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Large language models (LLMs) have shown promise in medical question answering but often struggle with hallucinations and shallow reasoning, particularly in tasks requiring nuanced clinical understanding. Retrieval-augmented generation (RAG)…

Computation and Language · Computer Science 2025-08-25 Ziyu Wang , Elahe Khatibi , Amir M. Rahmani

While large language models (LLMs) achieve near-perfect scores on medical licensing exams, these evaluations inadequately reflect the complexity and diversity of real-world clinical practice. We introduce MedHELM, an extensible evaluation…

We present PULSE, a medical reasoning agent that combines a domain-tuned large language model with scientific literature retrieval to support diagnostic decision-making in complex real-world cases. To evaluate its capabilities, we curated a…

Computation and Language · Computer Science 2026-03-19 Zhongzhen Huang , Yan Ling , Hong Chen , Ye Feng , Li Wu , Linjie Mu , Shaoting Zhang , Xiaofan Zhang , Kun Qian , Xiaomu Li

Large Language Models (LLMs) are becoming increasingly powerful and capable of handling complex tasks, e.g., building single agents and multi-agent systems. Compared to single agents, multi-agent systems have higher requirements for the…

Computation and Language · Computer Science 2024-08-29 Wei Wang , Dan Zhang , Tao Feng , Boyan Wang , Jie Tang

Automated Program Repair (APR) agents leverage Large Language Models (LLMs) to autonomously diagnose and fix software bugs through reasoning, planning, and tool use. Despite impressive leaderboard gains on benchmarks such as SWE-bench,…

Software Engineering · Computer Science 2026-05-28 Ira Ceka , Hailie Mitchell , Saurabh Pujar , Luca Buratti , Shyam Ramji , Junfeng Yang , Gail Kaiser , Baishakhi Ray

We present L-MARS (Legal Multi-Agent Workflow with Orchestrated Reasoning and Agentic Search), a multi-agent retrieval framework for grounded legal question answering that decomposes queries into structured sub-problems, retrieves evidence…

Artificial Intelligence · Computer Science 2026-03-31 Ziqi Wang , Boqin Yuan

Although artificial intelligence (AI) shows growing promise for mental health care, current approaches to evaluating AI tools in this domain remain fragmented and poorly aligned with clinical practice, social context, and first-hand user…

As large language model (LLM)-based agents become increasingly integrated into daily digital interactions, their ability to reason across long interaction histories becomes crucial for providing personalized and contextually aware…

Machine Learning · Computer Science 2025-12-05 Andy Chung , Yichi Zhang , Kaixiang Lin , Aditya Rawal , Qiaozi Gao , Joyce Chai

Large language models (LLMs), including zero-shot and few-shot paradigms, have shown promising capabilities in clinical text generation. However, real-world applications face two key challenges: (1) patient data is highly unstructured,…

Computation and Language · Computer Science 2025-07-10 Garapati Keerthana , Manik Gupta

We present EHRMIND, a practical recipe for adapting large language models (LLMs) to complex clinical reasoning tasks using reinforcement learning with verifiable rewards (RLVR). While RLVR has succeeded in mathematics and coding, its…

Computation and Language · Computer Science 2025-06-02 Jiacheng Lin , Zhenbang Wu , Jimeng Sun

The rapid adoption of AI agents across domains has made systematic evaluation crucial for ensuring their usefulness and successful production deployment. Evaluation of AI agents typically involves using a fixed set of benchmarks and…

Recent advances in large language models (LLMs) have enabled the emergence of general-purpose agents for automating end-to-end machine learning (ML) workflows, including data analysis, feature engineering, model training, and competition…

Artificial Intelligence · Computer Science 2025-09-12 Hangyi Jia , Yuxi Qian , Hanwen Tong , Xinhui Wu , Lin Chen , Feng Wei

Retrieval-Augmented Generation (RAG) is widely employed to mitigate risks such as hallucinations and knowledge obsolescence in medical question answering, yet its predominantly single-round, static retrieval paradigm misaligns with the…

Computation and Language · Computer Science 2026-05-19 Yongfeng Huang , Ruiying Chen , James Cheng

Evaluating AI agents that solve real-world tasks through function-call sequences remains an open challenge. Existing agentic benchmarks often reduce evaluation to a binary judgment of the final state, overlooking critical aspects such as…

Artificial Intelligence · Computer Science 2025-09-26 Panagiotis Michelakis , Yiannis Hadjiyiannis , Dimitrios Stamoulis

Existing multimodal retrieval benchmarks largely emphasize semantic matching on daily-life images and offer limited diagnostics of professional knowledge and complex reasoning. To address this gap, we introduce ARK, a benchmark designed to…

Computer Vision and Pattern Recognition · Computer Science 2026-02-11 Yijie Lin , Guofeng Ding , Haochen Zhou , Haobin Li , Mouxing Yang , Xi Peng

Large language models (LLMs) have demonstrated notable potential in medical applications, yet they face substantial challenges in handling complex real-world clinical diagnoses using conventional prompting methods. Current prompt…

Artificial Intelligence · Computer Science 2026-03-02 Wenliang Li , Rui Yan , Xu Zhang , Li Chen , Hongji Zhu , Jing Zhao , Junjun Li , Mengru Li , Wei Cao , Zihang Jiang , Wei Wei , Kun Zhang , Shaohua Kevin Zhou

User-generated texts available on the web and social platforms are often long and semantically challenging, making them difficult to annotate. Obtaining human annotation becomes increasingly difficult as problem domains become more…

Computation and Language · Computer Science 2023-09-19 Joseph Gatto , Sarah M. Preum

Large language models (LLMs) have demonstrated promising performance on medical benchmarks; however, their ability to perform medical calculations, a crucial aspect of clinical decision-making, remains underexplored and poorly evaluated.…

Computation and Language · Computer Science 2026-02-03 Benlu Wang , Iris Xia , Yifan Zhang , Junda Wang , Feiyun Ouyang , Shuo Han , Arman Cohan , Hong Yu , Zonghai Yao

Recent advancements in Large Language Models (LLMs) have catalyzed a paradigm shift from static prediction systems to agentic AI agents capable of reasoning, interacting with tools, and adapting to complex tasks. While LLM-based agentic…

Computer Vision and Pattern Recognition · Computer Science 2025-07-24 Nima Fathi , Amar Kumar , Tal Arbel

There are two main barriers to using large language models (LLMs) in clinical reasoning. Firstly, while LLMs exhibit significant promise in Natural Language Processing (NLP) tasks, their performance in complex reasoning and planning falls…

Artificial Intelligence · Computer Science 2024-12-31 Shengxin Hong , Liang Xiao , Xin Zhang , Jianxia Chen