Related papers: MixRx: Predicting Drug Combination Interactions wi…

Large language models (LLMs) such as ChatGPT, Gemini, LlaMa, and Claude are trained on massive quantities of text parsed from the internet and have shown a remarkable ability to respond to complex prompts in a manner often indistinguishable…

We present an advanced approach to medical question-answering (QA) services, using fine-tuned Large Language Models (LLMs) to improve the accuracy and reliability of healthcare information. Our study focuses on optimizing models like…

Data selection for finetuning Large Language Models (LLMs) can be framed as a budget-constrained optimization problem: maximizing a model's downstream performance under a strict training data budget. Solving this problem is generally…

For large libraries of small molecules, exhaustive combinatorial chemical screens become infeasible to perform when considering a range of disease models, assay conditions, and dose ranges. Deep learning models have achieved state of the…

Predicting human behavior in shared environments is crucial for safe and efficient human-robot interaction. Traditional data-driven methods to that end are pre-trained on domain-specific datasets, activity types, and prediction horizons. In…

Large language models (LLMs) that are tuned with instructions have demonstrated remarkable capabilities in various tasks and languages. However, their ability to generalize to underrepresented languages is limited due to the scarcity of…

Large Language Models (LLMs) excel in diverse tasks but often underperform in specialized fields due to limited domain-specific or proprietary corpus. Continual pre-training (CPT) enhances LLM capabilities by imbuing new domain-specific or…

This paper explores the integration of Large Language Models (LLMs) into Automatic Speech Recognition (ASR) systems to improve transcription accuracy. The increasing sophistication of LLMs, with their in-context learning capabilities and…

With LLMs shifting their role from statistical modeling of language to serving as general-purpose AI agents, how should LLM evaluations change? Arguably, a key ability of an AI agent is to flexibly combine, as needed, the basic skills it…

Large language models (LLMs) are typically fine-tuned on diverse and extensive datasets sourced from various origins to develop a comprehensive range of skills, such as writing, reasoning, chatting, coding, and more. Each skill has unique…

Large Language Models (LLMs) have recently demonstrated impressive capabilities across various real-world applications. However, due to the current text-in-text-out paradigm, it remains challenging for LLMs to handle dynamic and complex…

Large language models (LLMs) achieve strong performance in long-horizon decision-making tasks through multi-step interaction and reasoning at test time. While practitioners commonly believe a higher task success rate necessitates the use of…

While integrating tools like Code Interpreter and Search has significantly enhanced Large Language Model (LLM) reasoning in models like ChatGPT Agent and Gemini-Pro, practical guidance on optimal tool use is lacking. The core challenge is…

Physicians considering clinical trials for their patients are met with the laborious process of checking many text based eligibility criteria. Large Language Models (LLMs) have shown to perform well for clinical information extraction and…

Material selection is a crucial step in conceptual design due to its significant impact on the functionality, aesthetics, manufacturability, and sustainability impact of the final product. This study investigates the use of Large Language…

Recent studies have found that summaries generated by large language models (LLMs) are favored by human annotators over the original reference summaries in commonly used summarization datasets. Therefore, we study an LLM-as-reference…

This study investigates the adoption of open-access, locally deployable causal large language models (LLMs) for travel mode choice prediction and introduces LiTransMC, the first fine-tuned causal LLM developed for this task. We…

Fine-tuning pretrained language models (PLMs) on downstream tasks has become common practice in natural language processing. However, most of the PLMs are vulnerable, e.g., they are brittle under adversarial attacks or imbalanced data,…

Drug repurposing is often framed as a candidate identification task, but existing approaches provide limited guidance for distinguishing biologically plausible candidates from historically well-connected ones. Here we introduce DrugKLM, a…

Adverse drug interactions are largely preventable causes of medical accidents, which frequently result in physician and emergency room encounters. The detection of drug interactions in a lab, prior to a drug's use in medical practice, is…