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Survival analysis plays a vital role in making clinical decisions. However, the models currently in use are often difficult to interpret, which reduces their usefulness in clinical settings. Prototype learning presents a potential solution,…
Drug combinations can cause adverse drug-drug interactions(DDIs). Identifying specific effects is crucial for developing safer therapies. Previous works on DDI event prediction have typically been limited to using labels of specific events…
Preventable medical errors are estimated to be among the leading causes of injury and death in the United States. To prevent such errors, healthcare systems have implemented patient safety and incident reporting systems. These systems…
Radiology reports contain a diverse and rich set of clinical abnormalities documented by radiologists during their interpretation of the images. Comprehensive semantic representations of radiological findings would enable a wide range of…
We introduce a Bayesian nonparametric inference approach for aggregate adverse event (AE) monitoring across studies. The proposed model seamlessly integrates external data from historical trials to define a relevant background rate and…
Clinical trials are the basis of Evidence-Based Medicine. Trial results are reviewed by experts and consensus panels for producing meta-analyses and clinical practice guidelines. However, reviewing these results is a long and tedious task,…
We present TRACE (Transformer-based Risk Assessment for Clinical Evaluation), a novel method for clinical risk assessment based on clinical data, leveraging the self-attention mechanism for enhanced feature interaction and result…
Predicting critical health outcomes such as patient mortality and hospital readmission is essential for improving survivability. However, healthcare datasets have many concurrences that create complexities, leading to poor predictions.…
Identifying events and mapping them to pre-defined event types has long been an important natural language processing problem. Most previous work has been heavily relying on labor-intensive and domain-specific annotations while ignoring the…
Tracking tumor lesions across serial CT scans is essential for oncological response assessment. Existing automated methods face a fundamental trade-off: end-to-end trackers achieve high automation but offer no opportunity to correct silent…
Objectives: Pancreatic cancer is a lethal disease, hard to diagnose and usually results in poor prognosis and high mortality. Developing an artificial intelligence (AI) algorithm to accurately and universally predict the early cancer risk…
External control arms can inform early clinical development of experimental drugs and provide efficacy evidence for regulatory approval. However, accessing sufficient real-world or historical clinical trials data is challenging. Indeed,…
Post-traumatic stress disorder (PTSD) is a mental disorder that can be developed after witnessing or experiencing extremely traumatic events. PTSD can affect anyone, regardless of ethnicity, or culture. An estimated one in every eleven…
In the realm of cancer treatment, summarizing adverse drug events (ADEs) reported by patients using prescribed drugs is crucial for enhancing pharmacovigilance practices and improving drug-related decision-making. While the volume and…
Knowing the state of our health at every moment in time is critical for advances in health science. Using data obtained outside an episodic clinical setting is the first step towards building a continuous health estimation system. In this…
Diagnostic investigation has an important role in risk stratification and clinical decision making of patients with suspected and documented Coronary Artery Disease (CAD). However, the majority of existing tools are primarily focused on the…
Multicriteria decision analysis (MCDA) is a widely used tool to support decisions in which a set of alternatives should be ranked or classified based on multiple criteria. Recent studies in MCDA have shown the relevance of considering not…
Temporal complex event forecasting aims to predict the future events given the observed events from history. Most formulations of temporal complex event are unstructured or without extensive temporal information, resulting in inferior…
In medical image segmentation tasks, the domain gap caused by the difference in data collection between training and testing data seriously hinders the deployment of pre-trained models in clinical practice. Continual Test-Time Adaptation…
Background: Artificial Intelligence (AI) clinical decision support (CDS) systems have the potential to augment surgical risk assessments, but successful adoption depends on an understanding of end-user needs and current workflows. This…