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Accurately modeling multi-class cell topology is crucial in digital pathology, as it provides critical insights into tissue structure and pathology. The synthetic generation of cell topology enables realistic simulations of complex tissue…

Image and Video Processing · Electrical Eng. & Systems 2025-03-26 Meilong Xu , Saumya Gupta , Xiaoling Hu , Chen Li , Shahira Abousamra , Dimitris Samaras , Prateek Prasanna , Chao Chen

Image processing, including image restoration, image enhancement, etc., involves generating a high-quality clean image from a degraded input. Deep learning-based methods have shown superior performance for various image processing tasks in…

Computer Vision and Pattern Recognition · Computer Science 2024-07-31 Huiyu Duan , Xiongkuo Min , Sijing Wu , Wei Shen , Guangtao Zhai

In this paper, we introduce SemHiTok, a unified image Tokenizer via Semantic-Guided Hierarchical codebook that provides consistent discrete representations for multimodal understanding and generation. Recently, unified image tokenizers have…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Zisheng Chen , Chunwei Wang , Runhui Huang , Hongbin Xu , Xiuwei Chen , Jun Zhou , Jianhua Han , Hang Xu , Xiaodan Liang

Analyzing medical data to find abnormalities is a time-consuming and costly task, particularly for rare abnormalities, requiring tremendous efforts from medical experts. Artificial intelligence has become a popular tool for the automatic…

Brain CT report generation is significant to aid physicians in diagnosing cranial diseases. Recent studies concentrate on handling the consistency between visual and textual pathological features to improve the coherence of report. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-02 Chengxin Zheng , Junzhong Ji , Yanzhao Shi , Xiaodan Zhang , Liangqiong Qu

Computational Pathology (CPath) is an emerging field concerned with the study of tissue pathology via computational algorithms for the processing and analysis of digitized high-resolution images of tissue slides. Recent deep learning based…

Image and Video Processing · Electrical Eng. & Systems 2021-12-20 Amina Asif , Kashif Rajpoot , David Snead , Fayyaz Minhas , Nasir Rajpoot

Humans paint images incrementally: they plan a global layout, sketch a coarse draft, inspect, and refine details, and most importantly, each step is grounded in the evolving visual states. However, can unified multimodal models trained on…

Computer Vision and Pattern Recognition · Computer Science 2026-04-09 Lei Zhang , Junjiao Tian , Zhipeng Fan , Kunpeng Li , Jialiang Wang , Weifeng Chen , Markos Georgopoulos , Felix Juefei-Xu , Yuxiang Bao , Julian McAuley , Manling Li , Zecheng He

Foundation models have emerged as a powerful paradigm in computational pathology (CPath), enabling scalable and generalizable analysis of histopathological images. While early developments centered on uni-modal models trained solely on…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Dong Li , Guihong Wan , Xintao Wu , Xinyu Wu , Xiaohui Chen , Yi He , Christine G. Lian , Peter K. Sorger , Yevgeniy R. Semenov , Chen Zhao

Recent visual generation models have made major progress in photorealism, typography, instruction following, and interactive editing, yet they still struggle with spatial reasoning, persistent state, long-horizon consistency, and causal…

Synthesizing a subject-specific pathology-free image from a pathological image is valuable for algorithm development and clinical practice. In recent years, several approaches based on the Generative Adversarial Network (GAN) have achieved…

Image and Video Processing · Electrical Eng. & Systems 2022-03-30 Yunlong Zhang , Xin Lin , Yihong Zhuang , LiyanSun , Yue Huang , Xinghao Ding , Guisheng Wang , Lin Yang , Yizhou Yu

Recent breakthroughs in self-supervised learning have enabled the use of large unlabeled datasets to train visual foundation models that can generalize to a variety of downstream tasks. While this training paradigm is well suited for the…

Computational pathology can lead to saving human lives, but models are annotation hungry and pathology images are notoriously expensive to annotate. Self-supervised learning has shown to be an effective method for utilizing unlabeled data,…

Computer Vision and Pattern Recognition · Computer Science 2023-04-19 Mingu Kang , Heon Song , Seonwook Park , Donggeun Yoo , Sérgio Pereira

Recent advancements in Generative Artificial Intelligence (GenAI) have significantly enhanced the capabilities of both image generation and editing. However, current approaches often treat these tasks separately, leading to inefficiencies…

Computer Vision and Pattern Recognition · Computer Science 2026-01-30 Thanh-Nhan Vo , Trong-Thuan Nguyen , Tam V. Nguyen , Minh-Triet Tran

While Vision-Language Models (VLMs) have achieved notable progress in computational pathology (CPath), the gigapixel scale and spatial heterogeneity of Whole Slide Images (WSIs) continue to pose challenges for multimodal understanding.…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Fengchun Liu , Songhan Jiang , Linghan Cai , Ziyue Wang , Yongbing Zhang

Tokenizer is a crucial component for both visual understanding and generation. To advance toward the ultimate goal of universal modeling, recent research has focused on developing a unified tokenizer. However, existing tokenizers face a…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Zhengrong Yue , Haiyu Zhang , Xiangyu Zeng , Boyu Chen , Chenting Wang , Shaobin Zhuang , Lu Dong , Yi Wang , Limin Wang , Yali Wang

Although Vision Language Models (VLMs) have shown strong generalization in medical imaging, pathology presents unique challenges due to ultra-high resolution, complex tissue structures, and nuanced clinical semantics. These factors make…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Wenchuan Zhang , Jingru Guo , Hengzhe Zhang , Penghao Zhang , Jie Chen , Shuwan Zhang , Zhang Zhang , Yuhao Yi , Hong Bu

Automatic histopathology image segmentation is crucial to disease analysis. Limited available labeled data hinders the generalizability of trained models under the fully supervised setting. Semi-supervised learning (SSL) based on generative…

Computer Vision and Pattern Recognition · Computer Science 2020-12-18 Hongxiao Wang , Hao Zheng , Jianxu Chen , Lin Yang , Yizhe Zhang , Danny Z. Chen

Tissue semantic segmentation is one of the key tasks in computational pathology. To avoid the expensive and laborious acquisition of pixel-level annotations, a wide range of studies attempt to adopt the class activation map (CAM), a…

Computer Vision and Pattern Recognition · Computer Science 2024-12-31 Zijie Fang , Yifeng Wang , Peizhang Xie , Zhi Wang , Yongbing Zhang

Medical diagnostic applications require models that can process multimodal medical inputs (images, patient histories, lab results) and generate diverse outputs including both textual reports and visual content (annotations, segmentation…

Deep learning is widely applied in computer-aided pathological diagnosis, which alleviates the pathologist workload and provide timely clinical analysis. However, most models generally require large-scale annotated data for training, which…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Zeyu Liu , Tianyi Zhang , Yufang He , Yunlu Feng , Yu Zhao , Guanglei Zhang