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Accurate grading of Conjunctival Melanocytic Intraepithelial Lesions (CMIL) is essential for treatment and melanoma prediction but remains difficult due to subtle morphological cues and interrelated diagnostic criteria. We introduce…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Mert Ikinci , Luna Toma , Karin U. Loeffler , Leticia Ussem , Daniela Süsskind , Julia M. Weller , Yousef Yeganeh , Martina C. Herwig-Carl , Shadi Albarqouni

Multiple Instance Learning is the predominant method for Whole Slide Image classification in digital pathology, enabling the use of slide-level labels to supervise model training. Although MIL eliminates the tedious fine-grained annotation…

Computer Vision and Pattern Recognition · Computer Science 2025-05-28 Chen Shu , Boyu Fu , Yiman Li , Ting Yin , Wenchuan Zhang , Jie Chen , Yuhao Yi , Hong Bu

In Large Visual Language Models (LVLMs), the efficacy of In-Context Learning (ICL) remains limited by challenges in cross-modal interactions and representation disparities. To overcome these challenges, we introduce a novel Visual…

Computer Vision and Pattern Recognition · Computer Science 2024-02-20 Yucheng Zhou , Xiang Li , Qianning Wang , Jianbing Shen

Conventional deep learning models deal with images one-by-one, requiring costly and time-consuming expert labeling in the field of medical imaging, and domain-specific restriction limits model generalizability. Visual in-context learning…

Multi-instance learning is common for computer vision tasks, especially in biomedical image processing. Traditional methods for multi-instance learning focus on designing feature aggregation methods and multi-instance classifiers, where the…

Computer Vision and Pattern Recognition · Computer Science 2021-03-18 Yanlun Tu , Houchao Lei , Wei Long , Yang Yang

Multiple instance learning (MIL) has emerged as a popular method for classifying histopathology whole slide images (WSIs). Existing approaches typically rely on frozen pre-trained models to extract instance features, neglecting the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-20 Yi Lin , Zhengjie Zhu , Kwang-Ting Cheng , Hao Chen

Multimodal learning that integrates genomics and histopathology has shown strong potential in cancer diagnosis, yet its clinical translation is hindered by the limited availability of paired histology-genomics data. Knowledge distillation…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Yongxin Guo , Hao Lu , Onur C. Koyun , Zhengjie Zhu , Muhammet Fatih Demir , Metin Nafi Gurcan

Multimodal in-context learning (ICL) has emerged as a key mechanism for harnessing the capabilities of large vision-language models (LVLMs). However, its effectiveness remains highly sensitive to the quality of input ICL sequences,…

Computation and Language · Computer Science 2025-10-22 Yanshu Li , Jianjiang Yang , Tian Yun , Pinyuan Feng , Jinfa Huang , Ruixiang Tang

This paper aims to model 3D human motion across domains, where a single model is expected to handle multiple modalities, tasks, and datasets. Existing cross-domain models often rely on domain-specific components and multi-stage training,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-15 Mengyuan Liu , Xinshun Wang , Zhongbin Fang , Deheng Ye , Xia Li , Tao Tang , Songtao Wu , Xiangtai Li , Ming-Hsuan Yang

Forensic pathology is critical in analyzing death manner and time from the microscopic aspect to assist in the establishment of reliable factual bases for criminal investigation. In practice, even the manual differentiation between…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Chen Shen , Jun Zhang , Xinggong Liang , Zeyi Hao , Kehan Li , Fan Wang , Zhenyuan Wang , Chunfeng Lian

Multiple Instance Learning (MIL) is the predominant framework for classifying gigapixel whole-slide images in computational pathology. MIL follows a sequence of 1) extracting patch features, 2) applying a linear layer to obtain…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Daniel Shao , Joel Runevic , Richard J. Chen , Drew F. K. Williamson , Ahrong Kim , Andrew H. Song , Faisal Mahmood

Multi-Instance Learning(MIL) aims to learn the mapping between a bag of instances and the bag-level label. Therefore, the relationships among instances are very important for learning the mapping. In this paper, we propose an MIL algorithm…

Machine Learning · Computer Science 2021-02-04 Yangling Ma , Zhouwang Yang

In many histopathology tasks, sample classification depends on morphological details in tissue or single cells that are only visible at the highest magnification. For a pathologist, this implies tedious zooming in and out, while for a…

Computer Vision and Pattern Recognition · Computer Science 2023-03-03 Ario Sadafi , Nassir Navab , Carsten Marr

Multiple instance learning (MIL) has enabled substantial progress in computational histopathology, where a large amount of patches from gigapixel whole slide images are aggregated into slide-level predictions. Heatmaps are widely used to…

Objective: Ulcerative colitis (UC), characterized by chronic inflammation with alternating remission-relapse cycles, requires precise histological healing (HH) evaluation to improve clinical outcomes. To overcome the limitations of…

Quantitative Methods · Quantitative Biology 2025-05-16 Zhengxuan Qiu , Bo Peng , Xiaoying Tang , Jiankun Wang , Qin Guo

Multimodal in-context learning (ICL) equips Large Vision-language Models (LVLMs) with the ability to adapt to new tasks via multiple user-provided demonstrations, without requiring any model parameter updates. However, its effectiveness is…

Computer Vision and Pattern Recognition · Computer Science 2025-08-27 Yanshu Li , Yi Cao , Hongyang He , Qisen Cheng , Xiang Fu , Xi Xiao , Tianyang Wang , Ruixiang Tang

Vision language models (VLM) pre-trained on datasets of histopathological image-caption pairs enabled zero-shot slide-level classification. The ability of VLM image encoders to extract discriminative features also opens the door for…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Pablo Meseguer , Rocío del Amor , Valery Naranjo

Recent advancements in video large multimodal models (LMMs) have significantly improved their video understanding and reasoning capabilities. However, their performance drops on out-of-distribution (OOD) tasks that are underrepresented in…

Computer Vision and Pattern Recognition · Computer Science 2024-12-04 Kangsan Kim , Geon Park , Youngwan Lee , Woongyeong Yeo , Sung Ju Hwang

In-context learning (ICL) enables large language models (LLMs) to perform downstream tasks through advanced prompting and high-quality demonstrations. However, traditional ICL paradigms encounter significant limitations in complex reasoning…

Computation and Language · Computer Science 2025-06-03 Jinyang Wu , Mingkuan Feng , Shuai Zhang , Feihu Che , Zengqi Wen , Chonghua Liao , Jianhua Tao

In clinical practice, crossmodal information including medical images and tabular data is essential for disease diagnosis. There exists a significant modality gap between these data types, which obstructs advancements in crossmodal…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Tianling Liu , Hongying Liu , Fanhua Shang , Lequan Yu , Tong Han , Liang Wan
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