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Accurate segmentation of carotid artery structures in histopathological images is vital for cardiovascular disease research. This study systematically evaluates ten deep learning segmentation models including classical architectures, modern…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Phongsakon Mark Konrad , Andrei-Alexandru Popa , Yaser Sabzehmeidani , Liang Zhong , Madhulika Tripathy , Andrei Constantinescu , Elisa A. Liehn , Serkan Ayvaz

The density of mitotic figures within tumor tissue is known to be highly correlated with tumor proliferation and thus is an important marker in tumor grading. Recognition of mitotic figures by pathologists is known to be subject to a strong…

Segmentation is essential for medical image analysis tasks such as intervention planning, therapy guidance, diagnosis, treatment decisions. Deep learning is becoming increasingly prominent for segmentation, where the lack of annotations,…

Computer Vision and Pattern Recognition · Computer Science 2019-03-19 Firat Ozdemir , Zixuan Peng , Christine Tanner , Philipp Fuernstahl , Orcun Goksel

Data augmentation plays a pivotal role in enhancing and diversifying training data. Nonetheless, consistently improving model performance in varied learning scenarios, especially those with inherent data biases, remains challenging. To…

Machine Learning · Computer Science 2024-06-04 Xiaoling Zhou , Wei Ye , Zhemg Lee , Rui Xie , Shikun Zhang

In histopathology, tissue samples are often larger than a standard microscope slide, making stitching of multiple fragments necessary to process entire structures such as tumors. Automated stitching is a prerequisite for scaling analysis,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Stefan Brandstätter , Maximilian Köller , Philipp Seeböck , Alissa Blessing , Felicitas Oberndorfer , Svitlana Pochepnia , Helmut Prosch , Georg Langs

Generative modelling and synthetic data can be a surrogate for real medical imaging datasets, whose scarcity and difficulty to share can be a nuisance when delivering accurate deep learning models for healthcare applications. In recent…

Image and Video Processing · Electrical Eng. & Systems 2024-02-27 Virginia Fernandez , Walter Hugo Lopez Pinaya , Pedro Borges , Mark S. Graham , Tom Vercauteren , M. Jorge Cardoso

In biomedical imaging, deep learning-based methods are state-of-the-art for every modality (virtual slides, MRI, etc.) In histopathology, these methods can be used to detect certain biomarkers or classify lesions. However, such techniques…

Computer Vision and Pattern Recognition · Computer Science 2023-03-10 Adrien Nivaggioli , Nicolas Pozin , Rémy Peyret , Stéphane Sockeel , Marie Sockeel , Nicolas Nerrienet , Marceau Clavel , Clara Simmat , Catherine Miquel

Downsampling or under-sampling is a technique that is utilized in the context of large and highly imbalanced classification models. We study optimal downsampling for imbalanced classification using generalized linear models (GLMs). We…

Machine Learning · Statistics 2025-05-20 Yan Chen , Jose Blanchet , Krzysztof Dembczynski , Laura Fee Nern , Aaron Flores

This dissertation explores the impact of bias in deep neural networks and presents methods for reducing its influence on model performance. The first part begins by categorizing and describing potential sources of bias and errors in data…

Machine Learning · Computer Science 2023-08-21 Agnieszka Mikołajczyk-Bareła

Background: Clinical prediction models are increasingly used to inform healthcare decisions, but determining the minimum sample size for their development remains a critical and unresolved challenge. Inadequate sample sizes can lead to…

Machine Learning · Computer Science 2026-03-02 Diana Shamsutdinova , Felix Zimmer , Oyebayo Ridwan Olaniran , Sarah Markham , Daniel Stahl , Gordon Forbes , Ewan Carr

Bounding and predicting the generalization gap of overparameterized neural networks remains a central open problem in theoretical machine learning. There is a recent and growing body of literature that proposes the framework of fractals to…

Machine Learning · Computer Science 2024-11-04 Charlie B. Tan , Inés García-Redondo , Qiquan Wang , Michael M. Bronstein , Anthea Monod

Topological correctness, i.e., the preservation of structural integrity and specific characteristics of shape, is a fundamental requirement for medical imaging tasks, such as neuron or vessel segmentation. Despite the recent surge in…

Computer Vision and Pattern Recognition · Computer Science 2024-12-20 Alexander H. Berger , Laurin Lux , Alexander Weers , Martin Menten , Daniel Rueckert , Johannes C. Paetzold

Medical image segmentation is critical for clinical diagnosis, treatment planning, and monitoring, yet segmentation models often struggle with uncertainties stemming from occlusions, ambiguous boundaries, and variations in imaging devices.…

Computer Vision and Pattern Recognition · Computer Science 2026-01-05 Xiao Ma , Yuhui Tao , Zetian Zhang , Yuhan Zhang , Xi Wang , Sheng Zhang , Zexuan Ji , Yizhe Zhang , Qiang Chen , Guang Yang

In computer vision, it is standard practice to draw a single sample from the data augmentation procedure for each unique image in the mini-batch. However recent work has suggested drawing multiple samples can achieve higher test accuracies.…

Machine Learning · Computer Science 2022-02-25 Stanislav Fort , Andrew Brock , Razvan Pascanu , Soham De , Samuel L. Smith

Recent advancements in large-scale pretraining in natural language processing have enabled pretrained vision-language models such as CLIP to effectively align images and text, significantly improving performance in zero-shot image…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Thanh Hieu Cao , Trung Khang Tran , Gia Thinh Pham , Tuong Nghiem Diep , Thanh Binh Nguyen

Augmentation for dense prediction typically relies on either sample mixing or generative synthesis. Mixing improves robustness but misaligned masks yield soft label ambiguity. Diffusion synthesis increases apparent diversity but, when…

Computer Vision and Pattern Recognition · Computer Science 2025-11-06 Pengyu Jie , Wanquan Liu , Rui He , Yihui Wen , Deyu Meng , Chenqiang Gao

Text-to-image flow matching transformers degrade sharply in long-tail settings: tail-class outputs collapse in fidelity and diversity, limiting their value as synthetic augmentation for rare conditions. We trace this to low head-versus-tail…

Computer Vision and Pattern Recognition · Computer Science 2026-05-13 Felix Nützel , Mischa Dombrowski , Bernhard Kainz

While medical image segmentation is an important task for computer aided diagnosis, the high expertise requirement for pixelwise manual annotations makes it a challenging and time consuming task. Since conventional data augmentations do not…

Image and Video Processing · Electrical Eng. & Systems 2021-06-21 Dwarikanath Mahapatra , Ankur Singh

Leveraging the vision foundation models has emerged as a mainstream paradigm that improves the performance of image feature matching. However, previous works have ignored the misalignment when introducing the foundation models into feature…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 Yuhan Liu , Jingwen Fu , Yang Wu , Kangyi Wu , Pengna Li , Jiayi Wu , Sanping Zhou , Jingmin Xin

Recent years have seen considerable progress in the continual training of deep neural networks, predominantly thanks to approaches that add replay or regularization terms to the loss function to approximate the joint loss over all tasks so…

Machine Learning · Computer Science 2024-11-01 Timm Hess , Tinne Tuytelaars , Gido M. van de Ven
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