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The surge of large language models (LLMs) has driven significant progress in medical applications, including traditional Chinese medicine (TCM). However, current medical LLMs struggle with TCM diagnosis and syndrome differentiation due to…

Computation and Language · Computer Science 2025-10-01 Sibo Wei , Xueping Peng , Yi-Fei Wang , Tao Shen , Jiasheng Si , Weiyu Zhang , Fa Zhu , Athanasios V. Vasilakos , Wenpeng Lu , Xiaoming Wu , Yinglong Wang

While virtual reality (VR) excels at simulating physical environments, its effectiveness for training complex interpersonal skills is limited by a lack of psychologically plausible virtual humans. This gap is particularly critical in…

Large language models (LLMs) are increasingly used as simulated participants in social science experiments, but their behavior is often unstable and highly sensitive to design choices. Prior evaluations frequently conflate base-model…

Artificial Intelligence · Computer Science 2026-02-03 Xuan Liu , Haoyang Shang , Zizhang Liu , Xinyan Liu , Yunze Xiao , Yiwen Tu , Haojian Jin

Large language models (LLMs) and LLM-based agents are increasingly deployed as assistants in planning and decision making, yet most existing systems are implicitly optimized for a single-principal interaction paradigm, in which the model is…

Computation and Language · Computer Science 2026-04-29 Shu Yang , Shenzhe Zhu , Hao Zhu , José Ramón Enríquez , Di Wang , Alex Pentland , Michiel A. Bakker , Jiaxin Pei

Clinical diagnosis begins with doctor-patient interaction, during which physicians iteratively gather information, determine examination and refine differential diagnosis through patients' response. This dynamic clinical-reasoning process…

Computation and Language · Computer Science 2025-12-30 Yuqi Tang , Jing Yu , Zichang Su , Kehua Feng , Zhihui Zhu , Libin Wang , Lei Liang , Qiang Zhang , Keyan Ding , Huajun Chen

Medical education faces challenges in providing scalable, consistent clinical skills training. Simulation with standardized patients (SPs) develops communication and diagnostic skills but remains resource-intensive and variable in feedback…

Using large language models (LLMs) to assist psychological counseling is a significant but challenging task at present. Attempts have been made on improving empathetic conversations or acting as effective assistants in the treatment with…

Computation and Language · Computer Science 2024-06-11 Chenhao Zhang , Renhao Li , Minghuan Tan , Min Yang , Jingwei Zhu , Di Yang , Jiahao Zhao , Guancheng Ye , Chengming Li , Xiping Hu

Despite the impressive capabilities of Large Language Models (LLMs), existing Conversational Health Agents (CHAs) remain static and brittle, incapable of adaptive multi-turn reasoning, symptom clarification, or transparent decision-making.…

Computation and Language · Computer Science 2025-07-11 Xinyi Liu , Dachun Sun , Yi R. Fung , Dilek Hakkani-Tür , Tarek Abdelzaher

Large language models (LLMs) can generate fluent dialogue, but prior works lack situational grounding, dynamic strategy control, and evaluation aligned with clinical standards in motivational interviewing (MI). We introduce StoryMI, a…

Computation and Language · Computer Science 2026-05-28 Qingyu Meng , Min Chen , Dingming Liu , Yifan Mo , Yue Su , Xin Sun , Koen Hindriks , Jiahuan Pei

As mental health issues rise among college students, there is an increasing interest and demand in leveraging Multimodal Language Models (MLLM) to enhance mental support services, yet integrating them into psychotherapy remains theoretical…

Human-Computer Interaction · Computer Science 2026-02-09 Jiyao Wang , Youyu Sheng , Qihang He , Zian Zhang , Haolong Hu , Yumei Jing , Dengbo He

Simulating step-wise human behavior with Large Language Models (LLMs) has become an emerging research direction, enabling applications in various practical domains. While prior methods, including prompting, supervised fine-tuning (SFT), and…

Computation and Language · Computer Science 2025-10-21 Ziyi Wang , Yuxuan Lu , Yimeng Zhang , Jing Huang , Dakuo Wang

The reliable evaluation of large language models (LLMs) in medical applications remains an open challenge, particularly in capturing the complexity of multi-turn doctor-patient interactions that unfold in real clinical environments.…

Artificial Intelligence · Computer Science 2025-10-15 Yuechun Yu , Han Ying , Haoan Jin , Wenjian Jiang , Dong Xian , Binghao Wang , Zhou Yang , Mengyue Wu

Recent advancements in Large Language Models (LLMs) have significantly enhanced conversational agents, making them applicable to various fields (e.g., education, entertainment). Despite their progress, the evaluation of the agents often…

Computation and Language · Computer Science 2025-09-29 Jiho Kim , Woosog Chay , Hyeonji Hwang , Daeun Kyung , Hyunseung Chung , Eunbyeol Cho , Yeonsu Kwon , Yohan Jo , Edward Choi

Numerous medical systems powered by Large Language Models (LLMs) have achieved remarkable progress in diverse healthcare tasks. However, research on their medication safety remains limited due to the lack of real world datasets, constrained…

Artificial Intelligence · Computer Science 2025-11-07 Jiahao Zhao , Luxin Xu , Minghuan Tan , Lichao Zhang , Ahmadreza Argha , Hamid Alinejad-Rokny , Min Yang

As large language models (LLMs) advance in conversational and reasoning capabilities, their practical application in healthcare has become a critical research focus. However, there is a notable gap between the performance of medical LLMs on…

Individual prevention behaviors are a primary line of defense during the early stages of novel infectious disease outbreaks, yet their adoption is heterogeneous and difficult to forecast-especially when empirical data are scarce and…

Social and Information Networks · Computer Science 2026-01-08 Lujia Bo , Mingxuan Chen , Youduo Chen , Xiaofan Gui , Jiang Bian , Chunyan Wang , Yi Liu

This research focuses on using large language models (LLMs) to simulate social experiments, exploring their ability to emulate human personality in virtual persona role-playing. The research develops an end-to-end evaluation framework,…

Computers and Society · Computer Science 2025-10-15 Yuqi Bai , Tianyu Huang , Kun Sun , Yuting Chen

Large Language Models (LLMs) are increasingly used to simulate human users in interactive settings such as therapy, education, and social role-play. While these simulations enable scalable training and evaluation of AI agents, off-the-shelf…

Computation and Language · Computer Science 2025-11-04 Marwa Abdulhai , Ryan Cheng , Donovan Clay , Tim Althoff , Sergey Levine , Natasha Jaques

Standardized patients (SPs) are indispensable for clinical skills training but remain expensive and difficult to scale. Although large language model (LLM)-based virtual standardized patients (VSPs) have been proposed as an alternative,…

Computation and Language · Computer Science 2026-03-24 Bingquan Zhang , Xiaoxiao Liu , Yuchi Wang , Lei Zhou , Qianqian Xie , Benyou Wang

The advent of the Internet era has led to an explosive growth in the Electronic Health Records (EHR) in the past decades. The EHR data can be regarded as a collection of clinical events, including laboratory results, medication records,…

Machine Learning · Computer Science 2019-11-14 Zichang Wang , Haoran Li , Luchen Liu , Haoxian Wu , Ming Zhang
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