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Advanced microscopy techniques are essential in biomedical research for visualising and tracking biomolecules within living cells and their compartments. Conventional fluorescence microscopy methods, however, often struggle with accurately…

Large Language Models (LLMs) have become an indispensable part of natural language processing tasks. However, autoregressive sampling has become an efficiency bottleneck. Multi-Draft Speculative Decoding (MDSD) is a recent approach where,…

Computation and Language · Computer Science 2025-02-27 Zhengmian Hu , Tong Zheng , Vignesh Viswanathan , Ziyi Chen , Ryan A. Rossi , Yihan Wu , Dinesh Manocha , Heng Huang

Super-resolution microscopy is rapidly gaining importance as an analytical tool in the life sciences. A compelling feature is the ability to label biological units of interest with fluorescent markers in living cells and to observe them…

Super-resolution microscopy normally requiring complex and cumbersome optics is not applicable for in situ imaging through a narrow channel. Here, we demonstrate single hair-thin multimode fiber (MMF) endoscope (less than 250 ${\mu}m$) for…

We present a novel spectral learning algorithm for simultaneous localization and mapping (SLAM) from range data with known correspondences. This algorithm is an instance of a general spectral system identification framework, from which it…

Machine Learning · Computer Science 2012-07-12 Byron Boots , Geoffrey J. Gordon

We study an inverse problem for Light Sheet Fluorescence Microscopy (LSFM), where the density of fluorescent molecules needs to be reconstructed. Our first step is to present a mathematical model to describe the measurements obtained by an…

Analysis of PDEs · Mathematics 2020-08-26 Evelyn Cueva , Matias Courdurier , Axel Osses , Victor Castañeda , Benjamin Palacios , Steffen Härtel

Simultaneous Localization and Mapping (SLAM) algorithms perform visual-inertial estimation via filtering or batch optimization methods. Empirical evidence suggests that filtering algorithms are computationally faster, while optimization…

Systems and Control · Electrical Eng. & Systems 2022-08-05 Amay Saxena , Chih-Yuan Chiu , Joseph Menke , Ritika Shrivastava , Shankar Sastry

Self-supervised vision-language pretraining from pure images and text with a contrastive loss is effective, but ignores fine-grained alignment due to a dual-stream architecture that aligns image and text representations only on a global…

Computer Vision and Pattern Recognition · Computer Science 2022-07-29 Zaid Khan , Vijay Kumar BG , Xiang Yu , Samuel Schulter , Manmohan Chandraker , Yun Fu

Fast and accurate object perception in low-light traffic scenes has attracted increasing attention. However, due to severe illumination degradation and the lack of reliable visual cues, existing perception models and methods struggle to…

Computer Vision and Pattern Recognition · Computer Science 2025-09-08 Hulin Li , Qiliang Ren , Jun Li , Hanbing Wei , Zheng Liu , Linfang Fan

Weakly Supervised Semantic Segmentation (WSSS) with image-level labels has long been suffering from fragmentary object regions led by Class Activation Map (CAM), which is incapable of generating fine-grained masks for semantic segmentation.…

Computer Vision and Pattern Recognition · Computer Science 2023-03-07 Jiren Mai , Fei Zhang , Junjie Ye , Marcus Kalander , Xian Zhang , WanKou Yang , Tongliang Liu , Bo Han

Free-form strong-lensing (SL) mass reconstructions typically suffer from overfitting, which manifest itself as false-positive small-scale fluctuations. We present a new free-form MAximum-entropy ReconStruction (${\tt MARS}$) method without…

Cosmology and Nongalactic Astrophysics · Physics 2022-06-08 Sangjun Cha , M. James Jee

Recent segmentation methods leveraging Multi-modal Large Language Models (MLLMs) have shown reliable object-level segmentation and enhanced spatial perception. However, almost all previous methods predominantly rely on specialist mask…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Anqi Zhang , Xiaokang Ji , Guangyu Gao , Jianbo Jiao , Chi Harold Liu , Yunchao Wei

Recent advances in large-scale optimal transport have greatly extended its application scenarios in machine learning. However, existing methods either not explicitly learn the transport map or do not support general cost function. In this…

Computer Vision and Pattern Recognition · Computer Science 2020-03-17 Guansong Lu , Zhiming Zhou , Jian Shen , Cheng Chen , Weinan Zhang , Yong Yu

Structured illumination microscopy (SIM) has become an important technique for optical super-resolution imaging because it allows a doubling of image resolution at speeds compatible for live-cell imaging. However, the reconstruction of SIM…

Image and Video Processing · Electrical Eng. & Systems 2020-03-26 Charles N. Christensen , Edward N. Ward , Pietro Lio , Clemens F. Kaminski

We propose a continuous non-convex variational model for Single Molecule Localisation Microscopy (SMLM) super-resolution in order to overcome light diffraction barriers. Namely, we consider a variation of the Continuous Exact $\ell_0$…

Image and Video Processing · Electrical Eng. & Systems 2020-10-27 Marta Lazzaretti , Luca Calatroni , Claudio Estatico

Live-cell imaging of multiple subcellular structures is essential for understanding subcellular dynamics. However, the conventional multi-color sequential fluorescence microscopy suffers from significant imaging delays and limited number of…

Subcellular Processes · Quantitative Biology 2025-01-13 Mingyang Chen , Luhong Jin , Xuwei Xuan , Defu Yang , Yun Cheng , Ju Zhang

Brain pathologies often manifest as partial or complete loss of tissue. The goal of many neuroimaging studies is to capture the location and amount of tissue changes with respect to a clinical variable of interest, such as disease…

Computer Vision and Pattern Recognition · Computer Science 2022-08-12 Samuel Gerber , Marc Niethammer , Ebrahim Ebrahim , Joseph Piven , Stephen R. Dager , Martin Styner , Stephen Aylward , Andinet Enquobahrie

Fast 3D super-resolution imaging is essential for decoding rapidly occurring biological processes. Encoding single molecules to their respective planes enable simultaneous multi-plane super-resolution volume imaging. This saves the…

Biological Physics · Physics 2016-08-04 Partha Pratim Mondal

Space-division multiplexing is a promising technology in optical fibre communication to improve the transmission capacity of a single optical fibre. However, the number of channels that can be multiplexed is limited by the crosstalks…

Optics · Physics 2020-02-06 Pengfei Fan , Michael Ruddlesden , Yufei Wang , Luming Zhao , Chao Lu , Lei Su

Model merging provides a compelling paradigm for integrating specialized expertise into a unified multi-task model, a goal that aligns naturally with the sequential knowledge acquisition in continual learning (CL). However, the requirement…

Machine Learning · Computer Science 2026-05-12 Xi Wang , Cheng Deng