Related papers: Simulations Predict Improved Valve Performance Wit…
Functional limitation after lung resection surgery has been consistently documented in clinical studies, and right ventricle (RV) dysfunction has been hypothesized as a contributing reason. However, the mechanisms of RV dysfunction after…
Establishing patient-specific finite element analysis (FEA) models for computational fluid dynamics (CFD) of double stenosed artery models involves time and effort, restricting physicians' ability to respond quickly in time-critical medical…
Background: Pleural Effusions (PE) is a common finding in many different clinical conditions, but accurately measuring their volume from CT scans is challenging. Purpose: To improve PE segmentation and quantification for enhanced clinical…
Well-resolved direct numerical simulations (DNSs) have been performed of the flow in a smooth circular pipe of radius $R$ and axial length $10\pi R$ at friction Reynolds numbers up to $Re_\tau=5200$. Various turbulence statistics are…
Intrasaccular flow disruptors treat cerebral aneurysms by diverting the blood flow from the aneurysm sac. Residual flow into the sac after the intervention is a failure that could be due to the use of an undersized device, or to vascular…
In this paper, investigations are conducted using Reynolds-averaged Navier-Stokes (RANS) turbulence models to investigate the importance of turbulence modelling for nasal inspiration at a constant flow rate of 250 ml/s. Four different,…
Objective: To develop and interpret a supervised variational autoencoder (VAE) model for classifying cardiotocography (CTG) signals based on pregnancy outcomes, addressing interpretability limits of current deep learning approaches.…
Mathematical models are widely recognized as a valuable tool for cardiovascular diagnosis and the study of circulatory diseases, especially to obtain data that require otherwise invasive measurements. To correctly simulate body…
Aortic valve stenosis (AVS) presents challenges in asymptomatic detection, resulting in delayed intervention. This study aims to understand how AVS affects pulse wave (PW) morphology. A PW database of 16,038 virtual subjects aged 50 to 75…
It has previously been shown that by increasing the Reynolds number across a channel by spatially varying the viscosity does not cause an immediate change in the size of turbulent structures and a delay is in fact observed in both wall…
Nasal breathing difficulties (NBD) are widespread and difficult to diagnose; the failure rate of their surgical corrections is high. Computational Fluid Dynamics (CFD) enables diagnosis of NBD and surgery planning, by comparing a…
Large neck vessels (carotid artery and internal jugular vein, IJV) offer a unique opportunity to monitor hemodynamics non-invasively by optical means. The primary shortcoming of past work has been the focus on healthy volunteers in normal…
In the presented study, a numerical model which predicts the flow-induced collapse within the pharyngeal airway is validated using in vitro measurements. Theoretical simplifications were considered to limit the computation time. Systematic…
Airflow signal encodes rich information about respiratory system. While the gold standard for measuring airflow is to use a spirometer with an occlusive seal, this is not practical for ambulatory monitoring of patients. Advances in sensor…
Abdominal aortic aneurysm (AAA) is a life-threatening condition characterized by the progressive dilation of the aorta, which can lead to rupture if undetected or untreated. Stress-based rupture risk estimation using computational…
Accurate 3D representations of cardiac structures allow quantitative analysis of anatomy and function. In this work, we propose a method for reconstructing complete 3D cardiac shapes from segmentations of sparse planes in CT angiography…
This paper presents a new method for modeling the mechanics of the aortic valve, and simulates its interaction with blood. As much as possible, the model construction is based on first principles, but such that the model is consistent with…
Cardiac arrhythmogenesis is governed by complex electromechanical interactions that are not directly observable in vivo, motivating the development of non-invasive computational approaches for reconstructing three-dimensional activation…
The choice of lung protective ventilation settings for mechanical ventilation has a considerable impact on patient outcome, yet identifying optimal ventilatory settings for individual patients remains highly challenging due to the inherent…
The significant rates of post-operative arterial thrombus formation following the sutured anastomosis (surgical connection) of vessels in microvascular reconstruction has kindled the development of engineered solutions such as the UNILINK…