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Personalized text-to-image generation aims to create images tailored to user-defined concepts and textual descriptions. Balancing the fidelity of the learned concept with its ability for generation in various contexts presents a significant…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Vera Soboleva , Maksim Nakhodnov , Aibek Alanov

The integration of artificial intelligence into digital pathology has the potential to automate and improve various tasks, such as image analysis and diagnostic decision-making. Yet, the inherent variability of tissues, together with the…

Image and Video Processing · Electrical Eng. & Systems 2023-02-14 Ariel Larey , Nati Daniel , Eliel Aknin , Yael Fisher , Yonatan Savir

Pathology image analysis plays a pivotal role in medical diagnosis, with deep learning techniques significantly advancing diagnostic accuracy and research. While numerous studies have been conducted to address specific pathological tasks,…

Image and Video Processing · Electrical Eng. & Systems 2025-03-31 Dankai Liao , Sicheng Chen , Nuwa Xi , Qiaochu Xue , Jieyu Li , Lingxuan Hou , Zeyu Liu , Chang Han Low , Yufeng Wu , Yiling Liu , Yanqin Jiang , Dandan Li , Shangqing Lyu

Conventional histopathology has long been essential for disease diagnosis, relying on visual inspection of tissue sections. Immunohistochemistry aids in detecting specific biomarkers but is limited by its single-marker approach, restricting…

The examination of histopathology images is considered to be the gold standard for the diagnosis and stratification of cancer patients. A key challenge in the analysis of such images is their size, which can run into the gigapixels and can…

Image and Video Processing · Electrical Eng. & Systems 2021-09-09 Joseph Boyd , Mykola Liashuha , Eric Deutsch , Nikos Paragios , Stergios Christodoulidis , Maria Vakalopoulou

Advances in AI have introduced several strong models in computational pathology to usher it into the era of multi-modal diagnosis, analysis, and interpretation. However, the current pathology-specific visual language models still lack…

Tissue phenotyping is a fundamental computational pathology (CPath) task in learning objective characterizations of histopathologic biomarkers in anatomic pathology. However, whole-slide imaging (WSI) poses a complex computer vision problem…

Understanding the relationship between pathological and healthy brain structures is fundamental to neuroimaging, connecting disease diagnosis and detection with modeling, prediction, and treatment planning. However, paired…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Jun Wang , Peirong Liu

Artificial intelligence and machine learning techniques have the promise to revolutionize the field of digital pathology. However, these models demand considerable amounts of data, while the availability of unbiased training data is…

Image and Video Processing · Electrical Eng. & Systems 2023-02-14 Nati Daniel , Eliel Aknin , Ariel Larey , Yoni Peretz , Guy Sela , Yael Fisher , Yonatan Savir

With the rapid development of computational pathology, many AI-assisted diagnostic tasks have emerged. Cellular nuclei segmentation can segment various types of cells for downstream analysis, but it relies on predefined categories and lacks…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Chunlin Zhong , Shuang Hao , Junhua Wu , Xiaona Chang , Jiwei Jiang , Xiu Nie , He Tang , Xiang Bai

The emergence of large multimodal models (LMMs) has brought significant advancements to pathology. Previous research has primarily focused on separately training patch-level and whole-slide image (WSI)-level models, limiting the integration…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Yuxuan Sun , Yixuan Si , Chenglu Zhu , Xuan Gong , Kai Zhang , Pingyi Chen , Ye Zhang , Zhongyi Shui , Tao Lin , Lin Yang

Synthetic data generation in histopathology faces unique challenges: preserving tissue heterogeneity, capturing subtle morphological features, and scaling to unannotated datasets. We present a latent diffusion model that generates realistic…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Saghir Alfasly , Wataru Uegami , MD Enamul Hoq , Ghazal Alabtah , H. R. Tizhoosh

Recent advancements in multimodal pre-training models have significantly advanced computational pathology. However, current approaches predominantly rely on visual-language models, which may impose limitations from a molecular perspective…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Minghao Han , Dingkang Yang , Jiabei Cheng , Xukun Zhang , Linhao Qu , Zizhi Chen , Lihua Zhang

A visual metaphor constitutes a high-order form of human creativity, employing cross-domain semantic fusion to transform abstract concepts into impactful visual rhetoric. Despite the remarkable progress of generative AI, existing models…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Yu Xu , Yuxin Zhang , Juan Cao , Lin Gao , Chunyu Wang , Oliver Deussen , Tong-Yee Lee , Fan Tang

Whole slide imaging (WSI) has transformed digital pathology by enabling computational analysis of gigapixel histopathology images. Recent foundation model advances have accelerated progress in computational pathology, facilitating joint…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Peihang Wu , Zehong Chen , Lijian Xu

Text-to-image generation has greatly advanced content creation, yet accurately rendering visual text remains a key challenge due to blurred glyphs, semantic drift, and limited style control. Existing methods often rely on pre-rendered glyph…

Computer Vision and Pattern Recognition · Computer Science 2025-07-03 Yuanrui Wang , Cong Han , Yafei Li , Zhipeng Jin , Xiawei Li , SiNan Du , Wen Tao , Yi Yang , Shuanglong Li , Chun Yuan , Liu Lin

Scarcity of annotated data, particularly for rare or atypical morphologies, present significant challenges for cell and nuclei segmentation in computational pathology. While manual annotation is labor-intensive and costly, synthetic data…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Dominik Winter , Mai Bui , Monica Azqueta Gavaldon , Nicolas Triltsch , Marco Rosati , Nicolas Brieu

Recent years have witnessed remarkable progress in multimodal learning within computational pathology. Existing models primarily rely on vision and language modalities; however, language alone lacks molecular specificity and offers limited…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Minghao Han , Dingkang Yang , Linhao Qu , Zizhi Chen , Gang Li , Han Wang , Jiacong Wang , Lihua Zhang

We introduce UniToken, an auto-regressive generation model that encodes visual inputs through a combination of discrete and continuous representations, enabling seamless integration of unified visual understanding and image generation…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Yang Jiao , Haibo Qiu , Zequn Jie , Shaoxiang Chen , Jingjing Chen , Lin Ma , Yu-Gang Jiang

The accelerated adoption of digital pathology and advances in deep learning have enabled the development of powerful models for various pathology tasks across a diverse array of diseases and patient cohorts. However, model training is often…