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The Science of Science (SoS) explores the mechanisms underlying scientific discovery, and offers valuable insights for enhancing scientific efficiency and fostering innovation. Traditional approaches often rely on simplistic assumptions and…

Artificial Intelligence · Computer Science 2025-05-20 Renqi Chen , Haoyang Su , Shixiang Tang , Zhenfei Yin , Qi Wu , Hui Li , Ye Sun , Nanqing Dong , Wanli Ouyang , Philip Torr

The paper surveys automated scientific discovery, from equation discovery and symbolic regression to autonomous discovery systems and agents. It discusses the individual approaches from a "big picture" perspective and in context, but also…

Artificial Intelligence · Computer Science 2026-05-01 Stefan Kramer , Mattia Cerrato , Jannis Brugger , Sašo Džeroski , Ross King

Fully autonomous teams of LLM-powered AI agents are emerging that collaborate to perform complex tasks for users. What challenges do developers face when trying to build and debug these AI agent teams? In formative interviews with five AI…

Multiagent Systems · Computer Science 2025-03-06 Will Epperson , Gagan Bansal , Victor Dibia , Adam Fourney , Jack Gerrits , Erkang Zhu , Saleema Amershi

In the rapidly advancing research fields such as AI, managing and staying abreast of the latest scientific literature has become a significant challenge for researchers. Although previous efforts have leveraged AI to assist with literature…

Computation and Language · Computer Science 2024-04-10 Xintao Wang , Jiangjie Chen , Nianqi Li , Lida Chen , Xinfeng Yuan , Wei Shi , Xuyang Ge , Rui Xu , Yanghua Xiao

The potential of AI researchers in scientific discovery remains largely untapped. Over the past decade, AI for Science (AI4Science) publications in 145 Nature Index journals have increased fifteen-fold, yet they still account for less than…

Computers and Society · Computer Science 2025-09-24 Hengjie Yu , Shuya Liu , Haiyun Yang , Yuping Yan , Maozhen Qu , Yaochu Jin

AI-powered scientific research tools are rapidly being integrated into research workflows, yet the field lacks a clear lens into how researchers use these systems in real-world settings. We present and analyze the Asta Interaction Dataset,…

With recent advancements in multi-agent generative AI (Gen AI), technology organizations like Microsoft are adopting these complex tools, redefining AI agents as active collaborators in complex workflows rather than as passive tools. In…

Human-Computer Interaction · Computer Science 2025-10-09 Suchismita Naik , Austin L. Toombs , Amanda Snellinger , Scott Saponas , Amanda K. Hall

Information retrieval is a cornerstone of modern knowledge acquisition, enabling billions of queries each day across diverse domains. However, traditional keyword-based search engines are increasingly inadequate for handling complex,…

Artificial intelligence (AI) is reshaping education, scientific training, and materials discovery. In materials science, AI models increasingly support property prediction, experiment prioritization, and hypothesis generation; however, the…

Physics Education · Physics 2026-05-12 Dongming Mei , Katherine Moore , Ben Sayler

As many of us in the information retrieval (IR) research community know and appreciate, search is far from being a solved problem. Millions of people struggle with tasks on search engines every day. Often, their struggles relate to the…

Information Retrieval · Computer Science 2024-04-04 Ryen W. White

We introduce the STATION, an open-world multi-agent environment for autonomous scientific discovery. The Station simulates a complete scientific ecosystem, where agents can engage in long scientific journeys that include reading papers from…

Artificial Intelligence · Computer Science 2025-12-02 Stephen Chung , Wenyu Du

In the upcoming decade, deep learning may revolutionize the natural sciences, enhancing our capacity to model and predict natural occurrences. This could herald a new era of scientific exploration, bringing significant advancements across…

Artificial Intelligence · Computer Science 2023-10-13 Shuaiwen Leon Song , Bonnie Kruft , Minjia Zhang , Conglong Li , Shiyang Chen , Chengming Zhang , Masahiro Tanaka , Xiaoxia Wu , Jeff Rasley , Ammar Ahmad Awan , Connor Holmes , Martin Cai , Adam Ghanem , Zhongzhu Zhou , Yuxiong He , Pete Luferenko , Divya Kumar , Jonathan Weyn , Ruixiong Zhang , Sylwester Klocek , Volodymyr Vragov , Mohammed AlQuraishi , Gustaf Ahdritz , Christina Floristean , Cristina Negri , Rao Kotamarthi , Venkatram Vishwanath , Arvind Ramanathan , Sam Foreman , Kyle Hippe , Troy Arcomano , Romit Maulik , Maxim Zvyagin , Alexander Brace , Bin Zhang , Cindy Orozco Bohorquez , Austin Clyde , Bharat Kale , Danilo Perez-Rivera , Heng Ma , Carla M. Mann , Michael Irvin , J. Gregory Pauloski , Logan Ward , Valerie Hayot , Murali Emani , Zhen Xie , Diangen Lin , Maulik Shukla , Ian Foster , James J. Davis , Michael E. Papka , Thomas Brettin , Prasanna Balaprakash , Gina Tourassi , John Gounley , Heidi Hanson , Thomas E Potok , Massimiliano Lupo Pasini , Kate Evans , Dan Lu , Dalton Lunga , Junqi Yin , Sajal Dash , Feiyi Wang , Mallikarjun Shankar , Isaac Lyngaas , Xiao Wang , Guojing Cong , Pei Zhang , Ming Fan , Siyan Liu , Adolfy Hoisie , Shinjae Yoo , Yihui Ren , William Tang , Kyle Felker , Alexey Svyatkovskiy , Hang Liu , Ashwin Aji , Angela Dalton , Michael Schulte , Karl Schulz , Yuntian Deng , Weili Nie , Josh Romero , Christian Dallago , Arash Vahdat , Chaowei Xiao , Thomas Gibbs , Anima Anandkumar , Rick Stevens

We present \textsc{WisPaper}, an end-to-end agent system that transforms how researchers discover, organize, and track academic literature. The system addresses two fundamental challenges. (1)~\textit{Semantic search limitations}: existing…

Meta-analyses and systematic reviews demand rigorous abductive reasoning to build, test, and refine hypotheses across vast, heterogeneous literature. While NLP advancements have automated parts of this pipeline, existing tools often detach…

Human-Computer Interaction · Computer Science 2026-01-27 Sizhe Cheng , Feng Liang , Yuhan Wen , Xipei Yu , Yong Wang

Recent advances in large language models (LLMs) have enabled the development of AI agents that exhibit increasingly human-like behaviors, including planning, adaptation, and social dynamics across diverse, interactive, and open-ended…

Neurons and Cognition · Quantitative Biology 2025-06-13 Lin Chen , Yunke Zhang , Jie Feng , Haoye Chai , Honglin Zhang , Bingbing Fan , Yibo Ma , Shiyuan Zhang , Nian Li , Tianhui Liu , Nicholas Sukiennik , Keyu Zhao , Yu Li , Ziyi Liu , Fengli Xu , Yong Li

Many challenges remain before AI agents can be deployed in real-world environments. However, one virtue of such environments is that they are inherently multi-agent and contain human experts. Using advanced social intelligence in such an…

Machine Learning · Computer Science 2025-08-22 Eric Ye , Ren Tao , Natasha Jaques

We introduce DeepResearch$^{\text{Eco}}$, a novel agentic LLM-based system for automated scientific synthesis that supports recursive, depth- and breadth-controlled exploration of original research questions -- enhancing search diversity…

Artificial Intelligence · Computer Science 2025-07-15 Jennifer D'Souza , Endres Keno Sander , Andrei Aioanei

Designing a generalist scientific agent capable of performing tasks in laboratory settings to assist researchers has become a key goal in recent Artificial Intelligence (AI) research. Unlike everyday tasks, scientific tasks are inherently…

Computation and Language · Computer Science 2026-03-20 Minh Pham Dinh , Munira Syed , Michael G Yankoski , Trenton W. Ford

We report a framework that enables the wide adoption of authentic research educational methodology at various schools by addressing common barriers. The guiding principles we present were applied to implement a program in which teams of…

Computers and Society · Computer Science 2024-07-09 Sergey V Samsonau , Aziza Kurbonova , Lu Jiang , Hazem Lashen , Jiamu Bai , Theresa Merchant , Ruoxi Wang , Laiba Mehnaz , Zecheng Wang , Ishita Patil

Generative AI (GenAI) tools are radically expanding the scope and capability of automation in knowledge work such as academic research. While promising for augmenting cognition and streamlining processes, AI-assisted research tools may also…

Human-Computer Interaction · Computer Science 2025-04-22 Runlong Ye , Matthew Varona , Oliver Huang , Patrick Yung Kang Lee , Michael Liut , Carolina Nobre