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In this essay, we investigate some relations between Chemical Reaction Networks (CRN) and Mathematical Epidemiology (ME) and report on several pleasant surprises which we had simply by putting these two topics together. Firstly, we propose…

Molecular Networks · Quantitative Biology 2025-05-22 Florin Avram , Rim Adenane , Andrei D. Halanay , Matthew D. Johnston

Consensusability is an important property for many multi-agent systems (MASs) as it implies the existence of networked controllers driving the states of MAS subsystems to the same value. Consensusability is of interest even when the MAS…

Systems and Control · Electrical Eng. & Systems 2020-03-18 Mustafa Sahin Turan , Liang Xu , Giancarlo Ferrari Trecate

Complex, interconnected Cyber-physical Systems (CPS) are increasingly common in applications including smart grids and transportation. Ensuring safety of interconnected systems whose dynamics are coupled is challenging because the effects…

Systems and Control · Electrical Eng. & Systems 2023-01-02 Abdullah Al Maruf , Luyao Niu , Andrew Clark , J. Sukarno Mertoguno , Radha Poovendran

Step Chemical Reaction Networks (step CRNs) are an augmentation of the Chemical Reaction Network (CRN) model where additional species may be introduced to the system in a sequence of ``steps.'' We study step CRN systems using a weak subset…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-05-03 Rachel Anderson , Bin Fu , Aiden Massie , Gourab Mukhopadhyay , Adrian Salinas , Robert Schweller , Evan Tomai , Tim Wylie

The resilience of cyberphysical systems to denial-of-service (DoS) and integrity attacks is studied in this paper. The cyberphysical system is modeled as a linear structured system, and its resilience to an attack is interpreted in a graph…

Systems and Control · Electrical Eng. & Systems 2021-09-06 Bhaskar Ramasubramanian , M. A. Rajan , M. Girish Chandra , Rance Cleaveland , Steven I. Marcus

We examine reaction networks (CRNs) through their associated continuous-time Markov processes. Studying the dynamics of such networks is in general hard, both analytically and by simulation. In particular, stationary distributions of…

Probability · Mathematics 2022-03-28 Linard Hoessly

An algorithm is given in this paper for the computation of dynamically equivalent weakly reversible realizations with the maximal number of reactions, for chemical reaction networks (CRNs) with mass action kinetics.

Dynamical Systems · Mathematics 2015-03-19 Gabor Szederkenyi , Katalin M. Hangos , Zsolt Tuza

We study how the properties of allowing multiple positive nondegenerate equilibria (MPNE) and multiple positive linearly stable equilibria (MPSE) are inherited in chemical reaction networks (CRNs). Specifically, when is it that we can…

Dynamical Systems · Mathematics 2017-09-11 Murad Banaji , Casian Pantea

This paper proposes a reliable learning-based adaptive control framework for nonlinear multi-agent systems (MASs) subject to Denial-of-Service (DoS) attacks and singular control gains, two critical challenges in cyber-physical systems. A…

Systems and Control · Electrical Eng. & Systems 2025-12-11 Ladan Khoshnevisan , Xinzhi Liu

Color and structure are the two pillars that combine to give an image its meaning. Interested in critical structures for neural network recognition, we isolate the influence of colors by limiting the color space to just a few bits, and find…

Computer Vision and Pattern Recognition · Computer Science 2022-08-18 Yunzhong Hou , Liang Zheng , Stephen Gould

We explore the range of probabilistic behaviours that can be engineered with Chemical Reaction Networks (CRNs). We show that at steady state CRNs are able to "program" any distribution with finite support in $\mathbb{N}^m$, with $m \geq 1$.…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-04-25 Luca Cardelli , Marta Kwiatkowska , Luca Laurenti

The nonlinearities found in molecular networks usually prevent mathematical analysis of network behaviour, which has largely been studied by numerical simulation. This can lead to difficult problems of parameter determination. However,…

Molecular Networks · Quantitative Biology 2012-07-17 R. L. Karp , M. Pérez Millán , T. Dasgupta , A. Dickenstein , J. Gunawardena

Consensusability of multi-agent systems (MASs) certifies the existence of a distributed controller capable of driving the states of each subsystem to a consensus value. We study the consensusability of linear interconnected MASs (LIMASs)…

Systems and Control · Electrical Eng. & Systems 2021-05-12 Mustafa Sahin Turan , Liang Xu , Giancarlo Ferrari-Trecate

Chemical reaction networks taken with mass-action kinetics are dynamical systems that arise in chemical engineering and systems biology. In general, determining whether a chemical reaction network admits multiple steady states is difficult,…

Dynamical Systems · Mathematics 2012-02-15 Badal Joshi , Anne Shiu

Here we focus on the challenge of verifying the correctness of molecular implementations of abstract chemical reaction networks, where operation in a well-mixed "soup" of molecules is stochastic, asynchronous, concurrent, and often involves…

Computational Engineering, Finance, and Science · Computer Science 2019-10-01 Seung Woo Shin , Chris Thachuk , Erik Winfree

Upon a matrix representation of a binary bipartite network, via the permutation invariance, a coupling geometry is computed to approximate the minimum energy macrostate of a network's system. Such a macrostate is supposed to constitute the…

Applications · Statistics 2018-02-02 Jiahui Guan , Hsieh Fushing

We establish a Hessian geometric structure in chemical thermodynamics which describes chemical reaction networks (CRNs) with equilibrium states. In our setup, the ideal gas assumption and mass action kinetics are not required. The existence…

Statistical Mechanics · Physics 2022-08-30 Yuki Sughiyama , Dimitri Loutchko , Atsushi Kamimura , Tetsuya J. Kobayashi

In this contribution, we establish a model for multichannel cognitive radio networks (CRNs) using the theory of priority queues. This model enables us to conduct a performance analysis in the most general form by the derivation of the…

Networking and Internet Architecture · Computer Science 2014-01-28 Navid Tadayon , Sonia Aissa

The dynamics of a chemical reaction network (CRN) is often modelled under the assumption of mass action kinetics by a system of ordinary differential equations (ODEs) with polynomial right-hand sides that describe the time evolution of…

Dynamical Systems · Mathematics 2023-01-05 Radek Erban , Hye-Won Kang

Near-infrared (NIR; a.k.a.\ NIRS) deep-learning studies in chemometrics increasingly report mutually inconsistent conclusions regarding convolutional neural network (CNN) design, including small versus large kernels, shallow versus deep…

Machine Learning · Computer Science 2026-05-05 Dário Passos
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