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Agentic AI systems are increasingly capable of autonomous data science workflows, yet clinical prediction tasks demand domain expertise that purely automated approaches struggle to provide. We investigate how human guidance of agentic AI…

While large language models are capable diagnostic tools, the impact of multi-agent topology on diagnostic accuracy remains underexplored. This study evaluates four agent topologies, Control (single agent), Hierarchical, Adversarial, and…

Multiagent Systems · Computer Science 2026-03-10 Ahmed Almasoud

As autonomous AI agents are increasingly deployed in high-stakes environments, ensuring their safety and alignment with human values is becoming a practical deployment concern. Current benchmarks for AI agents primarily evaluate refusal of…

Artificial Intelligence · Computer Science 2026-05-12 Miles Q. Li , Benjamin C. M. Fung , Martin Weiss , Pulei Xiong , Khalil Al-Hussaeni , Claude Fachkha

Screening patients for clinical trial eligibility remains a manual, time-consuming, and resource-intensive process. We present a secure, scalable proof-of-concept system for Artificial Intelligence (AI)-augmented patient-trial matching that…

Complex medical reasoning has historically required frontier language models to achieve clinically-acceptable accuracy, creating computational barriers that limit deployment in resource-constrained clinical settings. We present…

Artificial Intelligence · Computer Science 2026-04-01 Pranav Pushkar Mishra , Mohammad Arvan , Mohan Zalake

The growing capabilities of large language models (LLMs) in instruction-following and context-understanding lead to the era of agents with numerous applications. Among these, task planning agents have become especially prominent in…

The increasing use of large language models in mental health applications calls for principled evaluation frameworks that assess alignment with psychotherapeutic best practices beyond surface-level fluency. While recent systems exhibit…

Computation and Language · Computer Science 2026-04-15 Abdullah Mazhar , Het Riteshkumar Shah , Aseem Srivastava , Smriti Joshi , Md Shad Akhtar

Artificial intelligence has significantly advanced healthcare, particularly through large language models (LLMs) that excel in medical question answering benchmarks. However, their real-world clinical application remains limited due to the…

Computation and Language · Computer Science 2024-07-01 Zhihao Fan , Jialong Tang , Wei Chen , Siyuan Wang , Zhongyu Wei , Jun Xi , Fei Huang , Jingren Zhou

Language models (LMs) represent an emerging paradigm within artificial intelligence, with applications throughout the medical enterprise. A comprehensive understanding of the clinical task and awareness of the variability in performance…

Machine Learning · Computer Science 2026-03-09 Victor Garcia , Mariia Sidulova , Aldo Badano

Legal judgments may contain errors due to the complexity of case circumstances and the abstract nature of legal concepts, while existing appellate review mechanisms face efficiency pressures from a surge in case volumes. Although current…

Computation and Language · Computer Science 2026-02-02 Yifei Li , Richong Zhang , Wanyu Tu , Zhijie Nie , Haokun Luo , Chuantao Yin , Pengchong Li

AI agents hold the potential to revolutionize scientific productivity by automating literature reviews, replicating experiments, analyzing data, and even proposing new directions of inquiry; indeed, there are now many such agents, ranging…

As Large Language Models (LLMs) have become integral to both research and daily operations, rigorous evaluation is crucial. This assessment is important not only for individual tasks but also for understanding their societal impact and…

Software Engineering · Computer Science 2024-04-02 Zeeshan Rasheed , Muhammad Waseem , Kari Systä , Pekka Abrahamsson

Large language models (LLMs) are increasingly used in scientific domains. While they can produce reasoning-like content via methods such as chain-of-thought prompting, these outputs are typically unstructured and informal, obscuring whether…

Artificial Intelligence · Computer Science 2025-11-18 Pengze Li , Jiaqi Liu , Junchi Yu , Lihao Liu , Mingyu Ding , Wanli Ouyang , Shixiang Tang , Xi Chen

Large Language Models (LLMs) are powerful candidates for complex decision-making, leveraging vast encoded knowledge and remarkable zero-shot abilities. However, their adoption in high-stakes environments is hindered by their opacity; their…

Artificial Intelligence · Computer Science 2026-01-12 Sahil Wadhwa , Himanshu Kumar , Guanqun Yang , Abbaas Alif Mohamed Nishar , Pranab Mohanty , Swapnil Shinde , Yue Wu

Healthcare and medicine are multimodal disciplines that deal with multimodal data for reasoning and diagnosing multiple diseases. Although some multimodal reasoning models have emerged for reasoning complex tasks in scientific domains,…

Artificial Intelligence · Computer Science 2025-09-16 Susanta Mitra

Modern agents powered by thinking LLMs achieve high accuracy through long chain-of-thought reasoning but incur substantial inference costs. While many LLMs now support configurable reasoning levels (e.g., high/medium/low), static strategies…

Artificial Intelligence · Computer Science 2026-03-10 Jingbo Yang , Bairu Hou , Wei Wei , Yujia Bao , Shiyu Chang

Artificial intelligence agents are increasingly capable of performing complex tasks across various domains. As these agents advance, there is a growing need to accurately measure and benchmark their capabilities, particularly in…

Artificial Intelligence · Computer Science 2024-10-31 Matthew Kenney

Modern Artificial Intelligence (AI) increasingly relies on multi-agent architectures that blend visual and language understanding. Yet, a pressing challenge remains: How can we trust these agents especially in zero-shot settings with no…

Artificial Intelligence · Computer Science 2025-09-23 Konstantinos I. Roumeliotis , Ranjan Sapkota , Manoj Karkee , Nikolaos D. Tselikas

We present Collaborative Agent Reasoning Engineering (CARE), a disciplined methodology for engineering Large Language Model (LLM) agents in scientific domains. Unlike ad-hoc trial-and-error approaches, CARE specifies behavior, grounding,…

Artificial Intelligence · Computer Science 2026-05-01 Rahul Ramachandran , Nidhi Jha , Muthukumaran Ramasubramanian

Agentic AI represents a major shift in how autonomous systems reason, plan, and execute multi-step tasks through the coordination of Large Language Models (LLMs), Vision Language Models (VLMs), tools, and external services. While these…

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