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Quantitative MRI enables direct quantification of contrast agent concentrations in contrast-enhanced scans. However, the lengthy scan times required by conventional methods are inadequate for tracking contrast agent transport dynamically in…

Deep learning has emerged as a promising approach for learning the nonlinear mapping between diffusion-weighted MR images and tissue parameters, which enables automatic and deep understanding of the brain microstructures. However, the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-21 Wenxin Fan , Jian Cheng , Qiyuan Tian , Ruoyou Wu , Juan Zou , Zan Chen , Shanshan Wang

Purpose: The clinical feasibility and translation of many advanced quantitative MRI (qMRI) techniques are inhibited by their restriction to 'research mode', due to resource-intensive, offline parameter estimation. This work aimed to achieve…

Purpose: To develop a self-supervised scan-specific deep learning framework for reconstructing accelerated multiparametric quantitative MRI (qMRI). Methods: We propose REFINE-MORE (REference-Free Implicit NEural representation with MOdel…

Medical Physics · Physics 2025-08-05 Ruimin Feng , Albert Jang , Xingxin He , Fang Liu

Recent advances in generative models for medical imaging have shown promise in representing multiple modalities. However, the variability in modality availability across datasets limits the general applicability of the synthetic data they…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Sven Lüpke , Yousef Yeganeh , Ehsan Adeli , Nassir Navab , Azade Farshad

Water diffusion gives rise to micron-scale sensitivity of diffusion MRI (dMRI) to cellular-level tissue structure. Precision medicine and quantitative imaging depend on uncovering the information content of dMRI and establishing its…

Medical Physics · Physics 2026-02-03 Santiago Coelho , Jenny Chen , Filip Szczepankiewicz , Els Fieremans , Dmitry S. Novikov

Quantitative phase imaging (QPI) quantifies the sample-specific optical-phase-delay enabling objective studies of optically-transparent specimens such as biological samples, but lacks chemical sensitivity limiting its application to…

Optics · Physics 2019-09-04 Miu Tamamitsu , Keiichiro Toda , Ryoichi Horisaki , Takuro Ideguchi

To our knowledge, all deep computer-aided detection and diagnosis (CAD) systems for prostate cancer (PCa) detection consider bi-parametric magnetic resonance imaging (bp-MRI) only, including T2w and ADC sequences while excluding the 4D…

Image and Video Processing · Electrical Eng. & Systems 2022-07-08 Audrey Duran , Gaspard Dussert , Carole Lartizien

In MR fingerprinting (MRF) reconstruction, measured data is pattern-matched to simulated signals to extract quantitative tissue parameters. A critical drawback to this approach is the exponentially increasing compute time for mapping of…

Medical Physics · Physics 2024-07-17 Victoria Y. Yu , Kathryn R. Tringale , Ricardo Otazo , Ouri Cohen

With applications ranging from metabolomics to histopathology, quantitative phase microscopy (QPM) is a powerful label-free imaging modality. Despite significant advances in fast multiplexed imaging sensors and deep-learning-based inverse…

Diffusion models have received wide attention in generation tasks. However, the expensive computation cost prevents the application of diffusion models in resource-constrained scenarios. Quantization emerges as a practical solution that…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Weilun Feng , Haotong Qin , Chuanguang Yang , Zhulin An , Libo Huang , Boyu Diao , Fei Wang , Renshuai Tao , Yongjun Xu , Michele Magno

A low-cost device for registration-free quantitative phase microscopy (QPM) based on the transport of intensity equation (TIE) of cells in continuous flow is presented. The method uses acoustic focusing to align cells into a single plane…

Latent diffusion models (LDMs) have recently achieved strong performance in 3D medical image synthesis. However, modalities like cine cardiac MRI (CMR), representing a temporally synchronized 3D volume across the cardiac cycle, add an…

Purpose: To develop and evaluate a new pulse sequence for highly accelerated distortion-free diffusion MRI (dMRI) by inserting additional echoes without prolonging TR, when generalized slice dithered enhanced resolution (gSlider)…

Despite significant progress in generative modelling, existing diffusion models often struggle to produce anatomically precise female pelvic images, limiting their application in gynaecological imaging, where data scarcity and patient…

Image and Video Processing · Electrical Eng. & Systems 2025-08-26 Johanna P. Müller , Anika Knupfer , Pedro Blöss , Edoardo Berardi Vittur , Bernhard Kainz , Jana Hutter

Expansion of diffusion MRI (dMRI) both into the realm of strong gradients, and into accessible imaging with portable low-field devices, brings about the challenge of gradient nonlinearities. Spatial variations of the diffusion gradients…

Quantitative magnetic resonance imaging (qMRI) allows images to be compared across sites and time points, which is particularly important for assessing long-term conditions or for longitudinal studies. The multiparametric mapping (MPM)…

Signal Processing · Electrical Eng. & Systems 2024-10-24 Klara Baś , Christian Lambert , John Ashburner

We introduce a novel state-space architecture for diffusion models, effectively harnessing spatial and frequency information to enhance the inductive bias towards local features in input images for image generation tasks. While state-space…

Computer Vision and Pattern Recognition · Computer Science 2025-04-14 Hao Phung , Quan Dao , Trung Dao , Hoang Phan , Dimitris Metaxas , Anh Tran

Magnetic Resonance (MR) image reconstruction from under-sampled acquisition promises faster scanning time. To this end, current State-of-The-Art (SoTA) approaches leverage deep neural networks and supervised training to learn a recovery…

Image and Video Processing · Electrical Eng. & Systems 2022-03-14 Cheng Peng , Pengfei Guo , S. Kevin Zhou , Vishal Patel , Rama Chellappa

Diffusion tensor imaging (DTI) is a popular magnetic resonance imaging technique used to characterize microstructural changes in the brain. DTI studies quantify the diffusion of water molecules in a voxel using an estimated 3x3 symmetric…

Methodology · Statistics 2021-03-30 Zhou Lan , Brian J. Reich , Dipankar Bandyopadhyay