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Purpose: To achieve automatic hyperparameter estimation for the joint recovery of quantitative MR images, we propose a Bayesian formulation of the reconstruction problem that incorporates the signal model. Additionally, we investigate the…

Image and Video Processing · Electrical Eng. & Systems 2023-09-12 Shuai Huang , James J. Lah , Jason W. Allen , Deqiang Qiu

Quantification of tissue parameters using MRI is emerging as a powerful tool in clinical diagnosis and research studies. The need for multiple long scans with different acquisition parameters prohibits quantitative MRI from reaching…

Quantitative Methods · Quantitative Biology 2024-08-07 Amir Heydari , Abbas Ahmadi , Tae Hyung Kim , Berkin Bilgic

As a label-free imaging technique, quantitative phase imaging (QPI) provides optical path length information of transparent specimens for various applications in biology, materials science, and engineering. Multispectral QPI measures…

Optics · Physics 2023-08-29 Che-Yung Shen , Jingxi Li , Deniz Mengu , Aydogan Ozcan

The purpose of this study is to present and compare three denoising diffusion probabilistic models (DDPMs) that generate 3D $T_1$-weighted MRI human brain images. Three DDPMs were trained using 80,675 image volumes from 42,406 subjects…

Image and Video Processing · Electrical Eng. & Systems 2025-11-03 Samuel W. Remedios , Aaron Carass , Jerry L. Prince , Blake E. Dewey

Magnetic resonance imaging (MRI) offers superior soft tissue contrast and is widely used in biomedicine. However, conventional MRI is not quantitative, which presents a bottleneck in image analysis and digital healthcare. Typically,…

Diffusional kurtosis imaging (DKI) is a methodology for measuring the extent of non-Gaussian diffusion in biological tissue, which has shown great promise in clinical diagnosis, treatment planning and monitoring of many neurological…

Image and Video Processing · Electrical Eng. & Systems 2024-04-29 Megan E. Farquhar , Qianqian Yang , Viktor Vegh

MRI synthesis promises to mitigate the challenge of missing MRI modality in clinical practice. Diffusion model has emerged as an effective technique for image synthesis by modelling complex and variable data distributions. However, most…

Image and Video Processing · Electrical Eng. & Systems 2023-03-27 Lan Jiang , Ye Mao , Xi Chen , Xiangfeng Wang , Chao Li

The quality of fetal MRI is significantly affected by unpredictable and substantial fetal motion, leading to the introduction of artifacts even when fast acquisition sequences are employed. The development of 3D real-time fetal pose…

Image and Video Processing · Electrical Eng. & Systems 2024-04-02 Molin Zhang , Polina Golland , Patricia Ellen Grant , Elfar Adalsteinsson

Diffusion models have become the most popular approach for high-quality image generation, but their high computational cost still remains a significant challenge. To address this problem, we propose U-Shape Mamba (USM), a novel diffusion…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Alex Ergasti , Filippo Botti , Tomaso Fontanini , Claudio Ferrari , Massimo Bertozzi , Andrea Prati

High-resolution highway traffic state information is essential for Intelligent Transportation Systems, but typical traffic data acquired from loop detectors and probe vehicles are often too sparse and noisy to capture the detailed dynamics…

Machine Learning · Computer Science 2025-12-09 Lindong Liu , Zhixiong Jin , Seongjin Choi

Diffusion models have achieved great success in image synthesis through iterative noise estimation using deep neural networks. However, the slow inference, high memory consumption, and computation intensity of the noise estimation model…

Computer Vision and Pattern Recognition · Computer Science 2023-06-09 Xiuyu Li , Yijiang Liu , Long Lian , Huanrui Yang , Zhen Dong , Daniel Kang , Shanghang Zhang , Kurt Keutzer

Quantitative susceptibility mapping (QSM) is an MRI phase-based post-processing method that quantifies tissue magnetic susceptibility distributions. However, QSM acquisitions are relatively slow, even with parallel imaging. Incoherent…

Image and Video Processing · Electrical Eng. & Systems 2021-07-20 Yang Gao , Martijn Cloos , Feng Liu , Stuart Crozier , G. Bruce Pike , Hongfu Sun

Diffusion models have demonstrated remarkable capabilities in image synthesis and related generative tasks. Nevertheless, their practicality for real-world applications is constrained by substantial computational costs and latency issues.…

Computer Vision and Pattern Recognition · Computer Science 2024-04-16 Yefei He , Jing Liu , Weijia Wu , Hong Zhou , Bohan Zhuang

Purpose: This study aims to develop a high-resolution whole-brain multi-parametric quantitative MRI approach for simultaneous mapping of myelin-water fraction (MWF), T1, T2, and proton-density (PD), all within a clinically feasible scan…

This paper proposes a novel self-supervised learning method, RELAX-MORE, for quantitative MRI (qMRI) reconstruction. The proposed method uses an optimization algorithm to unroll a model-based qMRI reconstruction into a deep learning…

Biological Physics · Physics 2023-07-26 Wanyu Bian , Albert Jang , Fang Liu

Diffusion magnetic resonance imaging (dMRI) is a crucial non-invasive technique for exploring the microstructure of the living human brain. Traditional hand-crafted and model-based tissue microstructure reconstruction methods often require…

Image and Video Processing · Electrical Eng. & Systems 2025-02-26 Xinrui Ma , Jian Cheng , Wenxin Fan , Ruoyou Wu , Yongquan Ye , Shanshan Wang

Purpose: For quantitative susceptibility mapping (QSM), the lack of ground-truth in clinical settings makes it challenging to determine suitable parameters for the dipole inversion. We propose a probabilistic Bayesian approach for QSM with…

Image and Video Processing · Electrical Eng. & Systems 2023-06-01 Shuai Huang , James J. Lah , Jason W. Allen , Deqiang Qiu

Motivation: Conventional echo planar imaging(EPI) based functional MRI(fMRI) uses the BOLD contrast to map activity changes in human brains. Introducing an efficient ZTE sequence for functional brain mapping can help address limitations of…

Medical Physics · Physics 2025-10-28 Ali Caglar Ozen , Shuai Liu , Serhat Ilbey , Michael Bock , Uzay Emir , Yen-Yu Ian Shih

Diffusion MRI is commonly performed using echo-planar imaging (EPI) due to its rapid acquisition time. However, the resolution of diffusion-weighted images is often limited by magnetic field inhomogeneity-related artifacts and blurring…

Image and Video Processing · Electrical Eng. & Systems 2023-09-26 Jaejin Cho , Yohan Jun , Xiaoqing Wang , Caique Kobayashi , Berkin Bilgic

Multi-spectral quantitative phase imaging (MS-QPI) is a cutting-edge label-free technique to determine the morphological changes, refractive index variations and spectroscopic information of the specimens. The bottleneck to implement this…