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In the field of medical image segmentation, tackling Out-of-Distribution (OOD) segmentation tasks in a cost-effective manner remains a significant challenge. Universal segmentation models is a solution, which aim to generalize across the…

Computer Vision and Pattern Recognition · Computer Science 2024-05-31 Lingdong Shen , Fangxin Shang , Xiaoshuang Huang , Yehui Yang , Haifeng Huang , Shiming Xiang

Multiple Instance Learning (MIL) is widely used in analyzing histopathological Whole Slide Images (WSIs). However, existing MIL methods do not explicitly model the data distribution, and instead they only learn a bag-level or instance-level…

Computer Vision and Pattern Recognition · Computer Science 2022-06-20 Linhao Qu , Xiaoyuan Luo , Shaolei Liu , Manning Wang , Zhijian Song

Vision-language models (VLMs) have recently been integrated into multiple instance learning (MIL) frameworks to address the challenge of few-shot, weakly supervised classification of whole slide images (WSIs). A key trend involves…

Computer Vision and Pattern Recognition · Computer Science 2025-12-15 Bryan Wong , Jong Woo Kim , Huazhu Fu , Mun Yong Yi

Multimodal in-context learning (ICL) remains underexplored despite significant potential for domains such as medicine. Clinicians routinely encounter diverse, specialized tasks requiring adaptation from limited examples, such as drawing…

Whole slide image (WSI) classification is a critical task in computational pathology, requiring the processing of gigapixel-sized images, which is challenging for current deep-learning methods. Current state of the art methods are based on…

Computer Vision and Pattern Recognition · Computer Science 2023-10-06 Jingwei Zhang , Saarthak Kapse , Ke Ma , Prateek Prasanna , Joel Saltz , Maria Vakalopoulou , Dimitris Samaras

Large vision-language models (LVLMs) employ multi-modal in-context learning (MM-ICL) to adapt to new tasks by leveraging demonstration examples. While increasing the number of demonstrations boosts performance, they incur significant…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Shin'ya Yamaguchi , Daiki Chijiwa , Tamao Sakao , Taku Hasegawa

Accurate analysis of histopathological images is critical for disease diagnosis and treatment planning. Whole-slide images (WSIs), which digitize tissue specimens at gigapixel resolution, are fundamental to this process but require…

Computer Vision and Pattern Recognition · Computer Science 2026-05-07 Enhui Chai , Sicheng Chen , Tianyi Zhang , Chad Wong , Kecheng Huang , Zeyu Liu , Fei Xia

Multiple Instance Learning (MIL) has become the predominant approach for classification tasks on gigapixel histopathology whole slide images (WSIs). Within the MIL framework, single WSIs (bags) are decomposed into patches (instances), with…

Computer Vision and Pattern Recognition · Computer Science 2023-03-03 Daniel Sens , Ario Sadafi , Francesco Paolo Casale , Nassir Navab , Carsten Marr

Deep learning has been extensively researched in the analysis of pathology whole-slide images (WSIs). However, most existing methods are limited to providing prediction interpretability by locating the model's salient areas in a post-hoc…

Machine Learning · Computer Science 2026-02-04 Zekang Yang , Hong Liu , Xiangdong Wang

Robust multimodal visual analytics remains challenging when heterogeneous modalities provide complementary but input-dependent evidence for decision-making.Existing multimodal learning methods mainly rely on fixed fusion modules or…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Tianyi Liu , Yiming Li , Wenqian Wang , Jiaojiao Wang , Chen Cai , Yi Wang , Kim-Hui Yap

State-of-the-art Vision-Language Models (VLMs) ground the vision and the language modality primarily via projecting the vision tokens from the encoder to language-like tokens, which are directly fed to the Large Language Model (LLM)…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Sivan Doveh , Shaked Perek , M. Jehanzeb Mirza , Wei Lin , Amit Alfassy , Assaf Arbelle , Shimon Ullman , Leonid Karlinsky

In-context learning (ICL) adapts LLMs by providing demonstrations without fine-tuning the model parameters; however, it does not differentiate between demonstrations and quadratically increases the complexity of Transformer LLMs, exhausting…

Computation and Language · Computer Science 2024-11-06 Giwon Hong , Emile van Krieken , Edoardo Ponti , Nikolay Malkin , Pasquale Minervini

Malignant brain tumors have become an aggressive and dangerous disease that leads to death worldwide.Multi-modal MRI data is crucial for accurate brain tumor segmentation, but missing modalities common in clinical practice can severely…

Methodology · Statistics 2025-07-11 Guoyan Liang , Qin Zhou , Jingyuan Chen , Bingcang Huang , Kai Chen , Lin Gu , Zhe Wang , Sai Wu , Chang Yao

Multiple Instance Learning (MIL) has been widely used in weakly supervised whole slide image (WSI) classification. Typical MIL methods include a feature embedding part, which embeds the instances into features via a pre-trained feature…

Computer Vision and Pattern Recognition · Computer Science 2024-08-02 Peijie Qiu , Pan Xiao , Wenhui Zhu , Yalin Wang , Aristeidis Sotiras

Bag-based Multiple Instance Learning (MIL) approaches have emerged as the mainstream methodology for Whole Slide Image (WSI) classification. However, most existing methods adopt a segmented training strategy, which first extracts features…

Computer Vision and Pattern Recognition · Computer Science 2025-03-13 Jiangping Wen , Jinyu Wen , Meie Fang

Multi-instance learning (MIL) is a widely-applied technique in practical applications that involve complex data structures. MIL can be broadly categorized into two types: traditional methods and those based on deep learning. These…

Artificial Intelligence · Computer Science 2023-04-25 Yu-Xuan Zhang , Zhengchun Zhou , Xingxing He , Avik Ranjan Adhikary , Bapi Dutta

The remarkable performance of large multimodal models (LMMs) has attracted significant interest from the image segmentation community. To align with the next-token-prediction paradigm, current LMM-driven segmentation methods either use…

Computer Vision and Pattern Recognition · Computer Science 2025-07-17 Tao Wang , Changxu Cheng , Lingfeng Wang , Senda Chen , Wuyue Zhao

Since the resurgence of deep learning, vision-language models (VLMs) enhanced by large language models (LLMs) have grown exponentially in popularity. However, while LLMs can utilize extensive background knowledge and task information with…

Computation and Language · Computer Science 2024-03-21 Haozhe Zhao , Zefan Cai , Shuzheng Si , Xiaojian Ma , Kaikai An , Liang Chen , Zixuan Liu , Sheng Wang , Wenjuan Han , Baobao Chang

Multimodal learning has shown promise in medical imaging, combining complementary modalities like images and text. Vision-language models (VLMs) capture rich diagnostic cues but often require large paired datasets and prompt- or text-based…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Banafsheh Karimian , Giulia Avanzato , Soufian Belharbi , Alexis Guichemerre , Luke McCaffrey , Mohammadhadi Shateri , Eric Granger

Whole Slide Image (WSI) classification has very significant applications in clinical pathology, e.g., tumor identification and cancer diagnosis. Currently, most research attention is focused on Multiple Instance Learning (MIL) using static…

Computer Vision and Pattern Recognition · Computer Science 2025-04-17 Jiaxiang Gou , Luping Ji , Pei Liu , Mao Ye
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