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Scientific research follows multi-turn, multi-step workflows that require proactively searching the literature, consulting figures and tables, and integrating evidence across papers to align experimental settings and support reproducible…

Computation and Language · Computer Science 2026-04-08 Xuan Dong , Huanyang Zheng , Tianhao Niu , Zhe Han , Pengzhan Li , Bofei Liu , Zhengyang Liu , Guancheng Li , Qingfu Zhu , Wanxiang Che

Given the remarkable performance of Large Language Models (LLMs), an important question arises: Can LLMs conduct human-like scientific research and discover new knowledge, and act as an AI scientist? Scientific discovery is an iterative…

Machine Learning · Computer Science 2025-02-24 Tingting Chen , Srinivas Anumasa , Beibei Lin , Vedant Shah , Anirudh Goyal , Dianbo Liu

One of the grand challenges of artificial general intelligence is developing agents capable of conducting scientific research and discovering new knowledge. While frontier models have already been used as aides to human scientists, e.g. for…

Artificial Intelligence · Computer Science 2024-09-04 Chris Lu , Cong Lu , Robert Tjarko Lange , Jakob Foerster , Jeff Clune , David Ha

Computing has long served as a cornerstone of scientific discovery. Recently, a paradigm shift has emerged with the rise of large language models (LLMs), introducing autonomous systems, referred to as agents, that accelerate discovery…

We introduce the concept of "Design Agents" for engineering applications, particularly focusing on the automotive design process, while emphasizing that our approach can be readily extended to other engineering and design domains. Our…

Artificial Intelligence · Computer Science 2025-12-04 Mohamed Elrefaie , Janet Qian , Raina Wu , Qian Chen , Angela Dai , Faez Ahmed

We present an agent-driven approach to the construction of parameter inference pipelines for scientific data analysis. Our method leverages a multi-agent system, Cmbagent (the analysis system of the AI scientist Denario), in which…

Artificial Intelligence · Computer Science 2026-04-14 Thomas Borrett , Licong Xu , Andy Nilipour , Boris Bolliet , Sebastien Pierre , Erwan Allys , Celia Lecat , Biwei Dai , Po-Wen Chang , Wahid Bhimji

We present \textbf{Deep Researcher Agent}, an open-source framework that enables large language model (LLM) agents to autonomously conduct deep learning experiments around the clock. Unlike existing AI research assistants that focus on…

Artificial Intelligence · Computer Science 2026-04-08 Xiangyue Zhang

This paper introduces a methodology based on agentic workflows for economic research that leverages Large Language Models (LLMs) and multimodal AI to enhance research efficiency and reproducibility. Our approach features autonomous and…

General Economics · Economics 2025-04-15 Herbert Dawid , Philipp Harting , Hankui Wang , Zhongli Wang , Jiachen Yi

Deep research agents powered by Large Language Models (LLMs) can perform multi-step reasoning, web exploration, and long-form report generation. However, most existing systems operate in an autonomous manner, assuming fully specified user…

Computation and Language · Computer Science 2026-01-13 Yingchaojie Feng , Qiang Huang , Xiaoya Xie , Zhaorui Yang , Jun Yu , Wei Chen , Anthony K. H. Tung

The convergence of artificial intelligence and materials science presents a transformative opportunity, but achieving true acceleration in discovery requires moving beyond task-isolated, fine-tuned models toward agentic systems that plan,…

Systematic reviews (SRs) are vital for evidence-based practice in high stakes disciplines, such as healthcare, but are often impeded by intensive labors and lengthy processes that can take months to complete. Due to the high demand for…

Human-Computer Interaction · Computer Science 2025-06-03 Rui Qiu , Shijie Chen , Yu Su , Po-Yin Yen , Han-Wei Shen

The primary goal of this study is to analyze agentic workflows in education according to the proposed four major technological paradigms: reflection, planning, tool use, and multi-agent collaboration. We critically examine the role of AI…

Artificial Intelligence · Computer Science 2026-01-27 Firuz Kamalov , David Santandreu Calonge , Linda Smail , Dilshod Azizov , Dimple R. Thadani , Theresa Kwong , Amara Atif

Background: Large language models are typically evaluated as models, benchmarks, or short conversational episodes. Less is known about what happens when an agent is embedded persistently in a real academic research environment with durable…

Multiagent Systems · Computer Science 2026-05-27 Anas H. Alzahrani

Large language models hold promise as scientific assistants, yet existing agents either rely solely on algorithm evolution or on deep research in isolation, both of which face critical limitations. Pure algorithm evolution, as in…

Artificial Intelligence · Computer Science 2025-10-08 Gang Liu , Yihan Zhu , Jie Chen , Meng Jiang

The exponential growth of academic publications has led to a surge in papers of varying quality, increasing the cost of paper screening. Current approaches either use novelty assessment within general AI Reviewers or repurpose DeepResearch,…

Computation and Language · Computer Science 2026-03-24 Jiajun Hou , Hexuan Deng , Wenxiang Jiao , Xuebo Liu , Xiaopeng Ke , Min Zhang

While AI for Science (AI4S) serves as an analytical tool in the current research paradigm, it doesn't solve its core inefficiency. We propose "Agent for Science" (Agent4S)-the use of LLM-driven agents to automate the entire research…

Artificial Intelligence · Computer Science 2025-07-01 Boyuan Zheng , Zerui Fang , Zhe Xu , Rui Wang , Yiwen Chen , Cunshi Wang , Mengwei Qu , Lei Lei , Zhen Feng , Yan Liu , Yuyang Li , Mingzhou Tan , Jiaji Wu , Jianwei Shuai , Jia Li , Fangfu Ye

Recent advances in AI agents for software engineering and scientific discovery have demonstrated remarkable capabilities, yet their application to developing novel ranking models in commercial search engines remains unexplored. In this…

Information Retrieval · Computer Science 2026-03-25 Liwei Wu , Cho-Jui Hsieh

Conventional biomedical research is increasingly labor-intensive due to the exponential growth of scientific literature and datasets. Artificial intelligence (AI), particularly Large Language Models (LLMs), has the potential to…

Multiagent Systems · Computer Science 2025-07-08 Yi Luo , Linghang Shi , Yihao Li , Aobo Zhuang , Yeyun Gong , Ling Liu , Chen Lin

DeepResearch agents represent a transformative AI paradigm, conducting expert-level research through sophisticated reasoning and multi-tool integration. However, evaluating these systems remains critically challenging due to open-ended…

Artificial Intelligence · Computer Science 2025-10-10 Tianyu Fan , Xinyao Niu , Yuxiang Zheng , Fengji Zhang , Chengen Huang , Bei Chen , Junyang Lin , Chao Huang

We introduce the AI co-mathematician, a workbench for mathematicians to interactively leverage AI agents to pursue open-ended research. The AI co-mathematician is optimized to provide holistic support for the exploratory and iterative…

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