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Controllable image synthesis models allow creation of diverse images based on text instructions or guidance from a reference image. Recently, denoising diffusion probabilistic models have been shown to generate more realistic imagery than…

Computer Vision and Pattern Recognition · Computer Science 2022-12-06 Xihui Liu , Dong Huk Park , Samaneh Azadi , Gong Zhang , Arman Chopikyan , Yuxiao Hu , Humphrey Shi , Anna Rohrbach , Trevor Darrell

Multimodal pathological image understanding has garnered widespread interest due to its potential to improve diagnostic accuracy and enable personalized treatment through integrated visual and textual data. However, existing methods exhibit…

Computer Vision and Pattern Recognition · Computer Science 2025-05-22 Zhe Xu , Cheng Jin , Yihui Wang , Ziyi Liu , Hao Chen

The remarkable success of diffusion models in text-to-image generation has sparked growing interest in expanding their capabilities to a variety of multi-modal tasks, including image understanding, manipulation, and perception. These tasks…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Xinyang Song , Libin Wang , Weining Wang , Shaozhen Liu , Dandan Zheng , Jingdong Chen , Qi Li , Zhenan Sun

In computational pathology, researchers often face challenges due to the scarcity of labeled pathology datasets. Data augmentation emerges as a crucial technique to mitigate this limitation. In this study, we introduce an efficient data…

Computer Vision and Pattern Recognition · Computer Science 2025-02-25 Jiamu Wang , Jin Tae Kwak

Computational Pathology CPath is an interdisciplinary science that augments developments of computational approaches to analyze and model medical histopathology images. The main objective for CPath is to develop infrastructure and workflows…

Achieving machine autonomy and human control often represent divergent objectives in the design of interactive AI systems. Visual generative foundation models such as Stable Diffusion show promise in navigating these goals, especially when…

Computer Vision and Pattern Recognition · Computer Science 2023-11-03 Can Qin , Shu Zhang , Ning Yu , Yihao Feng , Xinyi Yang , Yingbo Zhou , Huan Wang , Juan Carlos Niebles , Caiming Xiong , Silvio Savarese , Stefano Ermon , Yun Fu , Ran Xu

Multimodal large language models (MLLMs) have emerged as powerful tools for computational pathology, offering unprecedented opportunities to integrate pathological images with language context for comprehensive diagnostic analysis. These…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Zhe Xu , Ziyi Liu , Junlin Hou , Jiabo Ma , Cheng Jin , Yihui Wang , Zhixuan Chen , Zhengyu Zhang , Fuxiang Huang , Zhengrui Guo , Fengtao Zhou , Yingxue Xu , Xi Wang , Ronald Cheong Kin Chan , Li Liang , Hao Chen

The recognition of multi-class cell nuclei can significantly facilitate the process of histopathological diagnosis. Numerous pathological datasets are currently available, but their annotations are inconsistent. Most existing methods…

Computer Vision and Pattern Recognition · Computer Science 2024-02-21 Junjia Huang , Haofeng Li , Xiang Wan , Guanbin Li

Text-to-Image diffusion models have made tremendous progress over the past two years, enabling the generation of highly realistic images based on open-domain text descriptions. However, despite their success, text descriptions often…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Shihao Zhao , Dongdong Chen , Yen-Chun Chen , Jianmin Bao , Shaozhe Hao , Lu Yuan , Kwan-Yee K. Wong

Recent advances in vision language models (VLMs) have enabled broad progress in the general medical field. However, pathology still remains a more challenging subdomain, with current pathology specific VLMs exhibiting limitations in both…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Wenchuan Zhang , Penghao Zhang , Jingru Guo , Tao Cheng , Jie Chen , Shuwan Zhang , Zhang Zhang , Yuhao Yi , Hong Bu

Foundation models have revolutionized computational pathology by achieving remarkable success in high-level diagnostic tasks, yet the critical challenge of low-level image enhancement remains largely unaddressed. Real-world pathology images…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Ziyi Liu , Zhe Xu , Jiabo Ma , Wenqaing Li , Junlin Hou , Fuxiang Huang , Xi Wang , Ronald Cheong Kin Chan , Terence Tsz Wai Wong , Hao Chen

Histopathology image classification is crucial for the accurate identification and diagnosis of various diseases but requires large and diverse datasets. Obtaining such datasets, however, is often costly and time-consuming due to the need…

Computer Vision and Pattern Recognition · Computer Science 2024-09-25 Leire Benito-Del-Valle , Aitor Alvarez-Gila , Itziar Eguskiza , Cristina L. Saratxaga

Automated generation of diagnostic pathology reports directly from whole slide images (WSIs) is an emerging direction in computational pathology. Translating high-resolution tissue patterns into clinically coherent text remains difficult…

Computer Vision and Pattern Recognition · Computer Science 2025-12-16 Noorul Wahab , Nasir Rajpoot

Recent advances in text-to-image generation with diffusion models present transformative capabilities in image quality. However, user controllability of the generated image, and fast adaptation to new tasks still remains an open challenge,…

Computer Vision and Pattern Recognition · Computer Science 2023-02-17 Omer Bar-Tal , Lior Yariv , Yaron Lipman , Tali Dekel

Pathology is experiencing rapid digital transformation driven by whole-slide imaging and artificial intelligence (AI). While deep learning-based computational pathology has achieved notable success, traditional models primarily focus on…

Photorealistic image generation from simulated label maps are necessitated in several contexts, such as for medical training in virtual reality. With conventional deep learning methods, this task requires images that are paired with…

Computer Vision and Pattern Recognition · Computer Science 2023-02-22 Lin Zhang , Tiziano Portenier , Orcun Goksel

Novel multimodal imaging methods are capable of generating extensive, super high resolution datasets for preclinical research. Yet, a massive lack of annotations prevents the broad use of deep learning to analyze such data. So far, existing…

Image and Video Processing · Electrical Eng. & Systems 2021-04-26 Izabela Horvath , Johannes C. Paetzold , Oliver Schoppe , Rami Al-Maskari , Ivan Ezhov , Suprosanna Shit , Hongwei Li , Ali Ertuerk , Bjoern H. Menze

Foundation models in digital pathology use massive datasets to learn useful compact feature representations of complex histology images. However, there is limited transparency into what drives the correlation between dataset size and…

Real-world graphs exhibit increasing heterophily, where nodes no longer tend to be connected to nodes with the same label, challenging the homophily assumption of classical graph neural networks (GNNs) and impeding their performance.…

Machine Learning · Computer Science 2024-08-22 Jiajun Zhou , Chenxuan Xie , Shengbo Gong , Jiaxu Qian , Shanqing Yu , Qi Xuan , Xiaoniu Yang

Deep learning has been increasingly incorporated into various computational pathology applications to improve its efficiency, accuracy, and robustness. Although successful, most previous approaches for image classification have crucial…

Image and Video Processing · Electrical Eng. & Systems 2024-07-15 Anh Tien Nguyen , Jin Tae Kwak