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We introduce a mixed-integer linear programming (MILP) framework capable of determining whether a chemical reaction network possesses the property of being endotactic or strongly endotactic. The network property of being strongly endotactic…

Numerical Analysis · Mathematics 2014-12-16 Matthew D. Johnston , Casian Pantea , Pete Donnell

The well-known Deficiency One Theorem gives structural conditions on a chemical reaction network under which, for any set of parameter values, the steady states of the corresponding mass action system may be easily characterized. It is also…

Optimization and Control · Mathematics 2016-03-02 Matthew D. Johnston

In neural circuits, recurrent connectivity plays a crucial role in network function and stability. However, existing recurrent spiking neural networks (RSNNs) are often constructed by random connections without optimization. While RSNNs can…

Neural and Evolutionary Computing · Computer Science 2024-06-21 Wenrui Zhang , Hejia Geng , Peng Li

In this thesis a comprehensive verification framework is proposed to contend with some important issues in composability verification and a verification process is suggested to verify composability of different kinds of systems models, such…

Software Engineering · Computer Science 2023-01-10 Imran Mahmood

We analyze the computational complexity of basic reconfiguration problems for the recently introduced surface Chemical Reaction Networks (sCRNs), where ordered pairs of adjacent species nondeterministically transform into a different…

Due to its non-crystalline nature, the glassy state has remained one the most exciting scientific challenges. To study such materials, Molecular Dynamics (MD) simulations have been extensively used because they provide a direct view into…

Materials Science · Physics 2015-06-23 Mathieu Bauchy

Complex, interconnected cyber-physical systems (CPS) are increasingly prevalent in domains such as power systems. Cyber-resilient architectures have been proposed to recover compromised cyber components of CPS. Recent works have studied…

Systems and Control · Electrical Eng. & Systems 2026-03-17 Eman Badr , Abdullah Al Maruf

Models with transparent inner structure and high classification performance are required to reduce potential risk and provide trust for users in domains like health care, finance, security, etc. However, existing models are hard to…

Machine Learning · Computer Science 2020-02-21 Zhuo Wang , Wei Zhang , Ning Liu , Jianyong Wang

Autocatalysis is an important feature of metabolic networks, contributing crucially to the self-maintenance of organisms. Autocatalytic subsystems of chemical reaction networks (CRNs) are characterized in terms of algebraic conditions on…

Molecular Networks · Quantitative Biology 2026-05-06 Richard Golnik , Thomas Gatter , Peter F. Stadler , Nicola Vassena

Machine learning approaches to nuclear mass prediction have achieved remarkable accuracy, but typically rely on existing theoretical baselines or hand-crafted physics features. Here we demonstrate that these prerequisites can be supplanted…

Nuclear Theory · Physics 2026-03-11 Peiwen Zai , Wei Cheng , Feng-Shou Zhang

We identify the thermodynamic conditions necessary to observe indefinite growth in homogeneous open chemical reaction networks (CRNs) satisfying mass action kinetics. We also characterize the thermodynamic efficiency of growth by…

Molecular Networks · Quantitative Biology 2024-12-05 Shesha Gopal Marehalli Srinivas , Francesco Avanzini , Massimiliano Esposito

Across many disciplines, chemical reaction networks (CRNs) are an established population model defined as a system of coupled nonlinear ordinary differential equations. In many applications, for example, in systems biology and epidemiology,…

Systems and Control · Electrical Eng. & Systems 2023-01-23 Kim G. Larsen , Daniele Toller , Mirco Tribastone , Max Tschaikowski , Andrea Vandin

Inferring chemical reaction networks (CRN) from concentration time series is a challenge encouragedby the growing availability of quantitative temporal data at the cellular level. This motivates thedesign of algorithms to infer the…

Quantitative Methods · Quantitative Biology 2023-02-09 Julien Martinelli , Jeremy Grignard , Sylvain Soliman , Annabelle Ballesta , François Fages

The small gain condition is sufficient for input-to-state stability (ISS) of interconnected systems. However, verification of the small gain condition requires large amount of computations in the case of a large size of the system. To…

Dynamical Systems · Mathematics 2012-06-29 S. Dashkovskiy , M. Kosmykov

The evolution of quantization and mixed-precision techniques has unlocked new possibilities for enhancing the speed and energy efficiency of NNs. Several recent studies indicate that adapting precision levels across different parameters can…

Machine Learning · Computer Science 2025-09-19 Giorgos Armeniakos , Alexis Maras , Sotirios Xydis , Dimitrios Soudris

Multi-Agent Systems (MAS) are adopted and tested with many complex and critical industrial applications, which are required to be adaptive, scalable, context-aware, and include real-time constraints. Industrial Control Networks (ICN) are…

Systems and Control · Computer Science 2015-06-18 Hosny A. Abbas , Samir I. Shaheen , Mohammed H. Amin

The networked combat system-of-system (CSOS) is the trend of combat development with the innovation of technology. The achievement of combat effectiveness requires CSOS to have a good ability to deal with external interference. Here we…

Systems and Control · Electrical Eng. & Systems 2022-12-12 Jintao Yu , Bing Xiao , Yuzhu Cui

The reservoir computing networks (RCNs) have been successfully employed as a tool in learning and complex decision-making tasks. Despite their efficiency and low training cost, practical applications of RCNs rely heavily on empirical…

Machine Learning · Computer Science 2021-12-14 Wei Miao , Vignesh Narayanan , Jr-Shin Li

Two networks are said to be linearly conjugate if the solution of their dynamic equations can be transformed into each other by a positive linear transformation. The study on dynamical equivalence in chemical kinetic systems was initiated…

Algebraic Geometry · Mathematics 2021-10-27 Allen L. Nazareno , Raymond Paul L. Eclarin , Eduardo R. Mendoza , Angelyn R. Lao

Recently, a novel two-phase framework named mol-infer for inference of chemical compounds with prescribed abstract structures and desired property values has been proposed. The framework mol-infer is primarily based on using mixed integer…

Machine Learning · Computer Science 2025-07-08 Jianshen Zhu , Naveed Ahmed Azam , Kazuya Haraguchi , Liang Zhao , Tatsuya Akutsu