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Synapses play a critical role in memory, learning, and cognition. Their main functions include converting pre-synaptic voltage spikes to post-synaptic currents, as well as scaling the input signal. Several brain-inspired architectures have…

Signal Processing · Electrical Eng. & Systems 2022-03-24 Mohammad Javad Mirshojaeian Hosseini , Elisa Donati , Giacomo Indiveri , Robert A. Nawrocki

Nanomechanical computers promise robust, low energy information processing. However, to date, electronics have generally been required to interconnect gates, while no scalable, purely nanomechanical approach to computing has been achieved.…

Quantum computing promises to exploit the laws of quantum mechanics for processing information in ways fundamentally different from today's classical computers, leading to unprecedented efficiency. One-way quantum computation, sometimes…

Invertible logic can operate in one of two modes: 1) a forward mode, in which inputs are presented and a single, correct output is produced, and 2) a reverse mode, in which the output is fixed and the inputs take on values consistent with…

Hardware Architecture · Computer Science 2026-03-31 Sean C. Smithson , Naoya Onizawa , Brett H. Meyer , Warren J. Gross , Takahiro Hanyu

Simulating response properties of molecules is crucial for interpreting experimental spectroscopies and accelerating materials design. However, it remains a long-standing computational challenge for electronic structure methods on classical…

Computation models such as circuits describe sequences of computation steps that are carried out one after the other. In other words, algorithm design is traditionally subject to the restriction imposed by a fixed causal order. We address a…

Quantum Physics · Physics 2017-07-04 Ämin Baumeler , Stefan Wolf

We introduce a general scheme for sequential one-way quantum computation where static systems with long-living quantum coherence (memories) interact with moving systems that may possess very short coherence times. Both the generation of the…

Quantum Physics · Physics 2015-05-27 Augusto J. Roncaglia , Leandro Aolita , Alessandro Ferraro , Antonio Acin

Chemical large language models (LLMs) predominantly rely on explicit Chain-of-Thought (CoT) in natural language to perform complex reasoning. However, chemical reasoning is inherently continuous and structural, and forcing it into discrete…

Current genomic foundation models (GFMs) rely on extensive neural computation to implicitly approximate conserved biological motifs from single-nucleotide inputs. We propose Gengram, a conditional memory module that introduces an explicit…

A programmable optical computer has remained an elusive concept. To construct a practical computing primitive equivalent to an electronic Boolean logic, one should find a nonlinear phenomenon that overcomes weaknesses present in many…

Emerging Technologies · Computer Science 2017-09-26 Tuomo von Lerber , Matti Lassas , Quang Trung Le , Vladimir Lyubopytov , Arkadi Chipouline , Klaus Hofmann , Franko Kueppers

Our computers today, from sophisticated servers to small smartphones, operate based on the same computing model, which requires running a sequence of discrete instructions, specified as an algorithm. This sequential computing paradigm has…

Computational Complexity · Computer Science 2021-12-02 Seyed Mousavi

Unconventional computing devices are increasingly of interest as they can operate in environments hostile to silicon-based electronics, or compute in ways that traditional electronics cannot. Mechanical computers, wherein information…

Emerging Technologies · Computer Science 2023-05-30 Atoosa Parsa , Sven Witthaus , Nidhi Pashine , Corey S. O'Hern , Rebecca Kramer-Bottiglio , Josh Bongard

Robustness to a wide variety of negative factors and the ability to self-repair is an inherent and natural characteristic of all life forms on earth. As opposed to nature, man-made systems are in most cases not inherently robust and a…

Neural and Evolutionary Computing · Computer Science 2016-11-15 Christof Teuscher

DNA sequencing allows for the determination of the genetic code of an organism, and therefore is an indispensable tool that has applications in Medicine, Life Sciences, Evolutionary Biology, Food Sciences and Technology, and Agriculture. In…

Quantum Physics · Physics 2023-04-24 Nouhaila Innan , Muhammad Al-Zafar Khan

One of the outstanding challenges in contemporary science and technology is building a quantum computer that is useful in applications. By starting from an estimate of the algorithm success rate, we can explicitly connect gate fidelity to…

Quantum Physics · Physics 2026-03-20 R. Barends , F. K. Wilhelm

Computational chemistry allows researchers to experiment in sillico: by running a computer simulations of a biological or chemical processes of interest. Molecular dynamics with molecular mechanics model of interactions simulates N-body…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-03-03 Jana Pazúriková

Chemputation reframes synthesis as the programmable execution of reaction code on a universally re-configurable hardware graph. Here we prove that a chemputer equipped with a finite, but extensible, set of reagents, catalysts and process…

Emerging Technologies · Computer Science 2025-07-22 Leroy Cronin , Sebastian Pagel , Abhishek Sharma

Quantum computing leverages the unique properties of qubits and quantum parallelism to solve problems intractable for classical systems, offering unparalleled computational potential. However, the optimization of quantum circuits remains…

Memristors have been suggested as a novel route to neuromorphic computing based on the similarity between neurons (synapses and ion pumps) and memristors. The D.C. action of the memristor is a current spike, which we think will be fruitful…

Emerging Technologies · Computer Science 2014-02-18 Ella Gale , Ben de Lacy Costello , Andrew Adamatzky

With the advent of multi-core processors and their fast expansion, it is quite clear that {\em parallel computing} is now a genuine requirement in Computer Science and Engineering (and related) curriculum. In addition to the pervasiveness…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-02-13 Claude Tadonki
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