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We apply logic-based machine learning techniques to facilitate cellular engineering and drive biological discovery, based on comprehensive databases of metabolic processes called genome-scale metabolic network models (GEMs). Predicted host…

Artificial Intelligence · Computer Science 2024-11-14 Lun Ai , Stephen H. Muggleton , Shi-shun Liang , Geoff S. Baldwin

In order to realize a Quantum CPU some schemes for executing fundamental mathematical tasks are needed. In this paper we present some quantum circuits which, using elementary arithmetic operations, allow an approximated calculation of…

Quantum Physics · Physics 2007-05-23 G. Florio , D. Picca

This chapter presents a quantum computing-based approach to study and harness neuronal correlates of mental activity for the development of Brain-Computer Interface (BCI) systems. It introduces the notion of a logic of the mind, where…

Emerging Technologies · Computer Science 2021-01-19 Eduardo Reck Miranda

Memcomputing logic gates generalize the traditional Boolean logic gates for operation in the reverse direction. According to the literature, this functionality enables the efficient solution of computationally-intensive problems including…

Emerging Technologies · Computer Science 2024-02-02 Y. V. Pershin

Enzyme is the major workhorse to carry out the diverse cellular functions. It catalyzes the biological reactions with a high specificity, with its topology playing a crucial role. For ecologically safe production of numerous bioproducts…

Biomolecules · Quantitative Biology 2021-06-04 Prabha Sankara Narayanan , Ashish Runthala

In this study, we propose a novel computing paradigm "Bit Stream Computing" that is constructed on the logic used in stochastic computing, but does not necessarily employ randomly or Binomially distributed bit streams as stochastic…

Emerging Technologies · Computer Science 2019-04-30 Ensar Vahapoglu , Mustafa Altun

We show how a quantum computer can be employed to elucidate reaction mechanisms in complex chemical systems, using the open problem of biological nitrogen fixation in nitrogenase as an example. We discuss how quantum computers can augment…

Quantum Physics · Physics 2017-08-14 Markus Reiher , Nathan Wiebe , Krysta M Svore , Dave Wecker , Matthias Troyer

Enzymes are nano-scale machines that have evolved to drive chemical reactions out of equilibrium in the right place at the right time. Given the complexity and specificity of enzymatic function, bottom-up design of enzymes presents a…

Soft Condensed Matter · Physics 2025-05-28 Michalis Chatzittofi , Jaime Agudo-Canalejo , Ramin Golestanian

In present day technology, storing and processing of information occur on physically distinct regions of space. Not only does this result in space limitations; it also translates into unwanted delays in retrieving and processing of relevant…

Emerging Technologies · Computer Science 2013-04-09 M. Di Ventra , Y. V. Pershin

Following the success of Moore's predictions, we are approaching a limit in the miniaturization of semiconductors for computing materials. This has led to the exploration of various research paths to develop alternative computing paradigms,…

Quantum Physics · Physics 2026-05-20 Dawit Hiluf Hailu

Rule-based reasoning is an essential part of human intelligence prominently formalized in artificial intelligence research via logic programs. Describing complex objects as the composition of elementary ones is a common strategy in computer…

Artificial Intelligence · Computer Science 2023-12-15 Christian Antic

Molecular biology explains function of molecules by their geometrical and electronical structures that are mainly determined by utilization of quantum effects in chemistry. However, further quantum effects are not thought to play any…

Quantum Physics · Physics 2011-12-30 Onur Pusuluk , Cemsinan Deliduman

We now need more than ever to make genome analysis more intelligent. We need to read, analyze, and interpret our genomes not only quickly, but also accurately and efficiently enough to scale the analysis to population level. There currently…

Advancements in artificial intelligence for molecular science are necessitating a paradigm shift from purely data-driven predictions to knowledge-guided computational reasoning. Existing molecular models are predominantly proprietary,…

Machine Learning · Computer Science 2026-03-16 Pengfei Liu , Shuang Ge , Jun Tao , Zhixiang Ren

Practical challenges in simulating quantum systems on classical computers have been widely recognized in the quantum physics and quantum chemistry communities over the past century. Although many approximation methods have been introduced,…

We discuss efficient quantum logic circuits which perform two tasks: (i) implementing generic quantum computations and (ii) initializing quantum registers. In contrast to conventional computing, the latter task is nontrivial because the…

Quantum Physics · Physics 2007-05-23 Vivek V. Shende , Stephen S. Bullock , Igor L. Markov

Chronic diseases can greatly benefit from bioelectronic medicine approaches. Neuromorphic electronic circuits present ideal characteristics for the development of brain-inspired low-power implantable processing systems that can be…

Emerging Technologies · Computer Science 2021-02-22 Elisa Donati , Renate Krause , Giacomo Indiveri

The conductor-like polarization model (C-PCM) with switching/Gaussian smooth discretization is a widely used implicit solvation model in chemical simulations. However, its application in quantum mechanical calculations of large-scale…

Chemical Physics · Physics 2015-07-03 Fang Liu , Nathan Luehr , Heather J. Kulik , Todd J. Martínez

Experiments with superconducting quantum processors have successfully demonstrated the basic functions needed for quantum computation and evidence of utility, albeit without a sizable array of error-corrected qubits. The realization of the…

Geometric phase, associated with holonomy transformation in quantum state space, is an important quantum-mechanical effect. Besides fundamental interest, this effect has practical applications, among which geometric quantum computation is a…

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