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Spatial transcriptomics enables interrogating the molecular composition of tissue with ever-increasing resolution and sensitivity. However, costs, rapidly evolving technology, and lack of standards have constrained computational methods in…

Genome sequence analysis has enabled significant advancements in medical and scientific areas such as personalized medicine, outbreak tracing, and the understanding of evolution. Unfortunately, it is currently bottlenecked by the…

In this work, we propose using a unified representation, termed Factorized Features, for low-level vision tasks, where we test on Single Image Super-Resolution (SISR) and \textbf{Image Compression}. Motivated by the shared principles…

Image and Video Processing · Electrical Eng. & Systems 2025-11-04 Yang-Che Sun , Cheng Yu Yeo , Ernie Chu , Jun-Cheng Chen , Yu-Lun Liu

Next generation sequencing technology rapidly produces massive volume of data and quality control of this sequencing data is essential to any genomic analysis. Here we present MEEPTOOLS, which is a collection of open-source tools based on…

Genomics · Quantitative Biology 2015-12-11 Vishal N. Koparde , Hardik I. Parikh , Steven P. Bradley , Nihar U. Sheth

Transformer-based methods have exhibited remarkable potential in single image super-resolution (SISR) by effectively extracting long-range dependencies. However, most of the current research in this area has prioritized the design of…

Computer Vision and Pattern Recognition · Computer Science 2024-12-04 Ao Li , Le Zhang , Yun Liu , Ce Zhu

Clustering is an essential data mining tool for analyzing and grouping similar objects. In big data applications, however, many clustering algorithms are infeasible due to their high memory requirements and/or unfavorable runtime…

Data Structures and Algorithms · Computer Science 2026-01-27 Gregor Ulm , Simon Smith , Adrian Nilsson , Emil Gustavsson , Mats Jirstrand

Ternary Neural Networks (TNNs) have received much attention due to being potentially orders of magnitude faster in inference, as well as more power efficient, than full-precision counterparts. However, 2 bits are required to encode the…

Machine Learning · Computer Science 2021-07-30 Peng Chen , Bohan Zhuang , Chunhua Shen

Prokaryotic organisms usually possess compact genomes, which are particularly suitable to complete sequencing with existing technologies, which led to an escalating accumulation of available genome data. In response to this ever-expanding…

Genomics · Quantitative Biology 2024-03-05 Giorgio Gonnella

Four-dimensional scanning transmission electron microscopy (4D-STEM) generates multi-gigabyte datasets, creating a growing mismatch between acquisition rates and practical storage, transfer, and interactive visualization capabilities. We…

Signal Processing · Electrical Eng. & Systems 2026-04-09 Ondrej Dyck , Andrew R. Lupini , Albina Borisevich , Miaofang Chi , Rama K. Vasudevan , Stephen Jesse

FastText has established itself as a fundamental algorithm for learning word representations, demonstrating exceptional capability in handling out-of-vocabulary words through character-level n-gram embeddings. However, its hash-based…

Computation and Language · Computer Science 2025-06-03 Yimin Du

Traditional lossless text compression preserves every byte, but its gains on natural language are often modest in realistic operating regimes. We study \emph{lossy semantic text compression}, where the encoder strategically deletes parts of…

Computation and Language · Computer Science 2026-05-29 Yuchun Zou , Junhong Tong , Jun Li

Fully Homomorphic Encryption (FHE) is a set of powerful cryptographic schemes that allows computation to be performed directly on encrypted data with an unlimited depth. Despite FHE's promising in privacy-preserving computing, yet in most…

Cryptography and Security · Computer Science 2025-04-23 Yi Huang , Xinsheng Gong , Xiangyu Kong , Dibei Chen , Jianfeng Zhu , Wenping Zhu , Liangwei Li , Mingyu Gao , Shaojun Wei , Aoyang Zhang , Leibo Liu

Spatial transcriptomics provides an unprecedented perspective for deciphering tissue spatial heterogeneity. However, high-resolution spatial transcriptomic technology remains constrained by limited gene coverage, technical complexity, and…

Biomolecules · Quantitative Biology 2026-05-19 Xinlei Huang , Weihao Dai , Zijun Qin , Xin Yu , Di Wang , Yanran Liu , Lixin Cheng , Xubin Zheng

The ability to learn new concepts continually is necessary in this ever-changing world. However, deep neural networks suffer from catastrophic forgetting when learning new categories. Many works have been proposed to alleviate this…

Computer Vision and Pattern Recognition · Computer Science 2022-07-21 Fu-Yun Wang , Da-Wei Zhou , Han-Jia Ye , De-Chuan Zhan

Recurrent Neural Networks (RNNs) have been widely used in sequence analysis and modeling. However, when processing high-dimensional data, RNNs typically require very large model sizes, thereby bringing a series of deployment challenges.…

Computer Vision and Pattern Recognition · Computer Science 2021-04-21 Miao Yin , Siyu Liao , Xiao-Yang Liu , Xiaodong Wang , Bo Yuan

Because tensor data appear more and more frequently in various scientific researches and real-world applications, analyzing the relationship between tensor features and the univariate outcome becomes an elementary task in many fields. To…

Machine Learning · Computer Science 2019-12-04 Jiaqi Zhang , Beilun Wang

Although there have been significant advancements in image compression techniques, such as standard and learned codecs, these methods still suffer from severe quality degradation at extremely low bits per pixel. While recent diffusion-based…

Image and Video Processing · Electrical Eng. & Systems 2025-09-23 Chanung Park , Joo Chan Lee , Jong Hwan Ko

Deep-learning-based compressor has received interests recently due to much improved compression ratio. However, modern approaches suffer from long execution time. To ease this problem, this paper targets on cutting down the execution time…

Machine Learning · Computer Science 2022-04-04 Yu Mao , Yufei Cui , Tei-Wei Kuo , Chun Jason Xue

Efficiently encoding classical visual data into quantum states is essential for realizing practical quantum neural networks (QNNs). However, existing encoding schemes often discard spatial and semantic information when adapting…

Quantum Physics · Physics 2025-11-20 Yuhu Lu , Jinjing Shi

Model quantization is a widely used technique to compress and accelerate deep neural network (DNN) inference. Emergent DNN hardware accelerators begin to support mixed precision (1-8 bits) to further improve the computation efficiency,…

Computer Vision and Pattern Recognition · Computer Science 2019-04-09 Kuan Wang , Zhijian Liu , Yujun Lin , Ji Lin , Song Han