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The parameter identifiability problem for a dynamical system is to determine whether the parameters of the system can be found from data for the outputs of the system. Verifying whether the parameters are identifiable is a necessary first…

Systems and Control · Electrical Eng. & Systems 2025-06-11 Alexey Ovchinnikov , Anand Pillay , Gleb Pogudin , Thomas Scanlon

Parameter identifiability describes whether, for a given differential model, one can determine parameter values from model equations. Knowing global or local identifiability properties allows construction of better practical experiments to…

Mathematical Software · Computer Science 2021-07-02 Ilia Ilmer , Alexey Ovchinnikov , Gleb Pogudin

Structural parameter identifiability is a property of a differential model with parameters that allows for the parameters to be determined from the model equations in the absence of noise. One of the standard approaches to assessing this…

Algebraic Geometry · Mathematics 2020-12-29 Alexey Ovchinnikov , Gleb Pogudin , Peter Thompson

A key step in mechanistic modelling of dynamical systems is to conduct a structural identifiability analysis. This entails deducing which parameter combinations can be estimated from a given set of observed outputs. The standard…

Optimization and Control · Mathematics 2026-03-30 Johannes G Borgqvist , Alexander P Browning , Fredrik Ohlsson , Ruth E Baker

Many real-world processes and phenomena are modeled using systems of ordinary differential equations with parameters. Given such a system, we say that a parameter is globally identifiable if it can be uniquely recovered from input and…

Classical Analysis and ODEs · Mathematics 2023-05-24 Hoon Hong , Alexey Ovchinnikov , Gleb Pogudin , Chee Yap

Interpreting data with mathematical models is an important aspect of real-world industrial and applied mathematical modeling. Often we are interested to understand the extent to which a particular set of data informs and constrains model…

Methodology · Statistics 2025-03-06 Matthew J Simpson , Ruth E Baker

Researchers develop models to explain the unknowns. These models typically involve parameters that capture tangible quantities, the estimation of which is desired. Parameter identifiability investigates the recoverability of the unknown…

Optimization and Control · Mathematics 2024-07-01 Anuththara Sarathchandra , Azadeh Aghaeeyan , Pouria Ramazi

Parameter identifiability is a structural property of an ODE model for recovering the values of parameters from the data (i.e., from the input and output variables). This property is a prerequisite for meaningful parameter identification in…

Systems and Control · Electrical Eng. & Systems 2021-06-07 Alexey Ovchinnikov , Anand Pillay , Gleb Pogudin , Thomas Scanlon

Differential equation models are crucial to scientific processes. The values of model parameters are important for analyzing the behaviour of solutions. A parameter is called globally identifiable if its value can be uniquely determined…

Quantitative Methods · Quantitative Biology 2024-02-07 Helen Byrne , Heather Harrington , Alexey Ovchinnikov , Gleb Pogudin , Hamid Rahkooy , Pedro Soto

Linear compartmental models are a widely used tool for analyzing systems arising in biology, medicine, and more. In such settings, it is essential to know whether model parameters can be recovered from experimental data. This is the…

Combinatorics · Mathematics 2025-11-18 Katherine Clemens , Jonathan Martinez , Anne Shiu , Michaela Thompson , Benjamin Warren

In parametric, nonlinear structural models a classical sufficient condition for local identification, like Fisher (1966) and Rothenberg (1971), is that the vector of moment conditions is differentiable at the true parameter with full rank…

Statistics Theory · Mathematics 2023-08-28 Xiaohong Chen , Victor Chernozhukov , Sokbae Lee , Whitney K. Newey

This work addresses the problem of identifiability, that is, the question of whether parameters can be recovered from data, for linear compartmental models. Using standard differential algebra techniques, the question of whether a given…

Algebraic Geometry · Mathematics 2021-06-30 Elizabeth Gross , Nicolette Meshkat , Anne Shiu

Symbolic recovery of differential equations is the ambitious attempt at automating the derivation of governing equations with the use of machine learning techniques. In contrast to classical methods which assume the structure of the…

Machine Learning · Computer Science 2024-10-10 Philipp Scholl , Aras Bacho , Holger Boche , Gitta Kutyniok

Probabilistic models often have parameters that can be translated, scaled, permuted, or otherwise transformed without changing the model. These symmetries can lead to strong correlation and multimodality in the posterior distribution over…

Machine Learning · Statistics 2013-12-20 Robert Nishihara , Thomas Minka , Daniel Tarlow

Scientists use mathematical modelling to understand and predict the properties of complex physical systems. In highly parameterised models there often exist relationships between parameters over which model predictions are identical, or…

Data Analysis, Statistics and Probability · Physics 2017-03-24 Dhruva V. Raman , James Anderson , Antonis Papachristodoulou

Identifiability is a necessary condition for successful parameter estimation of dynamic system models. A major component of identifiability analysis is determining the identifiable parameter combinations, the functional forms for the…

Quantitative Methods · Quantitative Biology 2013-10-07 Marisa C. Eisenberg , Michael A. L. Hayashi

Structural global parameter identifiability indicates whether one can determine a parameter's value in an ODE model from given inputs and outputs. If a given model has parameters for which there is exactly one value, such parameters are…

Systems and Control · Electrical Eng. & Systems 2024-10-08 Sebastian Falkensteiner , Alexey Ovchinnikov , J. Rafael Sendra

The well-known solution theory for (systems of) linear ordinary differential equations undergoes significant changes when introducing an additional real parameter. Properties like the existence of fundamental sets of solutions or…

Classical Analysis and ODEs · Mathematics 2021-03-22 Vyacheslav M. Boyko , Michael Kunzinger , Roman O. Popovych

Latent feature models (LFM)s are widely employed for extracting latent structures of data. While offering high, parameter estimation is difficult with LFMs because of the combinational nature of latent features, and non-identifiability is a…

Machine Learning · Computer Science 2018-09-27 Ryota Suzuki , Shingo Takahashi , Murtuza Petladwala , Shigeru Kohmoto

Online parameter identification is of importance, e.g., for model predictive control. Since the parameters have to be identified simultaneously to the process of the modeled system, dynamical update laws are used for state and parameter…

Numerical Analysis · Mathematics 2016-04-20 Romana Boiger , Barbara Kaltenbacher
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