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Complex clinical decision making often fails not because a model lacks facts, but because it cannot reliably select and apply the right procedural knowledge and the right prior example at the right reasoning step. We frame clinical question…

Information Retrieval · Computer Science 2026-03-03 Junda Wang , Zonghai Tao , Hansi Zeng , Zhichao Yang , Hamed Zamani , Hong Yu

Medical imaging has revolutionized diagnosis, yet unnecessary procedures are rising, exposing patients to radiation and stress, limiting equitable access, and straining healthcare systems. The American College of Radiology Appropriateness…

Quantitative Methods · Quantitative Biology 2025-10-08 Anni Tziakouri , Filippo Menolascina

Large Language Models (LLMs) and multi-agent systems have shown impressive capabilities in natural language tasks but face challenges in clinical trial applications, primarily due to limited access to external knowledge. Recognizing the…

Computation and Language · Computer Science 2024-07-23 Ling Yue , Sixue Xing , Jintai Chen , Tianfan Fu

The reliability of clinical artificial intelligence (AI) depends on high-quality data, yet Electronic Health Records are often inconsistent with existing scientific knowledge. Current quality assessments are limited: they either focus on…

Machine Learning · Computer Science 2026-05-26 Irena Girshovitz , Atai Ambus , Moni Shahar , Ran Gilad-Bachrach

Medical vision-language models (VLMs) and AI agents have made significant progress in learning to analyze and reason about clinical images. However, existing medical visual question answering (VQA) benchmarks collapse model capabilities…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Yixiong Chen , Wenjie Xiao , Pedro R. A. S. Bassi , Boyan Wang , Liang He , Xinze Zhou , Sezgin Er , Ibrahim Ethem Hamamci , Zongwei Zhou , Alan Yuille

Current agentic AI benchmarks predominantly evaluate task completion accuracy, while overlooking critical enterprise requirements such as cost-efficiency, reliability, and operational stability. Through systematic analysis of 12 main…

Artificial Intelligence · Computer Science 2025-11-19 Sushant Mehta

Large Language Models (LLMs) have achieved remarkable advancements in natural language processing tasks, yet they encounter challenges in complex decision-making scenarios that require long-term reasoning and alignment with high-level…

Computation and Language · Computer Science 2025-06-10 Heng Dong , Kefei Duan , Chongjie Zhang

Access to the right evidence does not guarantee that large language models (LLMs) will reason with it correctly. This gap between retrieval and reasoning is especially concerning in clinical settings, where outputs must align with…

Artificial Intelligence · Computer Science 2025-11-21 Deepthi Potluri , Aby Mammen Mathew , Jeffrey B DeWitt , Alexander L. Rasgon , Yide Hao , Junyuan Hong , Ying Ding

With the advancement of Agentic AI, researchers are increasingly leveraging autonomous agents to address challenges in software engineering (SE). However, the large language models (LLMs) that underpin these agents often function as black…

Software Engineering · Computer Science 2026-04-03 Jingyue Li , André Storhaug

With the increasing demand for step-wise, cross-modal, and knowledge-grounded reasoning, multimodal large language models (MLLMs) are evolving beyond the traditional fixed retrieve-then-generate paradigm toward more sophisticated agentic…

Artificial Intelligence · Computer Science 2026-03-03 Xuying Ning , Dongqi Fu , Tianxin Wei , Mengting Ai , Jiaru Zou , Ting-Wei Li , Hanghang Tong , Yada Zhu , Hendrik Hamann , Jingrui He

Large Language Models (LLMs) have shown promising performance in time series modeling tasks, but do they truly understand time series data? While multiple benchmarks have been proposed to answer this fundamental question, most are manually…

Artificial Intelligence · Computer Science 2026-04-15 Malgorzata Gwiazda , Yifu Cai , Mononito Goswami , Arjun Choudhry , Artur Dubrawski

Large language model (LLM)-based systems are increasingly deployed to conduct scientific research autonomously, yet whether their reasoning adheres to the epistemic norms that make scientific inquiry self-correcting is poorly understood.…

AI agent research spans a wide spectrum: from RL agents that learn from scratch to foundation model agents that leverage pre-trained knowledge, yet no unified benchmark enables fair comparison across these approaches. We present Agentick, a…

Artificial Intelligence · Computer Science 2026-05-14 Roger Creus Castanyer , Pablo Samuel Castro , Glen Berseth

Process-Level Reward Models (PRMs) are essential for guiding complex reasoning in large language models, yet existing PRM benchmarks cover only general domains such as mathematics, failing to address medical reasoning -- which is uniquely…

Computation and Language · Computer Science 2026-04-21 Lingyan Wu , Xiang Zheng , Weiqi Zhai , Wei Wang , Xuan Ren , Zifan Zhang , Hu Wei , Bing Zhao

The integration of artificial intelligence (AI) into medical diagnostic workflows requires robust and consistent evaluation methods to ensure reliability, clinical relevance, and the inherent variability in expert judgments. Traditional…

This benchmark suite provides a comprehensive evaluation framework for assessing both individual LLMs and multi-agent systems in Real-world planning and scheduling scenarios. The suite encompasses 14 designed planning and scheduling…

Artificial Intelligence · Computer Science 2025-08-06 Longling Geng , Edward Y. Chang

The integration of Large Language Models (LLMs) into healthcare is constrained by knowledge limitations, hallucinations, and a disconnect from Evidence-Based Medicine (EBM). While Retrieval-Augmented Generation (RAG) offers a solution,…

Computation and Language · Computer Science 2026-02-03 Qiaoyu Zheng , Yuze Sun , Chaoyi Wu , Weike Zhao , Pengcheng Qiu , Yongguo Yu , Kun Sun , Jian Zhang , Yanfeng Wang , Ya Zhang , Weidi Xie

Large language model (LLM)-based AI agents are increasingly capable of complex clinical reasoning and may soon participate in medical decision-making with limited or no real-time human oversight. This shift raises fundamental questions…

Computers and Society · Computer Science 2026-03-17 Tom Bisson , Henriette Voelker , Sanddhya Jayabalan , A John Iafrate , Jakob N Kather , Jochen K Lennerz

Large Language Models (LLMs) have achieved strong performance on static reasoning benchmarks, yet their effectiveness as interactive agents operating in adversarial, time-sensitive environments remains poorly understood. Existing…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Yang Li , Xing Chen , Yutao Liu , Gege Qi , Yanxian BI , Zizhe Wang , Yunjian Zhang , Yao Zhu

Clinical coding is crucial for healthcare billing and data analysis. Manual clinical coding is labour-intensive and error-prone, which has motivated research towards full automation of the process. However, our analysis, based on US English…

Computation and Language · Computer Science 2025-06-19 Yidong Gan , Maciej Rybinski , Ben Hachey , Jonathan K. Kummerfeld