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This work deals with the viscoelasticity of the arterial wall and its influence on the pulse waves. We describe the viscoelasticity by a non-linear Kelvin-Voigt model in which the coefficients are fitted using experimental time series of…
This paper presents a recurrent neural network approach to simulating mechanical ventilator pressure. The traditional mechanical ventilator has a control pressure that is monitored by a medical practitioner and can behave incorrectly if the…
This article presents experimental and numerical studies on the effect of free stream turbulence on evolution of flow over an autonomous underwater vehicle (AUV) hull form at three Reynolds numbers with different submergence depths and…
Introduction There is increasing focus on the association between trunk control and functional abilities in children with cerebral palsy (CP). The purpose of this study was to determine the extent of functional change in children with CP…
The acute respiratory distress syndrome (ARDS) is characterized by the acute development of diffuse alveolar damage (DAD) resulting in increased vascular permeability and decreased alveolar gas exchange. Mechanical ventilation is a…
Respiratory motion complicates accurate irradiation of thoraco-abdominal tumors during radiotherapy, as treatment-system latency entails target-location uncertainties. This work addresses frame forecasting in chest and liver cine MRI to…
Background: Trans-spinal FUS (tsFUS) has recently been shown promise in modulating spinal reflexes in rodents, opening new avenues for spinal cord interventions in motor control and pain management. However, anatomical differences between…
Continuous outcome measurements truncated by death present a challenge for the estimation of unbiased treatment effects in randomized controlled trials (RCTs). One way to deal with such situations is to estimate the survivor average causal…
There has become of increasing interest in transcranial alternating current stimulation (tACS) since its inception nearly a decade ago. tACS in modulating brain state is an active area of research and has been demonstrated effective in…
Physics-based 0D reduced-order models provide computationally lightweight predictions of cardiovascular flows, resolving bulk hemodynamics in fractions of a second that would take days to solve using traditional 3D finite-element…
Spatial patterns of elevated wall shear stress and pressure due to blood flow past aortic stenosis (AS) are studied using GPU-accelerated patient-specific computational fluid dynamics. Three cases of moderate AS, one with a dilated…
Detection and monitoring of patients with pulmonary hypertension, defined as mean blood pressure in the main pulmonary artery above 25 mmHg, requires a combination of imaging and hemodynamic measurements. This study demonstrates how to…
Non-rigid registration is a key component in soft-tissue navigation. We focus on laparoscopic liver surgery, where we register the organ model obtained from a preoperative CT scan to the intraoperative partial organ surface, reconstructed…
The influence of transversely oriented sinusoidal wall corrugation on an incompressible isothermal flow in the near-wall region, subjected to adverse pressure gradient conditions at a friction Reynolds number of $Re_{\tau} = 2500$, is…
Background: Pregnancy-associated thrombotic microangiopathy (P-TMA) is rare but life-threatening. Early risk prediction before overt clinical presentation remains challenging, as the associated laboratory abnormalities are subtle,…
Generalisability and the consistency of the a posteriori results are the most critical points of view regarding data-driven turbulence models. This study presents a progressive improvement of turbulence models using simulation-driven…
Blood coagulation is governed by tightly regulated reaction networks that unfold within a flowing, heterogeneous microvascular environment. Reduced kinetic models of the intrinsic and extrinsic pathways have seen limited in vitro…
T-wave alternans (TWA) is a potential marker for sudden cardiac death, but its reliable analysis is often constrained to noise-free environments, limiting its utility in real-world settings. We explore model-based T-wave estimation to…
Some existing models of the atherosclerosis development are discussed and a new improved mathematical model, which takes into account new experimental results about diverse roles of macrophages in atherosclerosis, is proposed. Using technic…
Objective: Triaxial accelerometers (TAAs) are widely used in homecare medicine. This study investigates whether TAA signals recorded at the fingertip encode respiratory information, particularly instantaneous respiratory rate (IRR) and…