models often…

Quantitative Methods · Quantitative Biology 2025-09-30 Zhaohan Meng , Zaiqiao Meng , Ke Yuan , Iadh Ounis

Quantum optimal control includes the family of pulse-shaping algorithms that aim to unlock the full potential of a variety of quantum technologies. Our Quantum Optimal Control Suite (QuOCS) unites experimental focus and model-based…

Optimally-shaped electromagnetic fields have the capacity to coherently control the dynamics of quantum systems and thus offer a promising means for controlling molecular transformations relevant to chemical, biological, and materials…

Quantum Physics · Physics 2021-06-08 Alicia B. Magann , Matthew D. Grace , Herschel A. Rabitz , Mohan Sarovar

To enhance the robustness of cooperative driving to cyberattacks, we study a controller-oriented approach to mitigate the effect of a class of False-Data Injection (FDI) attacks. By reformulating a given dynamic Cooperative Adaptive Cruise…

Systems and Control · Electrical Eng. & Systems 2024-10-29 Mischa Huisman , Carlos Murguia , Erjen Lefeber , Nathan van de Wouw

Drug discovery is lengthy and expensive, with traditional computer-aided design facing limits. This paper examines integrating quantum computing across the drug development cycle to accelerate and enhance workflows and rigorous…

We introduce a quantum algorithm integrating counterdiabatic (CD) protocols with quantum Lyapunov control (QLC) to tackle combinatorial optimization problems. This approach offers versatility, allowing implementation as either a…

Quantum Physics · Physics 2024-09-20 Pranav Chandarana , Koushik Paul , Kasturi Ranjan Swain , Xi Chen , Adolfo del Campo

A central challenge in quantum information science and technology is achieving real-time estimation and feedforward control of quantum systems. This challenge is compounded by the inherent inhomogeneity of quantum resources, such as qubit…

Machine Learning · Computer Science 2024-05-28 Linsen Li , Pratyush Anand , Kaiming He , Dirk Englund

Hybrid quantum-classical machine learning offers a path to leverage noisy intermediate-scale quantum (NISQ) devices for drug discovery, but optimal model architectures remain unclear. We systematically optimize the quantum-classical bridge…

Machine Learning · Computer Science 2025-07-28 Andrew Smith , Erhan Guven

Distributed control algorithms are known to reduce overall computation time compared to centralized control algorithms. However, they can result in inconsistent solutions leading to the violation of safety-critical constraints. Inconsistent…

Systems and Control · Electrical Eng. & Systems 2024-11-26 Julius Beerwerth , Maximilian Kloock , Bassam Alrifaee

Recently, there has been a surge of research on a class of methods called feedback optimization. These are methods to steer the state of a control system to an equilibrium that arises as the solution of an optimization problem. Despite the…

Optimization and Control · Mathematics 2026-02-18 Giannis Delimpaltadakis , Pol Mestres , Jorge Cortés , W. P. M. H. Heemels

Drug-drug interaction event (DDIE) prediction is crucial for preventing adverse reactions and ensuring optimal therapeutic outcomes. However, existing methods often face challenges with imbalanced datasets, complex interaction mechanisms,…

Machine Learning · Computer Science 2026-03-16 Pengfei Liu , Jun Tao , Zhixiang Ren

The convergence of policy gradient algorithms hinges on the optimization landscape of the underlying optimal control problem. Theoretical insights into these algorithms can often be acquired from analyzing those of linear quadratic control.…

Optimization and Control · Mathematics 2023-11-02 Jingliang Duan , Wenhan Cao , Yang Zheng , Lin Zhao

Motivation: Emerging drug-drug interaction (DDI) prediction is crucial for new drugs but is hindered by distribution changes between known and new drugs in real-world scenarios. Current evaluation often neglects these changes, relying on…

Machine Learning · Computer Science 2025-10-17 Zhenqian Shen , Mingyang Zhou , Yongqi Zhang , Quanming Yao

Dynamical decoupling (DD) is a promising technique for mitigating errors in near-term quantum devices. However, its effectiveness depends on both hardware characteristics and algorithm implementation details. This paper explores the…

Quantum Physics · Physics 2024-08-20 Yanjun Ji , Ilia Polian