Related papers: MixRx: Predicting Drug Combination Interactions wi…

Large language models (LLMs) have demonstrated outstanding performance in natural language processing tasks. However, in the field of recommender systems, due to the inherent structural discrepancy between user behavior data and natural…

Drug-drug interaction event (DDIE) prediction is crucial for preventing adverse reactions and ensuring optimal therapeutic outcomes. However, existing methods often face challenges with imbalanced datasets, complex interaction mechanisms,…

Achieving balanced alignment of large language models (LLMs) in terms of Helpfulness, Honesty, and Harmlessness (3H optimization) constitutes a cornerstone of responsible AI. Existing methods like data mixture strategies face limitations,…

The performance of finetuned large language models (LLMs) hinges critically on the composition of the training mixture. However, selecting an optimal blend of task datasets remains a largely manual, heuristic driven process, with…

In recent years, numerous machine learning models which attempt to solve polypharmacy side effect identification, drug-drug interaction prediction and combination therapy design tasks have been proposed. Here, we present a unified…

To acquire instruction-following capabilities, large language models (LLMs) undergo instruction tuning, where they are trained on instruction-response pairs using next-token prediction (NTP). Efforts to improve instruction tuning often…

Large language models (LLMs) are increasingly used in statistical research and applications. However,they are also notorious for unreliable or biased information. Here, we explore whether LLMs can be used to improve the precision of…

Large Language Models (LLMs) have the potential to accelerate small molecule drug design due to their ability to reason about information from diverse sources and formats. However, their practical utility remains unclear due to the lack of…

Large Language Models (LLMs) exhibit potential artificial generic intelligence recently, however, their usage is costly with high response latency. Given mixed LLMs with their own strengths and weaknesses, LLM routing aims to identify the…

Multimodal recommender systems (MRS) integrate heterogeneous user and item data, such as text, images, and structured information, to enhance recommendation performance. The emergence of large language models (LLMs) introduces new…

Large Language Models (LLMs) with their strong task-handling capabilities have shown remarkable advancements across a spectrum of fields, moving beyond natural language understanding. However, their proficiency within the chemistry domain…

We study the limitations of Large Language Models (LLMs) for the task of response generation in human-machine dialogue. Several techniques have been proposed in the literature for different dialogue types (e.g., Open-Domain). However, the…

Large language models (LLMs) are increasingly integrated into high-stakes decision-making. Inspired by the theory of \emph{inattentional blindness} in human cognition, we investigate whether LLMs, trained on human-preferred corpora that…

Fine-tuning of Large Language Models (LLMs) has become the default practice for improving model performance on a given task. However, performance improvement comes at the cost of training on vast amounts of annotated data which could be…

Purpose: Large language models (LLMs) have proven performance for certain diagnostic tasks, however limited studies have evaluated their consistency in recommending appropriate medication regimens for a given diagnosis. Medication…

Most of the existing medication recommendation models are predicted with only structured data such as medical codes, with the remaining other large amount of unstructured or semi-structured data underutilization. To increase the utilization…

We present Large Language Model for Mixed Reality (LLMR), a framework for the real-time creation and modification of interactive Mixed Reality experiences using LLMs. LLMR leverages novel strategies to tackle difficult cases where ideal…

Our study explores how well the state-of-the-art Large Language Models (LLMs), like GPT-4 and Mistral, can assess the quality of scientific summaries or, more fittingly, scientific syntheses, comparing their evaluations to those of human…

In this paper, we introduce a method for fine-tuning Large Language Models (LLMs), inspired by Multi-Task learning in a federated manner. Our approach leverages the structure of each client's model and enables a learning scheme that…

In this paper, we investigate the presence of additive bias in Large Language Models (LLMs), drawing a parallel to the cognitive bias observed in humans where individuals tend to favor additive over subtractive changes. Using a series of…