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Artificial intelligence (AI) has transformed imaging inverse problems, from medical diagnostics to Earth observation. Yet deep neural networks can produce hallucinations, realistic-looking but incorrect details, undermining their…

Machine Learning · Statistics 2026-05-14 David Iagaru , Nina M. Gottschling , Anders C. Hansen , Josselin Garnier

Tomographic image reconstruction is generally an ill-posed linear inverse problem. Such ill-posed inverse problems are typically regularized using prior knowledge of the sought-after object property. Recently, deep neural networks have been…

Image and Video Processing · Electrical Eng. & Systems 2021-09-28 Sayantan Bhadra , Varun A. Kelkar , Frank J. Brooks , Mark A. Anastasio

Uncertainty quantification in inverse medical imaging tasks with deep learning has received little attention. However, deep models trained on large data sets tend to hallucinate and create artifacts in the reconstructed output that are not…

Image and Video Processing · Electrical Eng. & Systems 2020-08-21 Max-Heinrich Laves , Malte Tölle , Tobias Ortmaier

Poor performance of quantitative analysis in histopathological Whole Slide Images (WSI) has been a significant obstacle in clinical practice. Annotating large-scale WSIs manually is a demanding and time-consuming task, unlikely to yield the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Sarah Cechnicka , James Ball , Hadrien Reynaud , Callum Arthurs , Candice Roufosse , Bernhard Kainz

The widespread adoption of large language and vision models in real-world applications has made urgent the need to address hallucinations -- instances where models produce incorrect or nonsensical outputs. These errors can propagate…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Zhengyi Ho , Siyuan Liang , Dacheng Tao

Generative image reconstruction algorithms such as measurement conditioned diffusion models are increasingly popular in the field of medical imaging. These powerful models can transform low signal-to-noise ratio (SNR) inputs into outputs…

Medical Physics · Physics 2024-07-18 Matthew Tivnan , Siyeop Yoon , Zhennong Chen , Xiang Li , Dufan Wu , Quanzheng Li

Hallucinations are an inescapable consequence of solving inverse problems with deep neural networks. The expressiveness of recent generative models is the reason why they can yield results far superior to conventional regularizers; it can…

Instrumentation and Methods for Astrophysics · Physics 2023-06-26 Matt L. Sampson , Peter Melchior

Contemporary face hallucination (FH) models exhibit considerable ability to reconstruct high-resolution (HR) details from low-resolution (LR) face images. This ability is commonly learned from examples of corresponding HR-LR image pairs,…

Computer Vision and Pattern Recognition · Computer Science 2018-12-24 Klemen Grm , Martin Pernuš , Leo Cluzel , Walter Scheirer , Simon Dobrišek , Vitomir Štruc

Generative models are prone to hallucinations: plausible but incorrect structures absent in the ground truth. This issue is problematic in image restoration for safety-critical domains such as medical imaging, industrial inspection, and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-04 Seunghoi Kim , Henry F. J. Tregidgo , Chen Jin , Matteo Figini , Daniel C. Alexander

With fast developments in computational power and algorithms, deep learning has made breakthroughs and been applied in many fields. However, generalization remains to be a critical challenge, and the limited generalization capability…

Digitized histopathology glass slides, known as Whole Slide Images (WSIs), are often several gigapixels large and contain sensitive metadata information, which makes distributed processing unfeasible. Moreover, artifacts in WSIs may result…

Computational Engineering, Finance, and Science · Computer Science 2023-09-14 Yuandou Wang , Neel Kanwal , Kjersti Engan , Chunming Rong , Zhiming Zhao

Whole slide images~(WSIs) are digitized images of tissues placed in glass slides using advanced scanners. The digital processing of WSIs is challenging as they are gigapixel images and stored in multi-resolution format. A common challenge…

Image and Video Processing · Electrical Eng. & Systems 2023-10-30 Saba Heidari Gheshlaghi , Milan Aryal , Nasim Yahyasoltani , Masoud Ganji

Unsupervised hallucination detection aims to identify hallucinated content generated by large language models (LLMs) without relying on labeled data. While unsupervised methods have gained popularity by eliminating labor-intensive human…

Computation and Language · Computer Science 2025-09-15 Ponhvoan Srey , Xiaobao Wu , Anh Tuan Luu

Colloquially speaking, image generation models based upon diffusion processes are frequently said to exhibit "hallucinations," samples that could never occur in the training data. But where do such hallucinations come from? In this paper,…

Machine Learning · Computer Science 2024-08-27 Sumukh K Aithal , Pratyush Maini , Zachary C. Lipton , J. Zico Kolter

Large language models (LLMs) offer transformative potential for clinical decision support in spine surgery but pose significant risks through hallucinations, which are factually inconsistent or contextually misaligned outputs that may…

Machine Learning · Computer Science 2025-11-21 Dong Chen , Yanzhe Wei , Zonglin He , Guan-Ming Kuang , Canhua Ye , Meiru An , Huili Peng , Yong Hu , Huiren Tao , Kenneth MC Cheung

Model hallucination is one of the most critical challenges faced by Large Language Models (LLMs), especially in high-stakes code intelligence tasks. As LLMs become increasingly integrated into software engineering tasks, understanding and…

Software Engineering · Computer Science 2025-11-04 Cuiyun Gao , Guodong Fan , Chun Yong Chong , Shizhan Chen , Chao Liu , David Lo , Zibin Zheng , Qing Liao

Generative super-resolution (GSR) currently sets the state-of-the-art in terms of perceptual image quality, overcoming the "regression-to-the-mean" blur of prior non-generative models. However, from a human perspective, such models do not…

Computer Vision and Pattern Recognition · Computer Science 2026-01-12 Weiming Ren , Raghav Goyal , Zhiming Hu , Tristan Ty Aumentado-Armstrong , Iqbal Mohomed , Alex Levinshtein

Large Vision-Language Models (VLMs) have achieved remarkable success across diverse multimodal tasks but remain vulnerable to hallucinations rooted in inherent language bias. Despite recent progress, existing hallucination mitigation…

Computer Vision and Pattern Recognition · Computer Science 2026-02-12 Yilin Yang , Zhenghui Guo , Yuke Wang , Omprakash Gnawali , Sheng Di , Chengming Zhang

Whole slide imaging (WSI) is an emerging technology for digital pathology. The process of autofocusing is the main influence of the performance of WSI. Traditional autofocusing methods either are time-consuming due to repetitive mechanical…

Image and Video Processing · Electrical Eng. & Systems 2020-03-17 Qiang Li , Xianming Liu , Kaige Han , Cheng Guo , Xiangyang Ji , Xiaolin Wu

Computer methods in medical devices are frequently imperfect and are known to produce errors in clinical or diagnostic tasks. However, when deep learning and data-based approaches yield output that exhibit errors, the devices are frequently…

Image and Video Processing · Electrical Eng. & Systems 2025-08-21 Jason Granstedt , Prabhat Kc , Rucha Deshpande , Victor Garcia , Aldo Badano
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