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Current Autonomous Scientific Research (ASR) systems, despite leveraging large language models (LLMs) and agentic architectures, remain constrained by fixed workflows and toolsets that prevent adaptation to evolving tasks and environments.…

Artificial Intelligence · Computer Science 2026-04-01 Martin Legrand , Tao Jiang , Matthieu Feraud , Benjamin Navet , Yousouf Taghzouti , Fabien Gandon , Elise Dumont , Louis-Félix Nothias

Modern scientific research relies on large-scale data, complex workflows, and specialized tools, which existing LLMs and tool-based agents struggle to handle due to limitations in long-horizon planning, robust goal maintenance, and…

Artificial Intelligence · Computer Science 2026-02-11 NexusAgent Team

Large language model (LLM)-based systems are increasingly deployed to conduct scientific research autonomously, yet whether their reasoning adheres to the epistemic norms that make scientific inquiry self-correcting is poorly understood.…

The performance gap between closed-source and open-source large language models (LLMs) is largely attributed to disparities in access to high-quality training data. To bridge this gap, we introduce a novel framework for the automated…

Agentic AI systems are increasingly capable of performing professional and personal tasks with limited human involvement. However, tracking these developments is difficult because the AI agent ecosystem is complex, rapidly evolving, and…

Computers and Society · Computer Science 2026-05-07 Leon Staufer , Kevin Feng , Kevin Wei , Luke Bailey , Yawen Duan , Mick Yang , A. Pinar Ozisik , Stephen Casper , Noam Kolt

AI research agents are demonstrating great potential to accelerate scientific progress by automating the design, implementation, and training of machine learning models. We focus on methods for improving agents' performance on MLE-bench, a…

Large language models are moving scientific research from text assistance toward agentic workflows, yet biological research requires strong object validation, methodological suitability, reproducibility, and auditability. Prompt…

Quantitative Methods · Quantitative Biology 2026-05-25 Zhenyu Ma , Yuyang Song , Chunyi Yang , Jingyi Zhu , Limei Xu , Min Xiao , Xukai Jiang

AI agents are beginning to interact with each other directly and across internet platforms and physical environments, creating security challenges beyond traditional cybersecurity and AI safety frameworks. Free-form protocols are essential…

Open-source scientific software is abundant, yet most tools remain difficult to compile, configure, and reuse, sustaining a small-workshop mode of scientific computing. This deployment bottleneck limits reproducibility, large-scale…

Software Engineering · Computer Science 2026-01-08 Yi Wang , Zhenting Huang , Zhaohan Ding , Ruoxue Liao , Yuan Huang , Xinzijian Liu , Jiajun Xie , Siheng Chen , Linfeng Zhang

AI-powered web agents have the potential to automate repetitive tasks, such as form filling, information retrieval, and scheduling, but they struggle to reliably execute these tasks without human intervention, requiring users to provide…

Human-Computer Interaction · Computer Science 2026-01-27 Yimeng Liu , Misha Sra , Jeevana Priya Inala , Chenglong Wang

AI agents have the potential to aid users on a variety of consequential tasks, including conducting scientific research. To spur the development of useful agents, we need benchmarks that are challenging, but more crucially, directly…

Computation and Language · Computer Science 2024-09-18 Zachary S. Siegel , Sayash Kapoor , Nitya Nagdir , Benedikt Stroebl , Arvind Narayanan

Artificial Intelligence (AI) agents capable of autonomous learning and independent decision-making hold great promise for addressing complex challenges across various critical infrastructure domains, including transportation, energy…

Multiagent Systems · Computer Science 2025-07-02 Hepeng Li , Yuhong Liu , Jun Yan , Jie Gao , Xiaoou Yang

Integration of artificial intelligent (AI) agents in higher education is transforming teaching, learning and administrative processes. Although existing AI agents effectively support individual tasks, their implementation remains fragmented…

Artificial Intelligence · Computer Science 2026-05-15 Vidya K Sudarshan , Anushka Sisodia , Reshma A Ramachandra , Sia Batra , Josephine Chong Leng Leng

Recent progress in Large Language Models (LLMs) has drawn attention to their potential for accelerating drug discovery. However, a central problem remains: translating theoretical ideas into robust implementations in the highly specialized…

Machine Learning · Computer Science 2025-03-06 Sizhe Liu , Yizhou Lu , Siyu Chen , Xiyang Hu , Jieyu Zhao , Yingzhou Lu , Yue Zhao

The Science Consultant Agent is a web-based Artificial Intelligence (AI) tool that helps practitioners select and implement the most effective modeling strategy for AI-based solutions. It operates through four core components:…

Artificial Intelligence · Computer Science 2025-12-19 Karthikeyan K , Philip Wu , Xin Tang , Alexandre Alves

Deep research has emerged as a transformative capability for autonomous agents, empowering Large Language Models to navigate complex, open-ended tasks. However, realizing its full potential is hindered by critical limitations, including…

Computation and Language · Computer Science 2026-01-28 Yuxuan Cai , Xinyi Lai , Peng Yuan , Weiting Liu , Huajian Li , Mingda Li , Xinghua Wang , Shengxie Zheng , Yanchao Hao , Yuyang Yin , Zheng Wei

The rapid spread of misinformation in the digital era poses significant challenges to public discourse, necessitating robust and scalable fact-checking solutions. Traditional human-led fact-checking methods, while credible, struggle with…

Artificial Intelligence · Computer Science 2025-06-24 Tam Trinh , Manh Nguyen , Truong-Son Hy

AI agents are increasingly used to solve complex, multi-step tasks, but existing multi-agent frameworks remain brittle as workflows grow in scale and depth. Small errors at intermediate stages can propagate through agent interactions, while…

Artificial Intelligence · Computer Science 2026-05-26 Andy Xu , Yu-Wing Tai

Building Large Language Model agents that expand their capabilities by interacting with external tools represents a new frontier in AI research and applications. In this paper, we introduce InfoAgent, a deep research agent powered by an…

Saving, or checkpointing, intermediate results during interactive data exploration can potentially boost user productivity. However, existing studies on this topic are limited, as they primarily rely on small-scale experiments with human…

Human-Computer Interaction · Computer Science 2025-04-03 Hanxi Fang , Supawit Chockchowwat , Hari Sundaram , Yongjoo Park