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The rapid growth of biomedical knowledge has outpaced our ability to efficiently extract insights and generate novel hypotheses. Large language models (LLMs) have emerged as a promising tool to revolutionize knowledge interaction and…

Computation and Language · Computer Science 2024-07-16 Biqing Qi , Kaiyan Zhang , Kai Tian , Haoxiang Li , Zhang-Ren Chen , Sihang Zeng , Ermo Hua , Hu Jinfang , Bowen Zhou

As language models (LMs) become capable of handling a wide range of tasks, their evaluation is becoming as challenging as their development. Most generation benchmarks currently assess LMs using abstract evaluation criteria like helpfulness…

The rapid rise in popularity of Large Language Models (LLMs) with emerging capabilities has spurred public curiosity to evaluate and compare different LLMs, leading many researchers to propose their own LLM benchmarks. Noticing preliminary…

Artificial Intelligence · Computer Science 2025-05-15 Timothy R. McIntosh , Teo Susnjak , Nalin Arachchilage , Tong Liu , Paul Watters , Malka N. Halgamuge

The increasing use of Large Language Models (LLMs) offers significant opportunities across the engineering lifecycle, including requirements engineering, software development, process optimization, and decision support. Despite this…

Software Engineering · Computer Science 2026-02-05 Stefan Otten , Philipp Reis , Philipp Rigoll , Joshua Ransiek , Tobias Schürmann , Jacob Langner , Eric Sax

Large language models (LLMs) have strong capabilities in solving diverse natural language processing tasks. However, the safety and security issues of LLM systems have become the major obstacle to their widespread application. Many studies…

Computation and Language · Computer Science 2024-01-12 Tianyu Cui , Yanling Wang , Chuanpu Fu , Yong Xiao , Sijia Li , Xinhao Deng , Yunpeng Liu , Qinglin Zhang , Ziyi Qiu , Peiyang Li , Zhixing Tan , Junwu Xiong , Xinyu Kong , Zujie Wen , Ke Xu , Qi Li

The emergence of Generative AI (Gen AI) and Large Language Models (LLMs) has enabled more advanced chatbots capable of human-like interactions. However, these conversational agents introduce a broader set of operational risks that extend…

Cryptography and Security · Computer Science 2025-05-09 Pedro Pinacho-Davidson , Fernando Gutierrez , Pablo Zapata , Rodolfo Vergara , Pablo Aqueveque

The rapid advancement of artificial intelligence has raised concerns about its potential to facilitate biological weapons development. We argue existing safety assessments of contemporary foundation AI models underestimate this risk,…

Computers and Society · Computer Science 2025-06-18 Roger Brent , T. Greg McKelvey

In an era where digital threats are increasingly sophisticated, the intersection of Artificial Intelligence and cybersecurity presents both promising defenses and potent dangers. This paper delves into the escalating threat posed by the…

Cryptography and Security · Computer Science 2024-08-26 Yusuf Usman , Aadesh Upadhyay , Prashnna Gyawali , Robin Chataut

The literature and multiple experts point to many potential risks from large language models (LLMs), but there are still very few direct measurements of the actual harms posed. AI risk assessment has so far focused on measuring the models'…

Artificial Intelligence · Computer Science 2025-03-11 Malcolm Murray , Henry Papadatos , Otter Quarks , Pierre-François Gimenez , Simeon Campos

Large Language Models (LLMs) have transformed how people interact with artificial intelligence (AI) systems, achieving state-of-the-art results in various tasks, including scientific discovery and hypothesis generation. However, the lack of…

Computation and Language · Computer Science 2024-11-06 Sikun Guo , Amir Hassan Shariatmadari , Guangzhi Xiong , Albert Huang , Eric Xie , Stefan Bekiranov , Aidong Zhang

As frontier Large Language Models (LLMs) increasingly saturate new benchmarks shortly after they are published, benchmarking itself is at a juncture: if frontier models keep improving, it will become increasingly hard for humans to generate…

This study systematically evaluates 27 frontier Large Language Models on eight biology benchmarks spanning molecular biology, genetics, cloning, virology, and biosecurity. Models from major AI developers released between November 2022 and…

Machine Learning · Computer Science 2025-05-23 Lennart Justen

The perception that the convergence of biological engineering and artificial intelligence (AI) could enable increased biorisk has recently drawn attention to the governance of biotechnology and artificial intelligence. The 2023 Executive…

Computers and Society · Computer Science 2024-06-12 Matthew E. Walsh

Artificial intelligence (AI) is increasingly being used to augment and automate cyber operations, altering the scale, speed, and accessibility of malicious activity. These shifts raise urgent questions about when AI systems introduce…

Cryptography and Security · Computer Science 2026-01-27 Krystal Jackson , Deepika Raman , Jessica Newman , Nada Madkour , Charlotte Yuan , Evan R. Murphy

Artificial Intelligence (AI) is revolutionizing scientific research, yet its growing integration into laboratory environments presents critical safety challenges. Large language models (LLMs) and vision language models (VLMs) now assist in…

As generative large model capabilities advance, safety concerns become more pronounced in their outputs. To ensure the sustainable growth of the AI ecosystem, it's imperative to undertake a holistic evaluation and refinement of associated…

Artificial Intelligence · Computer Science 2023-12-01 Jiawen Deng , Jiale Cheng , Hao Sun , Zhexin Zhang , Minlie Huang

Large language models (LLMs) have become important tools in solving biological problems, offering improvements in accuracy and adaptability over conventional methods. Several benchmarks have been proposed to evaluate the performance of…

This paper provides a comprehensive review of the future of cybersecurity through Generative AI and Large Language Models (LLMs). We explore LLM applications across various domains, including hardware design security, intrusion detection,…

Retrieval-augmented generation (RAG) systems have become widely used for enhancing large language model capabilities, but they introduce significant security vulnerabilities through prompt injection attacks. We present a comprehensive…

Cryptography and Security · Computer Science 2025-11-21 Badrinath Ramakrishnan , Akshaya Balaji