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A valuable step in the modeling of multiscale dynamical systems in fields such as computational chemistry, biology, materials science and more, is the representative sampling of the phase space over long timescales of interest; this task is…

Machine Learning · Computer Science 2023-12-29 Ellis R. Crabtree , Juan M. Bello-Rivas , Ioannis G. Kevrekidis

Digital pathology has significantly advanced disease detection and pathologist efficiency through the analysis of gigapixel whole-slide images (WSI). In this process, WSIs are first divided into patches, for which a feature extractor model…

Computer Vision and Pattern Recognition · Computer Science 2024-08-05 Gustav Bredell , Marcel Fischer , Przemyslaw Szostak , Samaneh Abbasi-Sureshjani , Alvaro Gomariz

Data augmentation is an effective and universal technique for improving generalization performance of deep neural networks. It could enrich diversity of training samples that is essential in medical image segmentation tasks because 1) the…

Image and Video Processing · Electrical Eng. & Systems 2020-12-29 Ju Xu , Mengzhang Li , Zhanxing Zhu

Surgical segmentation is pivotal for scene understanding yet remains hindered by annotation scarcity and semantic inconsistency across diverse procedures. Existing approaches typically fine-tune natural foundation models (e.g., SAM) with…

Computer Vision and Pattern Recognition · Computer Science 2025-12-10 Qing Xu , Kun Yuan , Yuxiang Luo , Yuhao Zhai , Wenting Duan , Nassir Navab , Zhen Chen

Visual Foundation Models (VFMs) such as the Segment Anything Model (SAM) have significantly advanced broad use of image segmentation. However, SAM and its variants necessitate substantial manual effort for prompt generation and additional…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Minjae Lee , Sungwoo Hur , Soojin Hwang , Won Hwa Kim

Automated segmentation is a fundamental medical image analysis task, which enjoys significant advances due to the advent of deep learning. While foundation models have been useful in natural language processing and some vision tasks for…

Computer Vision and Pattern Recognition · Computer Science 2025-05-12 Hanxue Gu , Haoyu Dong , Jichen Yang , Maciej A. Mazurowski

Single-source domain generalization (SDG) in medical image segmentation is a challenging yet essential task as domain shifts are quite common among clinical image datasets. Previous attempts most conduct global-only/random augmentation.…

Computer Vision and Pattern Recognition · Computer Science 2022-11-29 Zixian Su , Kai Yao , Xi Yang , Qiufeng Wang , Jie Sun , Kaizhu Huang

Pathology foundation models (PFMs) have advanced rapidly in recent years and support training classifiers for a range of histopathology tasks. However, their robustness across hospitals remains limited: performance often degrades when…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Ben Vardi , Dana Schonberger , Yuval Friedmann , Zohar Yakhini , Iris Barshack , Alexander Loebel , Ariel Shamir

Breast cancer remains a critical global health challenge, necessitating early and accurate detection for effective treatment. This paper introduces a methodology that combines automated image augmentation selection (RandAugment) with search…

Image and Video Processing · Electrical Eng. & Systems 2023-11-21 Leon Hamnett , Mary Adewunmi , Modinat Abayomi , Kayode Raheem , Fahad Ahmed

Capturing the global topology of an image is essential for proposing an accurate segmentation of its domain. However, most of existing segmentation methods do not preserve the initial topology of the given input, which is detrimental for…

Computer Vision and Pattern Recognition · Computer Science 2022-08-19 Minh On Vu Ngoc , Yizi Chen , Nicolas Boutry , Jonathan Fabrizio , Clement Mallet

Robust fine-tuning aims to adapt large foundation models to downstream tasks while preserving their robustness to distribution shifts. Existing methods primarily focus on constraining and projecting current model towards the pre-trained…

Machine Learning · Computer Science 2025-06-24 Chengyue Huang , Junjiao Tian , Brisa Maneechotesuwan , Shivang Chopra , Zsolt Kira

Importance Sampling methods are broadly used to approximate posterior distributions or some of their moments. In its standard approach, samples are drawn from a single proposal distribution and weighted properly. However, since the…

Computation · Statistics 2019-11-05 Víctor Elvira , Luca Martino , David Luengo , Mónica F. Bugallo

In digital pathology, acquiring all-in-focus images is essential to high-quality imaging and high-efficient clinical workflow. Traditional scanners achieve this by scanning at multiple focal planes of varying depths and then merging them,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Jiangdong Cai , Yan Chen , Zhenrong Shen , Haotian Jiang , Honglin Xiong , Kai Xuan , Lichi Zhang , Qian Wang

A central limitation of multiple-acquisition magnetic resonance imaging (MRI) is the degradation in scan efficiency as the number of distinct datasets grows. Sparse recovery techniques can alleviate this limitation via randomly undersampled…

Image and Video Processing · Electrical Eng. & Systems 2017-10-03 L Kerem Senel , Toygan Kilic , Alper Gungor , Emre Kopanoglu , H Emre Guven , Emine U Saritas , Aykut Koc , Tolga Cukur

Computational pathology (CPath) has shown great potential in mining actionable insights from Whole Slide Images (WSIs). Deep Learning (DL) has been at the center of modern CPath, and while it delivers unprecedented performance, it is also…

Quantitative Methods · Quantitative Biology 2025-07-31 Gianluca Carloni , Biagio Brattoli , Seongho Keum , Jongchan Park , Taebum Lee , Chang Ho Ahn , Sergio Pereira

The emergence of foundation models in computational pathology has transformed histopathological image analysis, with whole slide imaging (WSI) diagnosis being a core application. Traditionally, weakly supervised fine-tuning via multiple…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Jiawen Li , Jiali Hu , Qiehe Sun , Renao Yan , Minxi Ouyang , Tian Guan , Anjia Han , Chao He , Yonghong He

Synthesizing medical images while preserving their structural information is crucial in medical research. In such scenarios, the preservation of anatomical content becomes especially important. Although recent advances have been made by…

Image and Video Processing · Electrical Eng. & Systems 2024-11-14 Ziqi Yu , Botao Zhao , Shengjie Zhang , Xiang Chen , Jianfeng Feng , Tingying Peng , Xiao-Yong Zhang

Deep networks are now ubiquitous in large-scale multi-center imaging studies. However, the direct aggregation of images across sites is contraindicated for downstream statistical and deep learning-based image analysis due to inconsistent…

Image and Video Processing · Electrical Eng. & Systems 2021-04-16 Mengwei Ren , Neel Dey , James Fishbaugh , Guido Gerig

Diffusion models have shown impressive performance for generative modelling of images. In this paper, we present a novel semantic segmentation method based on diffusion models. By modifying the training and sampling scheme, we show that…

Computer Vision and Pattern Recognition · Computer Science 2021-12-28 Julia Wolleb , Robin Sandkühler , Florentin Bieder , Philippe Valmaggia , Philippe C. Cattin

Disaggregation regression has become an important tool in spatial disease mapping for making fine-scale predictions of disease risk from aggregated response data. By including high resolution covariate information and modelling the data…

Applications · Statistics 2020-05-08 Rohan Arambepola , Tim C D Lucas , Anita K Nandi , Peter W Gething , Ewan Cameron