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This is a method for discrete event simulation specified by survival analysis. It presents a sequence of steps. First, hazard rates from survival analysis specify the rates of a set of counting processes. Second, those counting processes…

Computation · Statistics 2016-10-14 Andrew J. Dolgert

Survival analysis is crucial for many medical applications, but remains challenging for modern machine learning due to limited data, censoring, and the heterogeneity of tabular covariates. While the prior-fitted paradigm, which relies on…

Machine Learning · Computer Science 2026-05-14 Dmitrii Seletkov , Paul Hager , Georgios Kaissis , Rickmer Braren , Daniel Rueckert , Raphael Rehms

We define a new class of predicates called equilevel predicates on a distributive lattice which eases the analysis of parallel algorithms. Many combinatorial problems such as the vertex cover problem, the bipartite matching problem, and the…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-11-13 Vijay K. Garg , Robert P. Streit

Propensity scores are commonly used to reduce the confounding bias in non-randomized observational studies for estimating the average treatment effect. An important assumption underlying this approach is that all confounders that are…

Methodology · Statistics 2022-08-02 Youfei Yu , Jiacong Du , Min Zhang , Zhenke Wu , Andrew M. Ryan , Bhramar Mukherjee

Document-level Event Argument Extraction (EAE) requires the model to extract arguments of multiple events from a single document. Considering the underlying dependencies between these events, recent efforts leverage the idea of "memory",…

Computation and Language · Computer Science 2023-10-26 Quzhe Huang , Yanxi Zhang , Dongyan Zhao

Deep generative models such as conditional variational autoencoders (CVAEs) have shown great promise for predicting trajectories of surrounding agents in autonomous vehicle planning. State-of-the-art models have achieved remarkable accuracy…

Robotics · Computer Science 2025-10-14 Yongxi Cao , Julian F. Schumann , Jens Kober , Joni Pajarinen , Arkady Zgonnikov

We propose TRACIE, a novel temporal reasoning dataset that evaluates the degree to which systems understand implicit events -- events that are not mentioned explicitly in natural language text but can be inferred from it. This introduces a…

Computation and Language · Computer Science 2021-05-11 Ben Zhou , Kyle Richardson , Qiang Ning , Tushar Khot , Ashish Sabharwal , Dan Roth

The level of tumour-infiltrating lymphocytes (TILs) is a prognostic factor for patients with (triple-negative) breast cancer (BC). Computational TIL assessment (CTA) has the potential to assist pathologists in this labour-intensive task,…

We present ProbMetab, an R package which promotes substantial improvement in automatic probabilistic LC-MS based metabolome annotation. The inference engine core is based on a Bayesian model implemented to: (i) allow diverse source of…

In medicine, survival analysis studies the time duration to events of interest such as mortality. One major challenge is how to deal with multiple competing events (e.g., multiple disease diagnoses). In this work, we propose a…

Machine Learning · Computer Science 2022-06-29 Zifeng Wang , Jimeng Sun

Estimating causal effects on time-to-event outcomes from observational data is particularly challenging due to censoring, limited sample sizes, and non-random treatment assignment. The need for answering such "when-if" questions--how the…

Machine Learning · Computer Science 2025-11-19 Jessy Xinyi Han , Devavrat Shah

Modern manufacturing environments demand not only accurate predictions but also interpretable insights to process anomalies, root causes, and potential interventions. Existing AI systems often function as isolated black boxes, lacking the…

Artificial Intelligence · Computer Science 2025-10-15 Chathurangi Shyalika , Aryaman Sharma , Fadi El Kalach , Utkarshani Jaimini , Cory Henson , Ramy Harik , Amit Sheth

This study introduces a novel methodology for modelling patient emotions from online patient experience narratives. We employed metadata network topic modelling to analyse patient-reported experiences from Care Opinion, revealing key…

Computation and Language · Computer Science 2024-01-10 Curtis Murray , Lewis Mitchell , Jonathan Tuke , Mark Mackay

Tabular biomedical data poses challenges in machine learning because it is often high-dimensional and typically low-sample-size (HDLSS). Previous research has attempted to address these challenges via local feature selection, but existing…

Machine Learning · Computer Science 2024-06-04 Xiangjian Jiang , Andrei Margeloiu , Nikola Simidjievski , Mateja Jamnik

Precision medicine is an evolving area in the medical field and rely on biomarkers to make patient enrichment decisions, thereby providing drug development direction. A traditional statistical approach is to find the cut-off that leads to…

Methodology · Statistics 2025-04-14 Gina D'Angelo , Xiaowen Tian , Chuyu Deng , Xian Zhou

Surrogate endpoint (SE) for overall survival in cancer patients is essential to improving the efficiency of oncology drug development. In practice, we may discover a new patient level association with survival, based on one or more clinical…

Applications · Statistics 2022-11-08 Wei Zou

Heterogeneous treatment effects (HTEs) are commonly identified during randomized controlled trials (RCTs). Identifying subgroups of patients with similar treatment effects is of high interest in clinical research to advance precision…

Machine Learning · Computer Science 2022-12-06 Peniel N. Argaw , Elizabeth Healey , Isaac S. Kohane

The rapid advancements in artificial intelligence (AI) have revolutionized smart healthcare, driving innovations in wearable technologies, continuous monitoring devices, and intelligent diagnostic systems. However, security, explainability,…

Machine Learning · Computer Science 2024-10-02 Prasenjit Maji , Amit Kumar Mondal , Hemanta Kumar Mondal , Saraju P. Mohanty

With the increased availability of large databases of electronic health records (EHRs) comes the chance of enhancing health risks screening. Most post-marketing detections of adverse drug reaction (ADR) rely on physicians' spontaneous…

Applications · Statistics 2018-01-29 Maryan Morel , Emmanuel Bacry , Stéphane Gaïffas , Agathe Guilloux , Fanny Leroy

Medical Cyber-physical Systems (MCPS) are vulnerable to accidental or malicious faults that can target their controllers and cause safety hazards and harm to patients. This paper proposes a combined model and data-driven approach for…

Artificial Intelligence · Computer Science 2021-04-14 Xugui Zhou , Bulbul Ahmed , James H. Aylor , Philip Asare , Homa Alemzadeh
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